Katharina Hoff's Avatar

Katharina Hoff

@katharinahoff.bsky.social

Genome annotation geek at University of Greifswald, always interested in friendly scientific collaboration. Developer of BRAKER, GALBA, MakeHub and other Gaius-Augustus tools.

740 Followers  |  1,553 Following  |  270 Posts  |  Joined: 13.09.2023
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Posts by Katharina Hoff (@katharinahoff.bsky.social)

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Involuntarily learnt a lot about xylitol induced insulin secretion jn dogs during the weekend. Luckily the little patient is recovering well. (We will never know what she ateโ€ฆ but a chewing gum seems realistic.)

02.03.2026 07:09 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Research Assistant - Bioinformatics 26/Sa05 Stellenausschreibung Bioinformatik

PhD position open! Bioinformatics | Python | Phytoplankton genomics | Deep learning. Funded until 2029. If you love code AND biology, we want to hear from you. Deadline: March 15! www.uni-greifswald.de/en/universit...

24.02.2026 10:01 โ€” ๐Ÿ‘ 8    ๐Ÿ” 9    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

So how many of my colleagues are PAYING OpenAI to use their LLM again???? You see where your money is going?

28.02.2026 13:38 โ€” ๐Ÿ‘ 4    ๐Ÿ” 4    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Und dann bewirbt frau sich mal in Norwegen oder NL - holla, das geht zackig! Es kรถnnte durchaus anders laufen ๐Ÿ™„

27.02.2026 12:37 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Hey #Physco sphere! What's your favorite protocol for purifying total RNA (or mRNA) from moss gametophores?

27.02.2026 12:28 โ€” ๐Ÿ‘ 10    ๐Ÿ” 3    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 0
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Marnix Medema appointed chair of Bioinformatics at WUR Marnix Medema has been appointed Chair of the Bioinformatics Group at Wageningen University & Research as of 1 February. He aims to further strengthen bioinformatics as a connecting discipline within ...

Our chairgroup Bioinformatics at Wageningen University changed leadership: prof. Dick de Ridder (@dickderidder.bsky.social) moved on to become Dean of Education and is now followed up by prof. Marnix Medema. Congrats @marnixmedema.bsky.social! www.wur.nl/en/news/marn...

12.02.2026 10:41 โ€” ๐Ÿ‘ 5    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
Research Assistant - Bioinformatics 26/Sa05 Stellenausschreibung Bioinformatik

PhD position open! Bioinformatics | Python | Phytoplankton genomics | Deep learning. Funded until 2029. If you love code AND biology, we want to hear from you. Deadline: March 15! www.uni-greifswald.de/en/universit...

24.02.2026 10:01 โ€” ๐Ÿ‘ 8    ๐Ÿ” 9    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Daylight during our morning walk ๐Ÿ˜

24.02.2026 05:57 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Divergent representation and processing of task cues in sensory and prefrontal cortices of preterm-born mice - Nature Communications Here authors show that the function of prefrontal cortex, an area that controls executive function and cognition, is impaired on a cellular and network level in mice born preterm.

New paper alert! The latest from my lab describing atypicalities in the processing of cues in the PFC and V1 of preterm mice trained on a visual discrimination task: www.nature.com/articles/s41...

05.02.2026 22:14 โ€” ๐Ÿ‘ 2    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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#IchbinHanna-Grรผnderin schmeiรŸt hin: Amrei Bahr wurde Juniorprofessorin โ€“ und verlรคsst die Wissenschaft Mit ihrem Einsatz fรผr bessere Arbeitsbedingungen an Unis wurde Amrei Bahr bekannt und lรถste eine Bewegung aus, die das Wissenschaftssystem รคndern will. Jetzt gab die Juniorprofessorin ihren Ausstieg a...

Gestern hab ich bekannt gegeben, dass ich spรคtestens 2028 aus der Wissenschaft aussteigen werd โ€” darรผber schreibt @evamurasov.bsky.social nun im @tagesspiegel.de. Zig Kommentare & Nachrichten zeigen mir: Sehr viele Wissenschaftler_innen hadern. Bedingungen mรผssen dringend besser werden! #IchBinHanna

20.02.2026 18:28 โ€” ๐Ÿ‘ 593    ๐Ÿ” 153    ๐Ÿ’ฌ 33    ๐Ÿ“Œ 8

do nextflow pipeline developers consider temporary storage needs when developing pipelines?

I love nextflow, but I feel like the modular structure encourages design choices that cause temporary storage to explode.

19.02.2026 15:09 โ€” ๐Ÿ‘ 5    ๐Ÿ” 1    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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Scientists have seen Asgard archaea crawling for the first time. When it comes to the origin of eukaryotes, this is like seeing a feathered dinosaur in the wild. (Video courtesy of Philipp Ralder)

18.02.2026 20:09 โ€” ๐Ÿ‘ 470    ๐Ÿ” 137    ๐Ÿ’ฌ 10    ๐Ÿ“Œ 19
Annotation of 200 Insect Genomes with BRAKER for Consistent Comparisons across Species - Scientific Data Scientific Data - Annotation of 200 Insect Genomes with BRAKER for Consistent Comparisons across Species

Congratulations to @stepbystepsolution.bsky.social to the manuscript on genome annotation of 200 insect genomes, a result his work within of @gevol.bsky.social ! doi.org/10.1038/s415...

19.02.2026 12:10 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Genome Annotation Workshop 2026 Providing scientists with a comprehensive overview of eukaryotic genome annotation approaches.

๐Ÿ’ป๐Ÿงฌ Keen to learn about eukaryotic genome annotation?

Registration is now open for our 2026 online #genomeannotation course, led by our core #bioinformatics team.

โžก๏ธ buff.ly/sonWCgT

22.10.2025 10:01 โ€” ๐Ÿ‘ 6    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Unmasked model for all genomes unless you are sure you masked exactly like the training data was masked (which varies).

16.02.2026 16:13 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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The new diatom Tiberius parameters for unmasked genomes illustrate the gain in accuracy that we often observe compared to parameters for unmasked genomes. #geneprediction #genomeannotation #diatoms #bacillariophyta github.com/Gaius-August...

16.02.2026 08:59 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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GitHub - Gaius-Augustus/Tiberius: Tiberius is a deep learning gene finder. Tiberius is a deep learning gene finder. Contribute to Gaius-Augustus/Tiberius development by creating an account on GitHub.

We have a new insect parameter set for unmasked genomes and a new fungal parameter set for unmasked genomes. Both deliver accuracy superior to previous models for insects and fungi. #genomeannotation #geneprediction github.com/Gaius-August...

16.02.2026 08:49 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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GitHub - Gaius-Augustus/Tiberius: Tiberius is a deep learning gene finder. Tiberius is a deep learning gene finder. Contribute to Gaius-Augustus/Tiberius development by creating an account on GitHub.

What we more recently learnt about Tiberius: the models trained on softmasked genomes are very sensitive to how the genome was masked for inference. It seems safer to use models trained on unmasked genomes. #genomeannotation #geneprediction github.com/Gaius-August...

16.02.2026 08:48 โ€” ๐Ÿ‘ 11    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

I am very, very happy! I got a pull up bar for x-mas, and today, my dear husband installed it. Itโ€™s so much easier to grip than those cheap gymnastics rings that I have used until now. Can I do a pull up? No. But the pathetic-looking attempts have changed my life. Pain is gone since I started trying

15.02.2026 14:23 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

This article is now published! academic.oup.com/nargab/artic...
Weโ€™ve added a few new analyses. First off, we show that, while gene presence absence variation (PAV) scales with evolutionary distance in both plants and animals, the base level and rate of accrual are both twice as high in plants.

30.01.2026 12:41 โ€” ๐Ÿ‘ 23    ๐Ÿ” 17    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

#ProtistsOnSky
no 'swimming' by ๐˜๐˜ข๐˜ฎ๐˜ฑ๐˜บ๐˜ณ๐˜ฆ๐˜ญ๐˜ญ๐˜ข, definitively no 'staying still'. just a relaxed walk towards the lunch...

02.02.2026 00:00 โ€” ๐Ÿ‘ 200    ๐Ÿ” 74    ๐Ÿ’ฌ 5    ๐Ÿ“Œ 5

None of the test species was used for training Tiberius, but only Coemansia reversa was not used to train ANNEVO & Helixer.

01.02.2026 10:38 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Tiberius parameters for fungi incertae sedis will soon be available on Github.

01.02.2026 10:34 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Michelle and a friend sitting under the moonlight on the side of Mount Shasta. They started their climb that morning at 3 am! Photo courtesy of Michelle Stantial.

Michelle and a friend sitting under the moonlight on the side of Mount Shasta. They started their climb that morning at 3 am! Photo courtesy of Michelle Stantial.

"Once you get to the top, you get to ski all the way back down the mountain!" Read @lsubiosci.bsky.social PhD student @jacobcarignan.bsky.social's interview with Quantitative Ecologist Michelle Stantial about her ski mountaineering hobby:
thelattinlab.com/beyond-the-b...

15.09.2025 14:12 โ€” ๐Ÿ‘ 4    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Cyclosa Menge, 1866 (Araneidae) Orbโ€Weavers Build Stabilimenta That Resemble Larger Spiders The orb-weaving spider Cyclosa longicauda from Peru constructs unique stabilimenta from detritus and silk that visually resemble a larger spider. This previously undescribed behavior likely functions....

These orb-weaver spiders build FAKE SPIDER DECOYS in their webs, potentially to deter predators ๐Ÿคฏ onlinelibrary.wiley.com/doi/10.1002/...

12.11.2025 15:28 โ€” ๐Ÿ‘ 6    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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We ended the day on Wednesday with a computer lab session on gene expression analyses with Rachel Steward ๐Ÿ’ป๐Ÿ“Š #evomics2026

24.01.2026 10:09 โ€” ๐Ÿ‘ 18    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Morning lecture by Maliheh Mehrshad (@mehrshmali.bsky.social) on metagenomics and metatranscriptomics! ๐Ÿงช๐Ÿงฌ๐Ÿฆ  #evomics2026

24.01.2026 10:12 โ€” ๐Ÿ‘ 11    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Rosa Fernรกndez (@rosafernandez.bsky.social) introducing the field of Phylogenomics to our participants ๐Ÿ™Œ๐Ÿฝ๐Ÿงฌ๐ŸŒณ๐Ÿ’ป #evomics2026

24.01.2026 10:15 โ€” ๐Ÿ‘ 22    ๐Ÿ” 5    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Last computer lab session of the workshop we are back in the Genomics Adventure, with Guy Leonard (@guyleonard.bsky.social)!! ๐Ÿ™Œ๐Ÿฝ๐Ÿ’ป๐Ÿ™†๐Ÿปโ€โ™€๏ธ #evomics2026

24.01.2026 10:17 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0