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Carla Abreu

@carlamcabreu.bsky.social

Team leader @i3S_UPorto, passionate about animal development and congenital disease mechanisms, with a particular focus on germline and neuro development. Enthusiast of ciliary molecular motors and cilia-mediated signaling.

43 Followers  |  76 Following  |  1 Posts  |  Joined: 28.03.2025  |  1.5949

Latest posts by carlamcabreu.bsky.social on Bluesky

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Removal of the Ciliary Gate Allows Axoneme Extension in the Absence of Retrograde IFT The transition zone (TZ) is a selective barrier that maintains ciliary compartmentalization by controlling protein entry and exit. Cilia assembly requires the crossing of this barrier by intraflagella...

Can #cilia grow without #dynein-2 mediated retrograde #IFT?👀

Yes, they can! Removing the ciliary gate lets trapped IFT components escape via diffusion & ciliary #EVs, driving axoneme elongation.
👉 doi.org/10.1101/2025...

🧬 Work led with @dantas-lab.bsky.social, in collaboration with Peterman lab.

28.10.2025 11:39 — 👍 4    🔁 1    💬 0    📌 0

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