Read our comment on the rise of ADP-ribose-Ubiquitin hybrid modification. It's been fun to see it grows :)
09.09.2025 11:34 — 👍 6 🔁 1 💬 0 📌 0
Identification of RNF114 as ADPr-Ub reader through non-hydrolysable ubiquitinated ADP-ribose - Nature Communications
Deltex E3s modify ADP-ribosylated targets with ubiquitin, creating a hybrid modification whose readers remains unknown. Here, the authors synthesise a non-hydrolysable probe that mimics the modificati...
An amazing paper from van der Heden and Ahel groups! They use clever chemistry to identify RNF114 as a dual ADP-ribose-Ubiquitin reader involved in the DNA damage response! Congratulations to first authors Max, @chatrin-c.bsky.social and Rishov. Happy to have a small contribution in this story
10.07.2025 10:44 — 👍 17 🔁 5 💬 0 📌 0
Senior Research Scientist at MRC-PPU, working in the lab of Yogesh Kulathu. Interested in ubiquitin, RBR ligases, innate immune signalling and heavy metal 🤘
Principal Group Leader at the Francis Crick Institute. DNA replication, cryo-EM and molecular mechanism.
A leading center for expert, compassionate cancer care and advanced research.
Appts: 877-442-3324 | http://dana-farber.org
Interested in mass spectrometry and the crosstalk of ADP-ribosylation and ubiquitylation during the DNA damage response.
We are interested in ADP-ribosylation, PARP1 signalling, proteomics, histone PTMs, protein engineering, the DNA damage response and aging
Max Planck Institute for Biology of Ageing, Cologne, Germany
Interested in Ubiquitin, Proteostasis and Signaling
Scientist at @mpibiochem.bsky.social
Alumnus of @mrclmb.bsky.social
Ubiquitin-like proteins and Development Lab @ CIC bioGUNE
Bilbao
Ubiquitin, SUMO, rare diseases, Drosophila, E3 ligases
https://www.rosabarriolab.es/
Opinions my own.
2024 BBSRC Fellow | University of Oxford | Junior Research Fellow at Linacre College | Investigating antibiotic resistance & tolerance, and better ways to kill pathogens 🧫
https://scholar.google.com/citations?hl=en&user=L2mEVzEAAAAJ
Professor and Chair of Cell Biology at harvardcellbio , all things ubiquitin, autophagy, protein/organelle quality control & proteomics (website:harper.hms.harvard.edu). Mostly posting from @harvardcellbio.bsky.social
Independent Research Group @ the Max Planck Institute for Multidisciplinary Sciences, Goettingen, Germany
@mpi-nat.bsky.social
We love ubiquitin, kinases, and good food.
Sir Henry Wellcome fellow studying macrophage migration and mechanobiology @UCL. BSc Biochemistry @Bristol. PhD Cancer Biology @CRUK Scotland Institute. 🏴
Cell lover by day, takeaway lover by night.
https://hoanganhle2602.wixsite.com/cellsandtheirwonders
Professor of Molecular Immunology at the University of Oxford.
Experiments & Math(s) to understand and exploit T cells.
Founder & Director of MatchBio Ltd
The Lechtenberg Lab at WEHI in Melbourne, Australia. Interested in all things ubiquitin, E3 ligases and structural biology.
The laboratory is investigating the role of ubiquitin system in cancer pathogenesis and response to treatment with ionising radiation.
Protein Biochemist at the University of Manchester researching #ubiquitin #ubl #PTMs in genome stability
GoodGymer | Runner | Dog owner
Marie Curie Postdoctoral fellow at Oxford with Emma Slack | Fulford JRF at Somerville College | Infection ecology, immune-pathogen interactions, and science outreach | she/her 🇨🇦
Associate Prof. at the Dunn School and Magdalen College, University of Oxford. The lab studies the molecular and cellular basis of bacterial pathogenesis.
Group leader & MRC CDA fellow at the Dunn School, Oxford. Cilia, motor proteins & intracellular organisation using cryo-EM/ET & cell biology. Run a co-lab with Anthony Roberts.
Postdoc in Carvalho lab, @Dunnshool.bsky.social Oxford, working on lipid droplet biogenesis and membrane proteins.
Don't take life too seriously - its your only one.
