Leah Greenspan

Attention all NAVBO Members:

Check out “The Vascular Network” - NAVBO’s brand-new members-only social media platform is active!! 🚀

Stay connected and engaged with the vascular biology community and all things at NAVBO!

Check out here for more👉 navbo.junolive.com/main/home

Development's Pathway to Independence programme: meet the 2025 fellows - the Node Earlier in 2025, we welcomed our third cohort of Development's Pathway to Independence (PI) fellows - researchers whom we will be supporting as they

Meet Development’s 2025 Pathway to Independence (PI) fellows

In a series of interviews published in @dev-journal.bsky.social, we learn more about each fellow’s career path, research interests and aspirations when they start their own lab.

thenode.biologists.com/developments...

Society for Developmental Biology logo Ethel Browne Harvey Postdoctoral Seminar Series SDB Postdoc Members -- Apply Today Application Deadline August 1, 2025 QR Code to EBH Seminar website

#DevBio #Postdocs! Abstracts are being accepted for speakers in the 2025-2026 Ethel Browne Harvey Postdoctoral Seminar Series. SDB postdoctoral members are eligible to apply. Deadline: August 1. #SDBPostdocSeminar bit.ly/3x1ptgb

Over a decade in the making but excited to have helped bring this paper over the finish line. We generated an endothelial ribotag transgenic line and profiled endothelial cells in larvae and adult organs of zebrafish #zebrafish #DevBio 🧪
Check out our publication: link.springer.com/article/10.1...

DaniocellDesktop logo, depicting a fish on a laptop screen.

If you love Daniocell, but wish it could generate analyses specific to YOUR genes & cell types of interest, check out DaniocellDesktop - a new point-and-click app for Mac and Windows that enables reanalysis of the Daniocell data without programming: daniocell.nichd.nih.gov/desktop/ (1/4)

Attention all NAVBO Members:

Check out “The Vascular Network” - NAVBO’s brand-new members only social media platform.
Launch Date: June 12th 2025

Use it to stay connected and engaged with the vascular biology community and all things NAVBO!

Get access here: navbo.junolive.com/main/home

Check out the latest microscopy preprints including our recent favorite tool (LUCID) from #WeinsteinLab 🔥

🔗 to preprint: www.biorxiv.org/content/10.1...

Dorsal view of adult zebrafish showing the lymphatic system in the brain and scales. Appearing in three different color combinations.

High-resolution optical imaging of the meninges within the brain of an adult zebrafish. Credit to @zebrafish007.bsky.social & #WeinsteinLab. #ZebrafishZunday 🧪

Close up of a zebrafish larval body showing depth-coded epigenetic reporter signal in the liver tissues of a ppat mutant zebrafish

It's been a long time coming and I'm super excited to share our new preprint is out: "A novel transgenic reporter to study vertebrate epigenetics". We generated a zebrafish epigenetic reporter and found a fatty liver disease mutant with weird epigenetic phenotypes 👇

www.biorxiv.org/content/10.1...

An optogenetic toolkit for robust activation of FGF, BMP, and Nodal signaling in zebrafish Cell signaling regulates a wide range of biological processes including development, homeostasis, and disease. Accessible technologies to precisely manipulate signaling have important applications in ...

Happy to share a new preprint from my lab! We characterize the on/off kinetics, light dosage-dependence, and more for a suite of optogenetic signaling activators in zebrafish embryos 💡 www.biorxiv.org/content/10.1...

Amazing news Isabella!!! Congratulations!

Switching fields to #zebrafish? Wanting to become an expert in zebrafish research? Check-out the @mblscience.bsky.social 2025 Zebrafish Development & Genetics course – a fantastic opportunity to learn from leaders in the field!

Application deadline: March 13

www.mbl.edu/education/ad...

Society for Developmental Biology logo Society for Developmental Biology 2025 Award Winners Edwin G. Conklin Medal Headshot of Blanche Capel Blanche Capel, Duke University Developmental Biology-Society for Developmental Biology Lifetime Achievement Award Headshot of Billie Swalla Billie Swalla, University of Washington Viktor Hamburger Outstanding Educator Prize Headshot of Erica Crespi Erica Crespi, Washington State University Elizabeth D. Hay New Investigator Award Headshot of Mubarek Syed Mubarak Syed, The University of New Mexico Society for Developmental Biology Trainee Science Communication Award Headshot of Joaquin Navajas Acedo Joaquin Navajas Acedo, Biozentrum at University of Basel

Congrats to the 2025 SDB Award Winners!
Conklin Medal: Blanche Capel
DB-SDB Lifetime Achievement Award: Billie Swalla
Hamburger Outstanding Educator Prize: Erica Crespi
Hay New Investigator Award: Mubarak Syed
SDB Trainee Science Communication Award: Joaquin Navajas Acedo
bit.ly/4bcrFap

#ZebrafishCareers 🇺🇸 (Lab Manager)

Looking to enhance your timeline for 2025? Check out our Starter Pack of outstanding Group Leaders and Scientists from the #zebrafish community! #WomenInScience go.bsky.app/4BegEjv 🧪

Pathway to independence: a new initiative supporting postdocs on the job market

Apply for our Pathway to Independence programme, a scheme supporting postdocs going on the job market in 2025 with training, mentorship, profile-raising and networking opportunities. Apply by 31 Jan 2025: https://buff.ly/3VJGgDC

Clutch of zebrafish embryos neatly arranged. Credit to Dr. Mario Mendieta.

Merry Fishmas to all, and to all a good feeding! Thanks to all that are taking care of our fish this holiday season 🙏

A highly detailed gray image of the dorsal view of a zebrafish head pointing to the left with two large black eyes on either side. A complex network of magenta blood vessels look like tangled spaghetti in the center (brain region) of the image. There are dozens of ameba-shaped green cells around the brain blood vessels and a few well-defined green lymphatic vessels on either side of the head. Protruding from the skin on each side of the head, to the right (posterior) to the eye, there are three volcano-like structures with long, transparent, hair-like projections. These are hair cells that the fish uses to sense changes in water flow.

Looking down at the head of a transgenic 17-day-old #zebrafish, blood vessels in magenta, lymphatic vessels in green. Extended depth of focus #WeinsteinLab 🧪🔬

Zebrafish glial-vascular interactions progressively expand over the course of brain development Glial-vascular interactions are critical for the formation and maintenance of brain blood vessels and the blood-brain barrier (BBB) in mammals, but their role in the zebrafish BBB remains unclear. Using three glial gene promoters—gfap, glast, and glastini (a truncated glast)—we explored glial-vascular development in zebrafish. Sparse labeling showed fewer glial-vascular interactions at early stages, with glial coverage and contact area increasing with age. Stable transgenic lines for glast and glastini revealed similar developmental increases, starting at ∼30% coverage at 3 days post-fertilization (dpf) and peaking at ∼60% by 10 dpf, and consistently higher glial coverage in the forebrain and midbrain than in the hindbrain.

And somehow I missed it going live last week 😂 - our #zebrafish glial-vascular paper is available for those finterested! One of the best ways to end 2024 as a #newPI www.cell.com/iscience/ful...

Image of the larval zebrafish nervous system. Color-coded for depth.

Development of the nervous system in a #zebrafish larva. Credit to Dr. Nathan Martin of @plavickilab.bsky.social. #ZebrafishZunday 🧪

Let your timeline shine with these outstanding #WomenInScience! 🧪 #zebrafish go.bsky.app/4BegEjv

Thanks so much!

Hi Edan, can you please add me to the list. Thanks!

And zebrafish are more closely related to zebras than to sharks! #ZebrafishFunFacts 🧪

This is a fantastic program and I highly recommend anyone going on the faculty job market to apply! As part of the first cohort I’m happy to chat about the program. Feel free to DM me if you want to learn more.

Dissected & PFA fixed fli1a_GFP heart. Leica SP8 confocal microscope, 25x HC Fluotar Objective, many stacks and stitched tiles. Description from Aaron Scott

Vasculature in the adult zebrafish heart. Credit to Dr. Aaron Scott. #ZebrafishZunday 🧪

Check out #ZebrafishZunday every Sunday for fintastic fish #sciart! 🧪

Graphical abstract of the study

Out now in Dev Cell! scRNAseq trajectories describe the cascade of gene expression as cells differentiate, but turning them into a clear understanding of the underlying biology of a cell type's development remains challenging. authors.elsevier.com/c/1k9qj5Sx5g... (1/)

Thanks Neha! So glad you were able to attend and that you enjoyed the presentation 😊