Jose A. Seoane

What makes HR+ breast cancer tumors immune-cold?
New work shows how ER signaling hijacks LCOR, suppressing tumor immunogenicity.
Our PI @seoaneja.bsky.social participates on this study led by @tceliaterrassa.bsky.social, uncovering a target to sensitize tumors to ICB. www.jci.org/articles/vie...

With the start of our new study trying to find causes of bowel cancer in young people hitting the headlines today: www.bbc.co.uk/news/article... I'm so glad to see bold efforts to raise awareness, like this giant 5x3m poster on the Croydon station platform I pass by on my to the lab each day

Century-old tumours could reveal why more young people are getting bowel cancer - BBC News Bowel cancer in people under the age of 50 is increasing worldwide and scientists are striving to find out why.

Read about our plans to analyse the century long archive at St Mark's Hospital to understand why more young people are being diagnosed with bowel cancer @trevorgraham.bsky.social

www-bbc-co-uk.cdn.ampproject.org/c/s/www.bbc....

🚀 Ready to take your career to the next level❓

8–10 fully funded PhD fellowships now open for Life Sciences & Medical students!
Apply now and be the next to turn cancer discoveries into cures  👉 https://linke.to/PhDfellowships25_VHIO

📅 Deadline: 28 November
#SOMMVHIO @cerca.cat

Wellcome Connecting Science Cancer Genomic Epidemiology 2026 Course dates: 16-18 February Location: Wellcome Genome Campus, UK Application deadline: 3 November 2025 Apply now Image description: A group of course participants seated in a classroom. A speaker is standing at the front of the room, holding a microphone, and is addressing the room.

Are you a cancer scientist looking to strengthen your genomics epidemiology skills and knowledge?

Join experts at our #CancerEpi2026 course to transform your understanding of cancer causes and prevention.

🗓️ 16-18 February 2026
Apply by 3 November

📎bit.ly/41mRDnD

#OncSky #GeneSky 🧪🖥️🧬

Meet our exceptional training team for #CancerEpi2026 💫

Field experts will guide you through how to use the best genomics tools and approaches to detect cancer mutations.

🗓️ 16-18 February 2026
Apply by 3 November - bursaries available

📎 bit.ly/41mRDnD
#OncSky #GeneSky #CancerSky 🧪🖥️🧬

Last week, pre-doctoral researchers @juanravm.bsky.social and @mariabuxi.bsky.social attended #CCEsumschool25 to showcase some of our group's research 👏🏼
Thanks to @vhio.bsky.social and @cancercoreeurope.bsky.social for this valuable opportunity for the next generation of cancer researchers 🔬

Fluctuating DNA methylation tracks cancer evolution at clinical scale - Nature Cancer evolutionary dynamics are quantitatively inferred using a method, EVOFLUx, applied to fluctuating DNA methylation.

Studying cancer evolution needs multi-region or single cell seq for phylogenetics, right? Amazingly (I think!) we found single-sample bulk methylation suffices, via analysis of "fluctuating methylation". In @nature.com today led by brilliant @calumgabbutt.bsky.social www.nature.com/articles/s41...

Un algoritmo epigenético rastrea el origen del cáncer y predice su progresión Un equipo científico hispano-británico halla una 'caja negra' del cáncer que puede ayudar a desvelar la procedencia de los tumores y anticipar su evolución

Un algoritmo epigenético rastrea el origen del cáncer y predice su progresión

@jengreitz.bsky.social l & my lab want to co-hire a computational biologist/biostatistician with project management expertise to help map the regulatory code of the human genome and discover genetic mechanisms of disease.

Details below
careersearch.stanford.edu/jobs/computa...

Plz RT

Are you looking for a statistics/ML postdoc? Come to work with @antonis02.bsky.social and me in the NEMO study, an international collaboration aiming to detect ovarian cancer earlier through cutting-edge multi-omics, funded by the Alliance for Cancer Early Detection.
www.cam.ac.uk/jobs/researc...

📢 We have an open position at University of Geneva for a PhD student with CS/Math/Physics background to study adaptive immune responses using deep learning. If interested please contact me directly!

2025-040-01 Bioinformatics Scientist - VHIO Under the leadership of Josep Tabernero, VHIO is an internationally recognized cancer center. Its multidisciplinary, collaborative model drives scientific progress and innovative cancer treatments.

We are hiring!

We are searching for a motivated bioinformatics scientist interested in joining our team!

Apply below:

jobs.vhio.net/jobs/6203915...

Atul Butte died yesterday.
The world lost a giant.
A big bear of a man.
With a huge smile.
With love for everyone.
With energy that could power a room.
I loved everything about Atul.
I loved how he was always happy.
I loved how excited he was about science and helping people.

Reminder that the MSCA postdoctoral program exists. If you have a PhD and want to work in a European lab, you have until September to apply. Just contact them now.

ec.europa.eu/info/funding...

I have an opportunity to hire a staff scientist for my lab. Looking for someone with outstanding skillset in ML/statistics, genomics applications; interest in mentoring, strong publication record, PD experience required.

Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.

Our work on lineage tracing with somatic epimutations is finally out in @nature.com!

Check out the thread by @larsplus.bsky.social below.

EPI-clone is a revolutionary technique for lineage tracing and it will immediately impact how we trace clones everywhere.

Detailed protocols coming out soon!

🚨 Exciting Opportunity ‼️ The #VHIO Undergraduate International Computational Oncology Award is now OPEN 🚀

Join a one-month stay at VHIO’s computational oncology labs & contribute to cutting-edge cancer research!

Apply 👉 https://linke.to/VHIOUndergraduate25 📅 Deadline: May 23rd

#SOMMVHIO #CRISVHIO

🔬Exposomal determinants of non-genetic plasticity in tumor initiation.

✍️ Davide Carra, Silvana C.E. Maas, @seoaneja.bsky.social, @direnaac.bsky.social

📰 @cp-trendscancer.bsky.social 

Read more here 🔗 https://shorturl.at/CaicQ

📌 DOI: https://doi.org/10.1016/j.trecan.2025.01.010

#IRBScience 🧪

Excited to share our perspective led by @davidecarra.bsky.social with @silvanamaas.bsky.social & @seoaneja.bsky.social on how non-genetic #plasticity rewires epithelial cells and their stromal/immune/microbial contextures to fuel #cancer initiation, linking exposomal histories with disease fates ⬇️

📢#JOBOFFER: Junior Group Leader in Computational Cancer Biomedicine to establish an independent research group

We seek a talented scientist with expertise in:
• Bioinformatics
• AI
• Multi-omics data integration

📅 Deadline April 14

👉https://f.mtr.cool/tyfiexzxuo

Postdoctoral fellow - Saez-Rodriguez Group Your group Saez-Rodriguez Research Group Your supervisor Julio Saez-Rodriguez Your role As a postdoctoral fellow in the Saez Rodriguez group, you will develop and apply computational methods and tools...

Post-doc opening to join our lab @ebi.embl.org to develop&apply #bioinformatics and #machine-learning methods to study intra-/extra cellular networks to extract disease mechanisms from #single-cell and #spatial multiomic data - please share 🙏 : embl.wd103.myworkdayjobs.com/EMBL/job/Hin...

Ultra-processed food? Forever chemicals? Declining birth rates? What’s behind rising cancer in the under-50s? Research into the disease has never been more far-reaching, but there is little consensus as to what is causing the rocketing rates of diagnosis in young adults

Rates of #cancer in #young #adults have risen dramatically in recent years - as discussed in this article..

We urgently need to invest in #research 🧪 on early-onset cancers to understand - why?

www.theguardian.com/science/2025...

2024-081-01 Junior Group Leader - VHIO Under the leadership of Josep Tabernero, VHIO is an internationally recognized cancer center. Its multidisciplinary, collaborative model drives scientific progress and innovative cancer treatments.

Open call for a Junior Group Leader position in #ComputationalOncology at Vall d'Hebron Institute of Oncology (VHIO) @vhio.bsky.social.

See details below and consider applying jobs.vhio.net/en/jobs/5412... #CancerResearch

Now online in Cancer Discovery: Ancestral Differences in Anti-Cancer Treatment Efficacy and Their Underlying Genomic and Molecular Alterations - by Mei Luo, Jingwen Yang, Gordon Mills, Eytan Ruppin, Leng Han, and colleagues doi.org/10.1158/2159...

Let the data talk: embrace exploratory research Open-ended research is essential to building solid hypotheses in the social sciences — without it, even the best-planned analyses can fail.

www.nature.com/articles/d41...

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