Krystle J McLaughlin

Stick chemistry: High-throughput method for finding new molecular glues. A visualization of a new molecular-glue degrader bound to cereblon and a protein target of interest.

Molecular glues are enjoying the spotlight, but discovering new ones is often a matter of luck. A new method, developed by @scripps.edu chemist @michael-erb.bsky.social and colleagues, aims to discover new glues more intentionally with a “target-based” approach. cen.acs.org/biological-c...
#chemsky🧪

This one hits hard.

Always bombing somewhere 🫩

Help power the Summer Fight For Science movement! Donate now to help mobilize the fight for science and democracy. Every contribution matters!

I just donated! Your contribution is needed ASAP to fuel this existential fight and save science in America. Donate now for today, tomorrow, and the years to come.
Rally to Take Back Our Science is on Saturday March 7th, 2026 in Washington DC.
act.standupforscience.net/fundraising/... 🧪

Make it viral.

Like those before it, that insane, vile DHS statement about the Minneapolis shooting isn't about covering anything up. It's performative lying.

They aren't trying to persuade anyone that their agents did nothing wrong. They're trying to project that their agents can get away with anything.

‘She was an amazing human being:’ Mother identifies woman shot, killed by ICE agent Renee Nicole Good, 37, lived in the Twin Cities with her partner.

"Renee was one of the kindest people I’ve ever known,” her mother said. “She was extremely compassionate. She’s taken care of people all her life. She was loving, forgiving and affectionate. She was an amazing human being.” www.startribune.com/she-was-an-a...

Members of Congress: stop posting online and APPEAR, PHYSICALLY on the steps of the Capitol to decry this unconstitutional violation of domestic & international law. SHOW THE PEOPLE the level of danger we are facing as a country.
@housedemocrats.bsky.social
@senatedemocrats.bsky.social

He legit just pardoned the president of Honduras for drug trafficking but now Maduro is going to stand trial for “narco terrorism.” This all makes a lot of sense and definitely isn’t about oil.

Trump promised no “new stupid wars,” yet he’s starting one with Venezuela without congressional approval.

People can’t afford groceries and millions are losing healthcare, but this is where his focus is.

This is unconstitutional and not what the American people asked for.

Seven feel-good science stories to restore your faith in 2025 Immense progress in gene-editing, drug discovery and conservation are just some of the reasons to be cheerful about 2025.

☺️ 🧪
www.nature.com/articles/d41...

🙌🏽

Grey shipping box seatbelted into the front seat of a car with driver smiling.

Another day, another dewar.

Appeal to the crystal gods for me today, friends 🫠 🤞🏽

#research #crystallography #biochemistry 🧪

😎😎😎😎 GOOD THINGS CAN STILL HAPPEN 😎😎😎😎

Thoughts on ITC preference- the good/bad/annoying- between a Microcal PEAQ-ITC and TA Affinity ITC??

🧪 #Chemsky #Sciencesky

Thoughts on ITC preference- the good/bad/annoying- between a Microcal PEAQ-ITC and TA Affinity ITC??

🧪 #Chemsky #Sciencesky

It is really funny that Jimmy Kimmel Live showed more moral fortitude and adherence to a system of values than Columbia University

"Who would have predicted this?"

- Black women did.
- Trans people did.
- The *entire* disability community did.
- The anarchists did.
- Post-Evangelicals did.

"Well why didn't I hear them."

You did. But you disregarded us as "extremists" and "alarmists". And you are still calling us that.

Come be my colleague! We are hiring a full-time Lecturer in Organic Chemistry. If you are interested in teaching/curricular development & pedagogy this is a great position for you!
Review of applications begins 10/6/25

Happy to answer any questions!
Full details here: tinyurl.com/vcorganiclec...
🧪

Come be my colleague! We are hiring a full-time Lecturer in Organic Chemistry. If you are interested in teaching/curricular development & pedagogy this is a great position for you!
Review of applications begins 10/6/25

Happy to answer any questions!
Full details here: tinyurl.com/vcorganiclec...
🧪

We were pleased to publish some of the results from this course, some in our recent 'Empowering education through structural genomics' focused issue: journals.iucr.org/special_issu...

🧪

Two scientists looking at a computer screen

Excited to share this story on the protein crystallography CURE I developed and have been teaching for the last 3 years!

www.vassar.edu/news/student...

This course is supported by my #CottrellScholars Award from RCSA.

@rescorp.org
@vassar.bsky.social

#grantsinaction #biochemistry

Public media has been defunded. Your support keeps journalists on the ground, lifts unheard voices, and connects communities.

Help us plan for what’s next. Make a monthly gift today. Stand with public media: n.pr/458sOhq

Also if you at at #ACA2025 and missed my talk today, you can catch my other talk on Tuesday in 4.2.3 Engaging Students with Crystallography where I will share lessons learned from creating/running a protein crystallography CURE!

Gave a talk in the Hot Structures session today at #ACA2025 in Chicago!

Fun fact: the first conference talk I ever gave was in 2010 at my first ACA meeting, also in the Hot Structures session, also in Chicago!! (See bonus pic below of me attending ACA2010) ☺️

And if you see me at #ACA2025 say hi!

And now @biophyskrys.bsky.social giving a hot strucutres talk on BoPDA, a polysaccharide deacetylase. Another great study and talk! #ACA2025 @acastructuralsci.bsky.social

Scientist presenting talk

Scientist presenting talk

Scientist presenting talk

Scientist presenting talk

Great Hot Structures session at #ACA2025!
ACA Etter Student Award winner Sarah Narehood, @biophyskrys.bsky.social, Nikolas Capra, Rachel Kretsch, Debanu Das, Daniel Richman
@acastructuralsci.bsky.social

ACA 2025 Starter Pack for attendees of the 75th Annual Meeting.
Tried to include everyone, feel free to tag yourself or others missed. Connecting the community at #ACA2025!
@acastructuralsci.bsky.social @rcsbpdb.bsky.social
🔗 go.bsky.app/JAmraSp