A/Prof Sam Stehbens PhD (She/Her)'s Avatar

A/Prof Sam Stehbens PhD (She/Her)

@samstehbens.bsky.social

Everything microtubules, movement, and microscopy. ARC Future Fellow, lab head University of Queensland #CatsOfAcademia advoCATe. UCSF Wittmann lab alumni.

3,617 Followers  |  1,815 Following  |  403 Posts  |  Joined: 08.08.2023  |  2.3875

Latest posts by samstehbens.bsky.social on Bluesky

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Don’t miss it! πŸš€ MBoC Presents: The Next Generation of Cell Biology (Part 2)
πŸ—“οΈ Oct 30, 9am ET | FREE webinar

Hear from early career scientists on pH profiling, dynein adaptors, migration, chromatin & more.

πŸ”— Register: www.ascb.org/ascb-meeting... #ASCB #CellBiology

07.10.2025 12:30 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Structure and Function of the Cytoskeleton The cytoskeleton, a dynamic and intricate network of protein filaments, is found within the cytoplasm of all cells, from bacteria and archaea to complex eukaryotes. This essential cellular component …

Learn all things #cytoskeleton #research in an interdisciplinary environment at EMBO Workshop "Structure and Function of the Cytoskeleton" in Paris, FR, 7–10 April 2026.

Deadline: 20 December 2025

https://meetings.embo.org/event/26-cytoskeleton
#EMBOCytoskeletalFunction #EMBOevents #conference πŸ§ͺ

07.10.2025 15:35 β€” πŸ‘ 25    πŸ” 28    πŸ’¬ 0    πŸ“Œ 3

πŸ‘Translation πŸ‘dries up πŸ‘if you stop feeding πŸ‘the pipeline πŸ‘of discoveryπŸ‘

#NHMRCdraftStratergy #Ihavenotes #ValueFundamentalScience

06.10.2025 21:27 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
Why Basic Science Matters
YouTube video by UC San Francisco (UCSF) Why Basic Science Matters

#Discoveryscience matters- a nice video with some familiar faces from #UCSF @ctbatucsf.bsky.social
@ucsfbhhi.bsky.social

youtu.be/N9nMeCaW_Vg?...

07.10.2025 06:03 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

This is so disappointing. Fundamental **aka DISCOVERY ** science underpins training of the next generation of scientists, irrespective of if they go into translation labs or not. Failure to support it = turning off the tap. No discoveries, nothing to translate. Weak workforce #NHMRC

07.10.2025 01:12 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1
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Shout out to a freshly minted PhD from my team πŸ‘‰ @christanny.bsky.social who has presented several talks on my team’s behalf the last few months as I’ve been travelling. Watch this space for a new super star! πŸ’« #cytoskeleton

02.10.2025 10:32 β€” πŸ‘ 14    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧡...

01.10.2025 18:20 β€” πŸ‘ 219    πŸ” 68    πŸ’¬ 11    πŸ“Œ 18
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A mechanical origin for implantation defects in embryos from aged females Women over 35 experience a marked reduction in fertility. The origin of these fertility defects appears to reside in the implantation capacity of the embryo itself, but the mechanistic basis of this i...

First, check out my recent bioRxiv preprint w/ @oweinerlab.bsky.social: www.biorxiv.org/content/10.1...
We find contractility shifts the proportion of implantation-competent embryos from young and aged females. Keep reading this for more info!

01.10.2025 18:20 β€” πŸ‘ 32    πŸ” 8    πŸ’¬ 2    πŸ“Œ 1
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Who’s shaping the future of cell biology? 🌟 Find out at the MBoC 2025 Early Career Award Webinar (Part 1) β†’ Oct 7, 12–1 pm ET.

Free registration πŸ‘‰ www.ascb.org/ascb-meeting... #ASCB #CellBiology

30.09.2025 12:15 β€” πŸ‘ 1    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

I’m not sure as a community we **truely** acknowledged how powerful the #CellMigrationSeminarSeries series was at keeping us connected at such an uncertain time. Thank-you @ankita13jha.bsky.social @adamshellard.bsky.social @drjenmitchell.bsky.social & @simplythebex.bsky.social

29.09.2025 02:07 β€” πŸ‘ 19    πŸ” 10    πŸ’¬ 2    πŸ“Œ 0

I often wonder if I should post my cell migration lectures to you tube πŸ€”

29.09.2025 01:55 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0
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Cell Migration Seminars Cell Migration Seminars every Tuesday at 16:00 BST.

If anyone ever wants to brush up on a lot of cell migration concepts don't forget we have several wonderful scientists who have given talks previously in cell migration seminars. I find it so comforting to go look at old videos, maybe someone else who will do as well!!
youtube.com/@cellmigrati...

29.09.2025 01:48 β€” πŸ‘ 43    πŸ” 10    πŸ’¬ 1    πŸ“Œ 2
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A purpose built solution to Australia’s biomedical funding crisis….. release the #MRFF = invest in our future scientists & their discoveries. #DiscoveriesNeedDollars www.smh.com.au/politics/fed...

29.09.2025 01:51 β€” πŸ‘ 12    πŸ” 8    πŸ’¬ 1    πŸ“Œ 0

Proteomic analysis reveals fibroblast growth factor receptor substrate 2 as a hub for FGFR-driven cytoskeleton and cell junction regulation https://www.biorxiv.org/content/10.1101/2025.09.23.678042v1

26.09.2025 00:48 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Cover of "Fifty Shades of 'Jay'" with emails from Jeremy M. Berg to NIH Director Jayanta Bhattacharya.

Cover of "Fifty Shades of 'Jay'" with emails from Jeremy M. Berg to NIH Director Jayanta Bhattacharya.

All my emails to Director Bhattacharya now available...

jeremymberg.github.io/jeremyberg.g...

22.09.2025 17:08 β€” πŸ‘ 187    πŸ” 54    πŸ’¬ 12    πŸ“Œ 11
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EACR Goodbye Flat Biology in Germany was fun- reconnected with old UCSF crew. Learnt some amazing science and made some new friends. One of the best cancer conferences I have attended. (Looking forward to seeing my kitties at home!).

25.09.2025 13:12 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

On #worldcancerday it has been humbling to be surrounded by a truely impressive cohort of cancer scientists at @helloeacr.bsky.social β€˜s Goodbye flat biology conference. We need to keep investing in research to make sure we can create impact in this space.

24.09.2025 16:58 β€” πŸ‘ 9    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
U-ExM expanded HeLa cell stained with HAK-actin (orange) and DNA (blue).

U-ExM expanded HeLa cell stained with HAK-actin (orange) and DNA (blue).

HAK-actinβ„’: a new probe to label #actin in your expansion microscopy samples with a robust yet simple protocol.

Find out how HAK-actinβ„’ can help you achieve a bright actin staining in your ExM workflow: spirochrome.com/product/hak-...

Image credits: Olivier Mercey, UNIGE

19.09.2025 09:45 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 1    πŸ“Œ 2

Congrats to @errricpeterman.bsky.social on leading our latest paper now published in @jcellsci.bsky.social ! Eric found multiple roles for microtubules in tissue-resident macrophage homeostasis and function -- including in helping macrophages navigate around epithelial obstacles during wound repairπŸ‘‡

18.09.2025 16:21 β€” πŸ‘ 15    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0
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Description Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer.

Deadline 15th October. Get in touch if you have any questions.

Please repost!

More details:
www.imperial.ac.uk/jobs/search-...

18.09.2025 20:02 β€” πŸ‘ 30    πŸ” 35    πŸ’¬ 0    πŸ“Œ 3

Have you ever wondered how microtubules withstand and respond to mechanical stress in cells?

Here we show by in vitro reconstitution assays that MAP65-1 and PRC1 promote microtubule nucleation on existing lattices, especially on those with structural irregularities linked to mechanical stress.

16.09.2025 06:43 β€” πŸ‘ 10    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

SCHEPHERD--the bioelectric cell herding platform built for YOU. Single cells, monolayers, organoids--this herds them all + new tricks. Plz try it-- we will *give* you parts! Teaser here of a steering a single cell. GS Yubin Lin's lifeblood with J. Yodh on piano; Celeste R. and Paul K. Thread 1/N

17.09.2025 17:20 β€” πŸ‘ 60    πŸ” 26    πŸ’¬ 4    πŸ“Œ 4
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You asked for it! We delivered Quack-O-Grams to our members of Congress urging them to #ImpeachRFK, and get that Quack out of office!

There's still time for you to get in on this fluffy, feathery action: Send your own duck at zurl.co/W1ZnB and keep the momentum going! πŸ¦†

17.09.2025 21:32 β€” πŸ‘ 1007    πŸ” 354    πŸ’¬ 30    πŸ“Œ 63
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🚨Great News!🚨
Our latest preprint is now live on bioRxiv!
We show that MAP65-1 and PRC1 facilitate microtubule nucleation on pre-existing lattices, particularly at sites with structural defects associated with mechanical stress.

Congrats @marianattom.bsky.social

www.biorxiv.org/content/10.1...

16.09.2025 11:39 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

And now I wonder….

16.09.2025 03:56 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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The proliferation rate paradox in antimitotic chemotherapy | Molecular Biology of the Cell Cytotoxic cancer chemotherapy drugs are believed to gain selectivity by targeting cells that proliferate rapidly. However, the proliferation rate is low in many chemosensitive human cancers, and it is...

www.molbiolcell.org/doi/full/10....

14.09.2025 23:29 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

I’ll use this opportunity to highlight Tim Mitchison’s article in #MBoC

It’s not all about targeting cell division! #microtubule #MTA #cytoskeleton

14.09.2025 23:28 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Murine centrosomal proteins with non-mitotic cytoskeletal side gigs. The numbers are SDS-PAGE migration values converted to estimated "kiloDaltons". #proteomics

13.09.2025 11:32 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
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πŸŽ‰New Paper DropπŸŽ‰ We just uploaded our latest findings on bioRxiv!

We report the identification of the limits of microtubule self-repair and how microtubule integrity is maintained under mechanical load.

Congratulations @bucklingmt.bsky.social

www.biorxiv.org/content/10.1...

14.09.2025 08:11 β€” πŸ‘ 14    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1

Love a good tutorial …

14.09.2025 23:10 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1

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