More than 2 decades ago the PINK1 protein was found to be linked to Parkinson's disease, but its structure and how it was activated was not known. Until @science.org today. A triumph for cryo-EM and structural biology, introducing new targets for drug intervention.
www.science.org/doi/10.1126/...
13.03.2025 23:19 — 👍 395 🔁 84 💬 4 📌 5
Section through the 3D cryoET map of V-ATPase embedded in synaptic vesicle membrane at 17 Å resolution, as published in PNAS recently.
Oh my. This is just gorgeous from Misha Kudryashev's lab (I don't think he's here yet?). Love to see it. V ATPase resolved directly in synaptic vesicles 🤤 Lots of other neat observations in there also. Congrats to all involved! www.pnas.org/doi/10.1073/...
02.12.2024 04:30 — 👍 135 🔁 31 💬 2 📌 2
In today's Nature: A ‘Wikipedia for cells’
www.nature.com/articles/d41...
www.nature.com/immersive/d4...
20.11.2024 16:51 — 👍 117 🔁 27 💬 0 📌 2
Here I am, hope this app is better than twitter
13.11.2024 22:25 — 👍 1 🔁 0 💬 1 📌 0
Medicinal chemistry lab @IKCU, Faculty of Pharmacy, Izmir.
Drug discovery studies; design and synthesis new compounds as antileishmanial, antibacterial, anticancer, antiparasitic, FABPi, TYK2i
@istanbulluh.bsky.social
@huseyinkosker.bsky.social
It is said that there may be seeming disorder and yet no real disorder at all
Blizard Institute, QMUL, London. Working on inter-individual genetic and epigenetic variation of mammalian ribosomal DNA.
We are a free biomedical research literature discovery platform that uses machine learning and expert curation. Find out more https://biomed.news
Nature Aging is a thematic journal from the Nature Portfolio that serves the broad aging research community. Follows & posts ≠ endorsements.
pharmacist, PhD, researcher, medicinal chemist, drug discovery, neglected diseases, onehealth, Leismania
www.MitoWorld.org is a global mitochondria research, information and media hub which intends to be inclusive across the many mitochondria communities to promote mitochondria broadly to the public, to medicine, health advocates and education.
SMBE fosters communication among molecular evolutionists and advances the field.
🔗 smbe.org
💬 smbe2026.org • biosig.lab.uq.edu.au/strphy26
👥 @smbe-idea.bsky.social
📙 @molbioevol.bsky.social • @genomebiolevol.bsky.social
Senior Research Scientist at Stanford Bioengineering | Taking apart and building biology.🧪
Across many scientific disciplines, researchers in the Bernstein Network connect experimental approaches with theoretical models to explore brain function.
Offizieller Bluesky-Account der Uni Göttingen (ohne Unimedizin) • Bluesky account of University of Göttingen • http://uni-goettingen.de/impressum
Prof. at University of Cambridge @mrc-mbu.bsky.social; co-founder of Pretzeltx.com
Enjoying the little things in life — like the first flowers of spring, a good cup of cafezinho, and amino acid side chains fitting perfectly into a nice map.
Scientist, nature-lover, cyclist and climber in my free time
physician-scientist, author, editor
https://www.scripps.edu/faculty/topol/
Ground Truths https://erictopol.substack.com
SUPER AGERS https://www.simonandschuster.com/books/Super-Agers/Eric-Topol/9781668067666
RNA modifications, antibiotic tolerance, bacterial stress, non coding RNAs, Vibrio cholerae.
Institut Pasteur & EGM (IBPC, CNRS)
Mitochondrial Research Group @newcastleuni.bsky.social
Working together to improve our understanding of mitochondrial function in health and disease
#Mitochondria #MitoResearch #Science #Genetics #BiomedicalResearch #TranslationalMedicine #MedicalScience
MitoCAMB brings together a team of clinical researchers focused on mitochondrial and neurodegenerative disease translational research.
mitocamb.medschl.cam.ac.uk
(Photo: Florian Klimm)
The European Molecular Biology Laboratory drives visionary basic research and technology development in the life sciences. www.embl.org
