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Pierre Grognet

@pierregrognet.bsky.social

Assistant Professor, MCU HDR, Univ. Paris-Saclay / I2BC (Epi)genetics, Podospora 🍄 Member of @SFgenetique.bsky.social

530 Followers  |  563 Following  |  45 Posts  |  Joined: 04.10.2023  |  2.1587

Latest posts by pierregrognet.bsky.social on Bluesky

@tobybarilbio.bsky.social and I are very excited to release MycoMobilome! A very extensive effort to discover, QC and annotate TEs across the fungal kingdom.

👉 Ready-to-use for your own genome with a simple tutorial!
👉 Metadata about TEs discovered in your genome!
👉 Contribute and get recognition!

29.10.2025 16:32 — 👍 42    🔁 15    💬 0    📌 0
Equipe Courret – Institute for Integrative Biology of the Cell

I'm thrilled to announce that I’m opening my own research team in the Department of Genome Biology at I2BC @i2bcparissaclay.bsky.social ! #ATIP-Avenir
Very excited to start this new adventure! www.i2bc.paris-saclay.fr/equipe-intra...

24.10.2025 15:39 — 👍 29    🔁 6    💬 5    📌 3

Sorry Batrachochytrium

17.10.2025 18:54 — 👍 1    🔁 0    💬 1    📌 0

Batrachochydridium and frogs
Pseudogymnoascus and bats
Ophiocordyceps and ants
How long do you have? ;)

17.10.2025 18:52 — 👍 1    🔁 0    💬 1    📌 0
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These stinkbugs coat their eggs in fungi to protect them from parasitic wasps An unusual relationship could shed light on how insects choose their partners

How to protect your children by covering them in fungus (if you’re a stinkbug) www.science.org/content/arti...

16.10.2025 18:25 — 👍 38    🔁 10    💬 0    📌 0
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Fungal #GenomeSize variation is largely driven by TEs & lineage-specific genome defenses. @tbadet.bsky.social & @danielcroll.bsky.social show that presence/absence of RIP mutation systems influences #genome architecture, identifying a likely novel defense mechanism @plosbiology.org 🧪 plos.io/4hcC5tx

16.10.2025 12:55 — 👍 6    🔁 5    💬 0    📌 0
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BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

15.10.2025 12:22 — 👍 489    🔁 186    💬 56    📌 60
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Why does the naked mole rat have the longest lifespan of any rodent, nearly 40 years?
A 30-year long mystery unraveled @ScienceMagazine today!
Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressing inflammation
www.science.org/doi/10.1126/...

09.10.2025 18:06 — 👍 347    🔁 103    💬 12    📌 20
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Les champignons, les bons🍄‍🟫🍺🥖, les brutes 🍄🍄‍🟫 et les truands 🍄‍🟫☘️c’est ce week-end ! @inrae-bioger.bsky.social @spsplantsciences.bsky.social #Phytopathologie mais aussi
#InteractionsMicrobiennes
#MetabolitesSpecialisés #ANR-FRiPPon

02.10.2025 16:59 — 👍 12    🔁 5    💬 0    📌 0
People arm in arm while drinking coffee and holding papers, with text: Why scientists should take more coffee breaks.

People arm in arm while drinking coffee and holding papers, with text: Why scientists should take more coffee breaks.

Here's a reminder on #InternationalCoffeeDay: It's OK to take a (coffee) break. ☕

"It’s ... helpful to have a venue to share the day-to-day ups and downs of life as a grad student," a #PhD student wrote in this 2019 #ScienceWorkingLife. https://scim.ag/4nvLTBb

01.10.2025 16:24 — 👍 70    🔁 23    💬 1    📌 2
The recombination frequency (cM/Mb) along chromosome 4 of A. thaliana (female meiosis). 

In full hybrids (grey), where polymorphism is distributed all along chromosomes, most crossovers occur in the regions surrounding the Centromere (Cen), and very few at chromosome ends (Tel: telomeres). 

In lines where polymorphism is restricted to chromosome ends (purple), the local recombination rate increases drastically, at the expense of the non-polymorphic regions (yellow).

The recombination frequency (cM/Mb) along chromosome 4 of A. thaliana (female meiosis). In full hybrids (grey), where polymorphism is distributed all along chromosomes, most crossovers occur in the regions surrounding the Centromere (Cen), and very few at chromosome ends (Tel: telomeres). In lines where polymorphism is restricted to chromosome ends (purple), the local recombination rate increases drastically, at the expense of the non-polymorphic regions (yellow).

🚨 First pre-print from my team !!

TL;DR: presence of polymorphism (sequence differences between the homologous chromosomes) can *increase* the local rate of recombination in Arabidopsis thaliana, turning cold regions of the genome hot (purple v. grey) !

01.10.2025 08:31 — 👍 45    🔁 16    💬 3    📌 5
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Beaucoup de champignons parasites sont à la fois Dr Jekyll et Mr Hyde

Beaucoup de champignons parasites sont à la fois Dr Jekyll et Mr Hyde

La biologiste Audrey Dussutour alerte sur la menace fongique mondiale, mal prise en compte, aggravée par le commerce international et le réchauffement climatique

28.09.2025 21:02 — 👍 22    🔁 16    💬 2    📌 1
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Les marchés publics de voyagistes - Contributions - 2025 - Aidez-nous à enrichir notre programme de travail - Plateforme de participation de la Cour des Comptes Corps de la contributionLes administrations et opérateurs publics, notamment ceux de l'enseignement supérieur et de la recherche, fond appel à des agences de voyage (FCM, TravelPlanet…) pour l'hôtelle...

Vous pouvez soutenir ma proposition à la Cour des Comptes d'examiner les marchés publics de voyagistes, notamment dans l'ESR :
participationcitoyenne.ccomptes.fr/processes/co...

25.09.2025 10:28 — 👍 85    🔁 78    💬 8    📌 4
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Our department of Plant Molecular Biology at the University of Lausanne @unil.bsky.social is recruiting a Tenure-Track Assistant Professor in the field of Plant-Organism Interactions 🌱🐛🦠🍄! Application before November 30, 2025. See the official job ad for more details: tinyurl.com/mtxdcz6p

17.09.2025 20:00 — 👍 42    🔁 54    💬 1    📌 1
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Lediga jobb vid Stockholms universitet Jobb

We have several open positions in my group, funded from the ERC Grant on the Early Sequestered Germline of Fungi. We search broadly for applicants at both PhD and master-level, with a dedicated interest in fungal evolutionary biology. Please forward and RT!
Find the positions here: su.varbi.com

07.09.2025 13:13 — 👍 51    🔁 52    💬 0    📌 1

Biology never ceases to amaze!

03.09.2025 20:37 — 👍 26    🔁 8    💬 0    📌 0
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Today we had the chance to welcome Cécile Lorrain @ccilelorrain.bsky.social at the I2BC @i2bcparissaclay.bsky.social
Thanks for the great talk and very interesting discussion!

01.09.2025 15:33 — 👍 8    🔁 1    💬 0    📌 0

Homology-mediated transformation of frog-killing fungus Batrachochytrium dendrobatidis illuminates chytrid development and pathogenesis https://www.biorxiv.org/content/10.1101/2025.08.29.673073v1

31.08.2025 20:30 — 👍 3    🔁 2    💬 0    📌 0
Cover of Mycology Laboratory Manual

Cover of Mycology Laboratory Manual

The Pennsylvania Alliance for Design of Open Textbooks (PA-ADOPT) is pleased to announce our 19th free and open eTextbook: "Mycology Laboratory Manual" by Laura Ramos-Sepulveda, Professor of Biology at @millersvilleuni.bsky.social paadopt.org/bookshelf/my... #HigherEd #OER #EduSky #AcademicSky

29.08.2025 20:07 — 👍 6    🔁 2    💬 1    📌 0

The fun would be watching Chump's reaction to it. 🤯

#ReleaseTheEPSTEIN_Files

29.08.2025 20:03 — 👍 15875    🔁 2458    💬 470    📌 83

Congrats!

15.08.2025 19:21 — 👍 1    🔁 0    💬 0    📌 0
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Early germline sequestration in a basidiomycete fungus In sexual organisms, inheritance of new mutations is highly dependent on the timing of germline definition. Here, we used the fairy ring–forming fungus Marasmius oreades to challenge the general assum...

It started as a master thesis project by Markus Hiltunen, and ended up in this publication in Science. What a fun project to work on! Thanks Markus - and all other coauthors, too, for a great team work! www.science.org/doi/10.1126/...

14.08.2025 19:54 — 👍 50    🔁 25    💬 2    📌 2

So intriguing!

15.08.2025 19:13 — 👍 1    🔁 0    💬 0    📌 0
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Coprophilous fungi in the search for new antimicrobials and other beneficial natural products Covering: up to 2025Microbial interactions involve complex processes shaped by their ecological contexts. Herbivore animal dung denotes an interesting ecological niche for the study of interorganism c...

pubs.rsc.org/en/content/a...
Our new review on the secondary metabolites of coprophilous fungi has just been published by Natural Product Reports. Thanks for funding from the @humboldt-foundation.de foundation.de, the @dfg.de & the @daadworldwide.bsky.social Congrats to all coauthors!

09.08.2025 08:39 — 👍 14    🔁 7    💬 1    📌 0
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Un article de synthèse (en français !!!) sur les communautés fongiques des sols forestiers face aux changements climatiques publié dans les Comptes Rendus Biologie de l'Académie des Sciences :
comptes-rendus.academie-sciences.fr/biologies/ar...

30.07.2025 16:28 — 👍 18    🔁 9    💬 0    📌 0

Est-ce que cette pétition aura autant de succès que celle contre la loi Duplomb ?

27.07.2025 21:16 — 👍 17    🔁 10    💬 2    📌 1
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Cluster de maladie de Charcot en Savoie : 10 années d’enquête avant d'identifier le coupable

Cluster de maladie de Charcot en Savoie : 10 années d’enquête avant d'identifier le coupable

"On voyait le nombre de cas augmenter tous les ans, c’était terrifiant"

27.07.2025 18:32 — 👍 5    🔁 3    💬 0    📌 0
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"Il suffit de toutes petites perturbations sur la route, comme une irrégularité sur le bitume ou un moment d'inattention du chauffeur pour qu'une vague de trafic se forme"
👉 https://l.sciencesetavenir.fr/Dpw

26.07.2025 12:16 — 👍 4    🔁 3    💬 0    📌 0
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The #Yeast2025 conference is now FULL with around 500 attendees! 🎉 - Thank you to everyone who registered.

We’re excited to introduce new sessions:
🧠 ERC Grant Career Paths @erc.europa.eu
🤝 Meet the Industry
📝 Meet the Editors

We can’t wait to welcome you!
premc.org/yeast2025/

04.04.2025 07:02 — 👍 11    🔁 2    💬 0    📌 0
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🏖️Our July issue's out!
Cover: Droplets in meiotic crossovers

👉🏼Comment on #Alzheimers
👉🏼Reviews on #aging and #EndoplasmicReticulum -associated degradation
🔬 #BreastCancer #autophagy #neurodegeneration #amnion #chromatin #meiosis #PhaseSeparation #healthspan & more!
www.nature.com/ncb/volumes/...

18.07.2025 20:09 — 👍 14    🔁 2    💬 1    📌 0

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