Moritz Spangemacher

Superman Isn’t Trying to Be Political. We Just Have Real-Life Supervillains Now.

What a headline.

NY Times Ballot - Best Movies of the Century so far

„I have to admit that people who expand their consciousness by living instead of by taking chemicals usually come back with much more interesting reports of where they've been“
Ursula k. Le Guin

Drug Science, Policy and Law Screenshot of title page and abstract

Reframing Psychedelic Regulation: Tools, not Treatments

In this new article, we propose to regulate psychedelics as psychotherapeutic treatment tools rather than as treatments in their own right.

The use of anesthetics as treatment tools in surgery is a useful analogy.

Klaus Theweleit: "Diese Männer sind nicht zu Ende geboren" Wir leben in einer undenkbaren Zeit, sagt der Kulturwissenschaftler Klaus Theweleit. Soldatische Körper, leere Sprache, dreiste Lügen: Da entsteht eine neue Wirklichkeit.

Sehr lesenswert.

Reduced Brain Responsiveness to Emotional Stimuli With Escitalopram But Not Psilocybin Therapy for Depression | American Journal of Psychiatry Objective: Psilocybin is an emerging intervention for depression that may be at least as effective as selective serotonin reuptake inhibitors (SSRIs), but effects of the two treatments on the neural c...

🚨🚨New psychedelics paper out today! 🚨🚨

"Reduced Brain Responsiveness to Emotional Stimuli With Escitalopram But Not Psilocybin Therapy for Depression."

psychiatryonline.org/doi/10.1176/...
🧵⬇️

Opinion | What Kennedy Gets Right, And Wrong, About Antidepressants (Gift Article) Harm from these drugs is real. Let’s not cede the conversation to Kennedy.

My opinion piece in today’s @nytimes.com . I discuss how clinical neglect of medication-related harms has made RFK Jr’s stance on antidepressants appealing to so many and moving the public conversation in a productive direction requires us to remedy this neglect.

www.nytimes.com/2025/05/03/o...

Cortical neurons imaged by immunofluorescence

Research is investigating the medicinal applications of #psilocybin, with studies showing how #psychedelics can promote neuronal plasticity.

This ‘fundamental’ study into the effects of #psilocin on human neurons: buff.ly/f7cNemV

Safety and Efficacy of Repeated Low-Dose LSD for ADHD Treatment in Adults This double-blind, placebo-controlled randomized clinical trial determines the safety and efficacy of repeated low doses of lysergic acid diethylamide (LSD) in reducing attention-deficit/hyperactivity...

Another null result psychedelic trial. This time looking at LSD microdosing for ADHD. Most interesting is the detail showing most subjects in LSD group correctly guessed they got the psychedelic. BUT their benefits still mostly matched the placebo group.

Acute Effects and Pharmacokinetics of LSD after Paroxetine or Placebo Pre‐Administration in a Randomized, Double‐Blind, Cross‐Over Phase I Trial Psychedelics, such as psilocybin and lysergic acid diethylamide (LSD), are being investigated for the treatment of depressive and anxiety disorders, for which concomitant treatment with selective ser...

A recent study suggests that no dose adjustment of #LSD is necessary in the presence of an SSRI that inhibits CYP2D6. #psychedelics ascpt.onlinelibrary.wiley.com/doi/10.1002/...

Schluss mit dem Angriff auf NGOs und Medien! Keine Zensur durch die CDU! Nur einen Tag nach der Wahl hat die CDU/CSU-Fraktion eine Anfrage eingereicht, die gezielt NGOs und kritische Medien ins Visier nimmt. Einen Tag zuvor nannte Friedrich Merz Demonstranten gegen Rechts ...

This cause is close to my heart - please sign: weact.campact.de/petitions/sc...

Wir alle, Robert, wir alle

Wenig überraschend ist die größte inhaltliche Übereinstimmung der CDU mit einer anderen Partei, die, mit der AfD. Das macht gemeinsames Abstimmen natürlich mindestens verlockend und lässt es ganz natürlich erscheinen.
www.spiegel.de/politik/wahl...

Suicide of a patient shortly after psilocybin-assisted psychedelic therapy: A case report

First suicide in legal PAT, in Switzerland (first known case out of around 2000). History of delusions could be a red flag, not clear what the previous delusions and how psychosis-like they were. Thanks to the team for publishing this. www.sciencedirect.com/science/arti...

THE 25 BEST FILMS OF 2024

A video countdown

vimeo.com/1046284152

Glad to be at #ACNP2024 in Phoenix!
On Monday, I will be presenting the results of our episode trial in the session „Psychedelic-assisted Psychotherapy: From preclinical mechanisms to clinical applications“
alongside @fredbarrettphd.bsky.social, @kellietamashiro.bsky.social and Jennifer Mitchell.