Journal of Thrombosis and Haemostasis

@jthjournal.bsky.social commentary in the most recent issue about more VTE prevention is needed in pregnancy - www.jthjournal.org/article/S153...

It will be interesting to see what the new UK 37a green top guidelines advise in the Autumn

💡Turn your exciting research into high-impact publications!
Whether you presented at #ISTH2025 &/or have some other new & exciting science to share, watch this interview w/our editors & learn more about submitting to @ISTH.org @jthjournal.bsky.social or @rpth.bsky.social
bit.ly/46TLcfk

📢📢NEW research from @jthjournal.bsky.social!

Two new papers were released on stroke risk and prediction in #atrialfibrillation. Whether you’re a clinician or researcher, you won’t want to miss these insights. Visit jthjournal.org to explore this new research. #stroke #afib #af

Our webinar with Dr. Jean M. Connors has been rescheduled to August 1st!

Don’t miss this opportunity to hear from a top expert in the field!

#ISTH2025 #Hematology #MedicalEducation #ClinicalHematology @ash.hematology.org @isth.org @jthjournal.bsky.social @athnnews.bsky.social

Publications Spotlight: JTH & RPTH ISTH Publications – Research and Practice in Thrombosis and Haemostasis (RPTH) Research and Practice in Thrombosis and Haemostasis (RPTH) is the open-access, online-only journal of the ISTH. Foll...

📚Spotlight on ISTH publications at #ISTH2025:
✅ @rpth.bsky.social: As ISTH’s open-access, online-only journal, RPTH is drives innovation & accessibility in science.
✅ @jthjournal.bsky.social: JTH publishes peer-reviewed groundbreaking research, reviews & clinical guidance

Learn more: bit.ly/4k5PbID

New targets for antithrombotic medications: seeking to decouple thrombosis from hemostasis - PubMed Arterial and venous thromboses are the leading causes of morbidity and mortality worldwide. Numerous antithrombotic agents are currently available with antiplatelet, thrombolytic/fibrinolytic, and ant...

If you want to learn more about Factor XI inhibitors, check out this recent review article in @jthjournal.bsky.social
pubmed.ncbi.nlm.nih.gov/39675564/

Global EHR-based study shows ~6% of children with CHD develop VTE within a year post-surgery, with a 25% recurrence rate. Most cases involved LE-DVT. Highlights need for targeted thromboprophylaxis strategies in this high-risk population. #PedsCardio #Thrombosis www.jthjournal.org/article/S153...

Amazing and thorough discussion on the ISTH Hemophilia Guidelines contents & methodology live at #ISTH2025

See this paper in JTHfor more deconstruction of the guidelines #hemophilia #hemesky

www.jthjournal.org/article/S153...

Meta-analysis on GLP-1RA (vs. placebo) and VTE:
🔹 PE rates significantly lower 📉
🔹 VTE rates lower but not statistically significant
🔹 No difference in DVT
🔹 Study design matters: RCTs vs. observational data
Accepted for publication in JTH!
#ISTH2025 #VTE #GLP1RA #Thrombosis
@jthjournal.bsky.social

The @rpth.bsky.social and @jthjournal.bsky.social Editors presented the Editors awards this afternoon, including this one to Daniel Steiner.

Corticosteroids remain the go-to for managing transaminitis post-valoctocogene roxaparvovec in hemophilia A. Early, reactive treatment may help preserve FVIII levels. #GeneTherapy #HemophiliaA #HemeSky www.jthjournal.org/article/S153...

Interesting discussion on high open access fees, increase of high quality papers from China & usage of Generative AI. More tools are needed #isth2025 @isth.org @jthjournal.bsky.social @rpth.bsky.social

And we're off #isth2025
EIC Ton Lisman @jthjournal.bsky.social introduces key points! Follow them on @linkedin.com

Considerations for use of generative AI in publication presented at the Publication Session #ISTH2025 @jthjournal.bsky.social

Find the @rpth.bsky.social and @jthjournal.bsky.social editors in PUB01 - The evolving landscape of academic publishing!

📍Room 151 A&B
⏰ 10:30-11:30

🗣️ @profmakris.bsky.social, Ton Lisman and Suzanne Cannegieter with host Donna DiMichele

🩺 In the PAUSE-2 pilot trial, perioperative management of DOACs in patients undergoing high-bleed-risk surgery or neuraxial procedures was found feasible. Both ASRA- and PAUSE-based strategies achieved similar pre-op DOAC levels, supporting a larger trial.

www.jthjournal.org/article/S153...

Just in time for the #ISTH2025 congress!
@ISTH.org releases its Updated Clinical Practice Guidelines on the Diagnosis and Treatment of TTP.
Learn more ⬇️and if you are attending #ISTH2025, don't miss the Guidelines Session GG01 on Saturday at 09:30 (US ET)
bit.ly/3G8zaUp

Blocking tubulin detyrosination via VASH1-SVBP inhibition enhances proplatelet formation & boosts platelet counts—no impact on function. A novel understanding of the megakaryocyte tubulin code beyond tubulin isotypes. #Platelet #HemeSky www.jthjournal.org/article/S153...

What are the barriers to recruitment and participation in RCTs evaluating postpartum thromboprophylaxis? This qualitative study reveals trust in providers, altruism, and risk perception as key motivators and barriers. Important insights for future trial design.
www.jthjournal.org/article/S153...

Follow our #isth2025 updates and/or these great thrombosis & haemostasis people #hemesky
@isth.org @jthjournal.bsky.social @rpth.bsky.social

How should women with AT deficiency be managed during pregnancy? This multicenter study shows that high-dose LMWH and peripartum AT concentrate may reduce venous thrombosis risk.

www.jthjournal.org/article/S153...

New study uncovers a zebrafish-specific interaction between TPO receptor (zTpoR) and Mapk14a (p38 MAPKα), crucial for thrombocyte development. This direct interaction, absent in humans, regulates thrombocyte count and clotting via unique signaling. #zebrafish
www.jthjournal.org/article/S153...

More #isth2025 #hemesky here

Explore the #June2025 issue of JTH! Highlights: cancer-linked SVT, GPVI malfunction in young platelets, DOAC failure in VTE, and device-induced thrombosis insights. 🩸 jthjournal.org #VTE #hematology

www.jthjournal.org/current

New data reveal a prothrombotic shift in cirrhosis: despite reduced plasmin generation, thrombin generation remains intact—creating a disbalance between coagulation and fibrinolysis. TG/PG ratio may be a novel marker of thrombotic risk. #cirrhosis #thrombosis
www.jthjournal.org/article/S153...

And a bonus one too 🤗

🩸 In NSCLC patients starting chemo, elevated FXIa:AT and TAT levels predict VTE and mortality. A new biomarker-based score stratifies risk, offering a potential tool for early intervention. #NSCLC #VTE #oncology #thrombosis #HemeSky
www.jthjournal.org/article/S153...

🧪 New findings challenge assumptions about young platelets: during stress thrombopoiesis, newly formed platelets show a transient defect in GPVI signaling. Full function appears to develop only after circulation time. #platelets #GPVI #hematology

🧪 Real-world study validates a new ADAMTS-13 assay: fast, reliable, and accurate for diagnosing and monitoring TTP. Strong performance at critical low activity levels makes it a valuable tool in clinical practice. #TTP #hematology #ADAMTS13 #labmedicine #MedSky
www.jthjournal.org/article/S153...