Jakke Neiro

Jutussa arvoidaan, että ero johtuisi erosta tutkintojen pituudessa (Suomi 3v vs USA 4v).

Joku hullunrohkea voisi sanoa, että se johtuu siitä, että USA opettaa paremmin kuin koulutuksen mallimaa Suomi.

Ylen jutusta "Suomalaisilla opiskelijoilla on korkeakouluopintojen alussa keskimäärin paremmat kriittisen ajattelun taidot kuin yhdysvaltalaisten verrokkiyliopistojen opiskelijoilla. Alemman korkeakoulututkinnon loppuvaiheessa merkittävää osaamiseroa ei enää ole."

The Spiralian Organiser
(enriched with dpERK1/2)
🪱🎃🪱🎃🪱

#DevBio
#EvoDevo
#SciArt

*almost* all

What is the unit of morphological evolution, and how many of these units amount to almost all?

Can't believe it — my first‑author paper is out and my image graces the cover of @dev-journal.bsky.social 🎉

Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life
🔗 journals.biologists.com/dev/issue/15...

#FluorescenceFriday #LifelongDevSI

Exploring the potential of Schmidtea mediterranea as a model for reproductive toxicity through analysis of sterility caused defective m6A RNA regulation Development of alternative methods for analysis of reproductive toxicity is a challenge that requires the characterization of mechanistic endpoints li…

Exploring the potential of Schmidtea mediterranea as a model for reproductive toxicity through analysis of sterility caused defective m6A RNA regulation - ScienceDirect
www.sciencedirect.com/science/arti...

Just going to leave this rather frightening reference about the change in global mammalian biomass from 1860 to now here. 😳🧪

www.nature.com/articles/s41...

Been there, done that.

Probably sunshine

I love AlphaFold—but please include PAE (Predicted Aligned Error) plots for every “interaction.” Pretty PDBs ≠ proof. If the PAE doesn’t show an interface, it ain’t one. Show the plots. Structural biology's reputation is on the line.

Harvard FAS Cuts Ph.D. Seats By More Than Half Across Next Two Admissions Cycles | News | The Harvard Crimson The Faculty of Arts and Sciences slashed the number of Ph.D. student admissions slots for the Science division by more than 75 percent and for the Arts & Humanities division by about 60 percent for…

The Faculty of Arts and Sciences slashed the number of Ph.D. student admissions slots for the Science division by more than 75 percent and for the Arts & Humanities division by about 60 percent for the next two years.

William C. Mao and Veronica H. Paulus report.

www.thecrimson.com/article/2025...

Nobel Prize in Physiology or Medicine 2012 The Nobel Prize in Physiology or Medicine 2012 was awarded jointly to Sir John B. Gurdon and Shinya Yamanaka "for the discovery that mature cells can be reprogrammed to become pluripotent"

Honouring the life of Sir John Gurdon, who died earlier this week: awarded the Nobel Laureate in Physiology or Medicine for seminal work carried out in Oxford Zoology (now @biology.ox.ac.uk) showing that mature cells could be reprogrammed to become pluripotent.

www.nobelprize.org/prizes/medic...

John Gurdonin muistoa kunnioittaen - kävi myös Suomessa aikoinaan saamassa Yrjö Reenpään mitalin vuonna 1979.

Reporter CRISPR screens decipher cis-regulatory and trans-regulatory principles at the Xist locus - Nature Structural & Molecular Biology Here Schwämmle et al. develop CRISPR reporter screens to map transcription-factor-regulatory element interactions at the Xist locus, revealing a two-step mechanism integrating developmental and X-dosage signals to initiate X-chromosome inactivation.

⚠️ Paper alert: Using a novel CRISPR screening approach, we mapped the entire regulatory network controlling Xist—key for X-chromosome inactivation.
👉 We discover how sex and development signals are decoded at a single gene locus.
www.nature.com/articles/s41...
👇 Bluetorial

Dissecting the impact of transcription factor dose on cell reprogramming heterogeneity using scTF-seq - Nature Genetics This study introduces single-cell transcription factor (TF) sequencing, a single-cell barcoded and doxycycline-inducible TF overexpression approach that reveals dose-sensitive functional classes of TFs and cellular heterogeneity by mapping TF dose-dependent transcriptomic changes during the reprogramming of mouse embryonic multipotent stromal cells.

🧵1/ Excited to share our new paper introducing a new #singlecell assay: scTF-seq, a high-throughput single-cell approach to explore how transcription factor (TF) dose shapes cell identity and reprogramming outcomes. 🔗 www.nature.com/articles/s41... Big congrats to the entire team @EPFL & @SIAT_China

Bioelectricity in Morphogenesis Bioelectricity is likely as old as life itself. From the moment the first proto-cell was enclosed in a lipid bilayer, a membrane potential arose. Thus, one can expect that bioelectrical activities inf...

New Review! #devbiol #bioelectricity #CellBiology #tissueregeneration

In our new @annualreviews.bsky.social piece, we explore how bioelectricity is generated, sensed & translated into responses that sculpt tissues, guide growth & enable tissue regeneration.

www.annualreviews.org/content/jour...

Rachel Carson’s Silent Spring was published OTD in 1962.

“[W]e have now acquired a fateful power to alter and destroy nature. But man is a part of nature, and his war against nature is inevitably a war against himself.”

🌱🐋 # HistSTM 🧪🌎 #philsci #philsky #WomeninSTEM

The salamander takes it all
The loser's standing small
Beside the victory
That's her destiny

Tvärminne.

The forsaken place where I have spent almost a fortnight dissecting amphipods and their eyes in darkness.

Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life.
www.nature.com/articles/s41...

Fab thread about one of the (many) things one walks past in Oxford without much thought...

The Iberian ribbed newt has the ability to heal its own heart after an injury. The secret might lie in a specific protein also found in humans. Elif Eroglu @ki.se studies salamanders to discover new ways of regenerating our heart cells after a #heartattack.
#research #medicine tinyurl.com/mssmcmc2

Do apply, especially for the position in Molecular Cell Biology!

Figure showing sagittal sections of a cephalochordate and a hemichordate highlighting potentially homologous structures

My review of the evidence (morphological, embryological and molecular) for the deuterostomes clade is now available. www.annualreviews.org/content/jour...

Slay

Sad to hear that David Baltimore died. I am one of hundreds of scientists that David generously mentored, supported, and inspired. His influence on each of us was deep and lasting, and his impact on the world immeasurable. Arguably David Baltimore is one of the greatest scientists of any generation.

If you want to feel like you know nothing about biology, read this paper. 😭 I want to get it. But brain not cooperating.

SoxB1-Mediated Chromatin Remodeling Promotes Sensory Neuron Differentiation in Planarians Understanding how adult stem cells generate neurons is critical for advancing regenerative medicine. However, few in vivo models enable studying how stem cell fates are specified as neurons in an adul...

SoxB1-Mediated Chromatin Remodeling Promotes Sensory Neuron Differentiation in Planarians | bioRxiv
www.biorxiv.org/content/10.1...

Peripheral muscle fibers (pseudocolored in magenta) and nuclei (in gray)

Today's #FluorescenceFriday is featuring the peripheral muscle of Hofstenia miamia 💪