Prof Anthony Isles's Avatar

Prof Anthony Isles

@profantisles.bsky.social

#Neuroscience 🧠 | #ImprintedGenes 🧬 | #preclinical models 🐭🧫| MURIDAE lead @mrcmousenetwork.bsky.social | Cardiff University | posting in a personal capacity, mostly about science https://profiles.cardiff.ac.uk/staff/islesar1

788 Followers  |  735 Following  |  280 Posts  |  Joined: 25.09.2023  |  1.6857

Latest posts by profantisles.bsky.social on Bluesky

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Cardiff folk πŸ‘‡

16.02.2026 13:11 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Library support enables Royal Society open access shift - Research Professional News Eight subscription journals go fully OA during 2026 through subscribe to open model

Library support enables Royal Society open access shift.

Eight subscription journals go fully OA during 2026 through subscribe to open model.

www.researchprofessionalnews.com/rr-news-uk-o...

16.02.2026 09:47 β€” πŸ‘ 9    πŸ” 7    πŸ’¬ 0    πŸ“Œ 1
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Display an album that was important to you when you were nineteen

15.02.2026 17:20 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
A Crisp Morning. 1Β°C and snow just South of Edinburgh. Rooks

A Crisp Morning. 1Β°C and snow just South of Edinburgh. Rooks

A Crisp Morning. 1Β°C and snow just South of Edinburgh. Rooks.

15.02.2026 12:04 β€” πŸ‘ 92    πŸ” 11    πŸ’¬ 2    πŸ“Œ 1
Snowdrops and crocuses appear through light snow on rocky ground

Snowdrops and crocuses appear through light snow on rocky ground

β€œSnow has fallen again, as it will sometimes do in February”

What to Look for in Winter, 1959
Artist: CF Tunnicliffe
Writer: EL Grant Watson

15.02.2026 08:48 β€” πŸ‘ 359    πŸ” 65    πŸ’¬ 5    πŸ“Œ 3
Photo-realistic close-up of a hard boiled egg sitting in a blue and white ceramic egg cup.
The top of the egg has been roughly taken off, ready to eat

Photo-realistic close-up of a hard boiled egg sitting in a blue and white ceramic egg cup. The top of the egg has been roughly taken off, ready to eat

Beautiful everyday Ladybird things.
Boiled eggs and Cornishware (2nd Picture Book, 1970)

Artist: Harry Wingfield

12.02.2026 20:35 β€” πŸ‘ 580    πŸ” 81    πŸ’¬ 9    πŸ“Œ 2
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Our Best Models Working Group can offer advice on the use of a range of model systems.

The next in our series of #MeetTheExpert posts features Owen Sansom, whose group has created advanced mouse models matching a variety of human colorectal cancer subtypes.

nmgn.mrc.ukri.org/working-grou...

12.02.2026 12:51 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Do you work or study in the fields of psychology, neuroscience, computer science, artificial intelligence, or philosophy?

What does the term 'representation' mean to you?

We invite you to participate in a brief survey on key conceptual questions across fields.

eu.surveymonkey.com/r/VX9GNXM

12.02.2026 13:39 β€” πŸ‘ 35    πŸ” 36    πŸ’¬ 2    πŸ“Œ 2
The love of all living creatures is the most noble attribute of man. Charles Darwin. Naturalist and humanist.

The love of all living creatures is the most noble attribute of man. Charles Darwin. Naturalist and humanist.

Happy Darwin Day everyone! #Onthisday 217 years ago, Charles Darwin was born. We mark Darwin Day on 12 February every year, with millions of people across he globe, celebrating the life and legacy of Charles Darwin – humanist, philanthropist, and the most influential biologist in history.

12.02.2026 10:00 β€” πŸ‘ 54    πŸ” 16    πŸ’¬ 2    πŸ“Œ 3
I hate myself, I hate clover and I hate bees. Charles Darwin - Letter to John Lubbock. 3 Sep 1862

I hate myself, I hate clover and I hate bees. Charles Darwin - Letter to John Lubbock. 3 Sep 1862

While #DarwinDay is certainly a day to celebrate #CharlesDarwin and how he fundamentally changed humanity's understanding of all life on Earth...

It’s also the perfect excuse to share this letter he wrote while being magnificently grumpy about bees 🧡

12.02.2026 11:02 β€” πŸ‘ 48    πŸ” 10    πŸ’¬ 3    πŸ“Œ 1
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Our Best Models Working Group can offer advice on the use of a range of model systems.

The next in our series of #MeetTheExpert posts features Laura Greaves, whose group investigates the role of age-related mitochondrial DNA mutations in cancer biology

nmgn.mrc.ukri.org/working-grou...

10.02.2026 08:37 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
A Glimpse Of The Sun. 7Β°C and a gentle Southeasterly. Rabbits.

A Glimpse Of The Sun. 7Β°C and a gentle Southeasterly. Rabbits.

A Glimpse Of The Sun. 7Β°C and a gentle Southeasterly.
Rabbits.

07.02.2026 10:45 β€” πŸ‘ 203    πŸ” 35    πŸ’¬ 3    πŸ“Œ 4

Well done Emma! πŸ‘πŸ‘

11.02.2026 10:05 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Plans to invade Greenland have just been cancelled after this

09.02.2026 06:41 β€” πŸ‘ 6631    πŸ” 2092    πŸ’¬ 154    πŸ“Œ 530

Three episodes into this series and I can say it provides a fascinating insight into the scientific process, #DrugDiscovery and development, #BigPharma and the biology of obesity… oh, and @gilesyeo.bsky.social’s dietary habits

10.02.2026 11:22 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
A close-up illustration looking down on a falcon in flight over mountains in a cloudy blue sky

A close-up illustration looking down on a falcon in flight over mountains in a cloudy blue sky

β€˜Peregrine’
Birds of Prey, 1970
Artist: John Leigh-Pemberton

09.02.2026 08:11 β€” πŸ‘ 274    πŸ” 38    πŸ’¬ 0    πŸ“Œ 1
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The new leader of Reform UK Wales lives in Bath, not Wales Martin Shipton The newly appointed leader of Reform UK in Wales hasn’t moved back to his home town in the Valleys, but has bought a Β£1m house near Bath, we can reveal. Dan Thomas, the former Conservat...

Have a read of this. Great scoop, obviously, but it’s also an absolute masterclass in how to report on these jokers. Plenty of London-based hacks could learn a lot from Martin Shipton here. If they actually wanted to…
nation.cymru/news/the-new...

07.02.2026 11:38 β€” πŸ‘ 1518    πŸ” 681    πŸ’¬ 98    πŸ“Œ 39
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Happy #Lawyercat Anniversary for all who celebrate! It's been four years since the kitten appeared in my Zoom courtroom, and I released the 48 second video that made the whole world laugh. Here is the full video showing the big reveal at the end (in two parts because Blue sky). Enjoy!

09.02.2025 15:08 β€” πŸ‘ 3298    πŸ” 872    πŸ’¬ 92    πŸ“Œ 138

Happy Monday!

09.02.2026 14:21 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Still can't get over how magnificent this 15th century medieval hammer-beam roof is at St Colleen's in Llangollen. It's glorious!!! #Wales #Church #medieval #History

08.02.2026 17:50 β€” πŸ‘ 242    πŸ” 47    πŸ’¬ 0    πŸ“Œ 1
Flooded fields under a leaden sky, a scene that could be the Somerset Levels

Flooded fields under a leaden sky, a scene that could be the Somerset Levels

β€œHeavy rains that often fall in February have flooded the low-lying meadows in the broad valley.”
β€˜What to Look for in Winter’, 1959
Artist: CF Tunnicliffe
Writer: EL Grant Watson

08.02.2026 08:18 β€” πŸ‘ 427    πŸ” 79    πŸ’¬ 5    πŸ“Œ 4
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Interested in antisense oligonucleotides?
Check our story about downstream-of-gene ASOs (DG-ASOs)!
Together with the Roche Innovation Center we
identified transcription termination windows of protein-coding genes as ASO target regions.

link to BioRxiv:
www.biorxiv.org/content/10.6...

08.02.2026 11:03 β€” πŸ‘ 18    πŸ” 9    πŸ’¬ 1    πŸ“Œ 1
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How US fried chicken craze is transforming British takeaways An internet craze for American-style chicken has come to the UK, but what does it mean for traditional chippies?

Never been to a fried chicken shop in my life (apart from KFC when I was 8…), and probably never will

www.bbc.co.uk/news/article...

08.02.2026 10:11 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
A scenic view of King's College, Cambridge, featuring a prominent tree and a carpet of bright yellow flowers in the foreground. The college building and chapel are visible in the background, framed by the clear blue sky and additional trees.

A scenic view of King's College, Cambridge, featuring a prominent tree and a carpet of bright yellow flowers in the foreground. The college building and chapel are visible in the background, framed by the clear blue sky and additional trees.

Spring arriving quietly at the Backs, with @kingscollege.bsky.social keeping watch 🌼

πŸ“Έ Lloyd Mann

#CambridgeUniversity #KingsCollegeCambridge #Cambridge #UniversityOfCambridge

07.02.2026 17:12 β€” πŸ‘ 12    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

Really shocked to hear of the death of Annette. She was #BNA President during my time as a trustee and was very supportive of everyone's efforts at the #BNA, and of #neuroscience and #neuroscientists in the UK in general.
I also liked to talk to her about #Cricket 🏏
She will be greatly missed.

07.02.2026 12:55 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

So now we have it- not only the reduction from 12-13 to 3 grants from each board recommended for funding but the budget for applicant-led research to be reduced from Β£200 million to Β£113 million per year. This is appalling, Especially given all that is happening with medical research in the US.

06.02.2026 10:04 β€” πŸ‘ 19    πŸ” 13    πŸ’¬ 2    πŸ“Œ 1
A stark, bare landscape of flat ground, ploughed field and stream under a grey sky is enlivened by detailed studies in the foreground of the plants and flowers of February

A stark, bare landscape of flat ground, ploughed field and stream under a grey sky is enlivened by detailed studies in the foreground of the plants and flowers of February

β€œFebruary. Another cold, dead month, or so it seems. The elms are bare against the sky, the plough-ground is naked and wet, and still as brown as the sodden leaves.
Yet the world is waking up”.

Artists: Edith Hilder, Rowland Hilder (ShellGuide, 1955)

07.02.2026 08:03 β€” πŸ‘ 394    πŸ” 64    πŸ’¬ 5    πŸ“Œ 3
A very loose, spare, painterly watercolour of a long view over a flat expansive landscape dotted with winter trees in broken sunshine under a cloudy sky

A very loose, spare, painterly watercolour of a long view over a flat expansive landscape dotted with winter trees in broken sunshine under a cloudy sky

Other work of the Ladybird artists.
A February Day
Artist: Rowland Hilder

05.02.2026 20:28 β€” πŸ‘ 440    πŸ” 76    πŸ’¬ 7    πŸ“Œ 2

Marvellous. It can summarise all the AI-written crap that we are being flooded with, and then we will have a perfect spiral of ever-growing mediocrity. THE POINT OF READING IS TO UNDERSTAND, CRITICALLY, not tick a box grumble grumble.

06.02.2026 14:36 β€” πŸ‘ 11    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
An oak tree with the sun behind it

An oak tree with the sun behind it

Beauty is in the eye of the treeholder

04.02.2026 14:42 β€” πŸ‘ 319    πŸ” 58    πŸ’¬ 0    πŸ“Œ 1

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