Beppe Battaglia

#LRP1‑targeted #polymersomes reprogram #BloodBrainBarrier trafficking, enabling rapid #Amyloidβ clearance and sustained cognitive recovery in #AlzheimersDisease models. @beppebattaglia.bsky.social @ucl.ac.uk @icta-uab.bsky.social

#CoverPage in #STTT: doi.org/10.1038/s413...

A multivalent angiopep-2 polymersome that targets LRP1 in the BBB modulates receptor-mediated transport and biases LRP1 trafficking toward #Transcytosis to promote efficient Aβ removal. @beppebattaglia.bsky.social @ucl.ac.uk @icta-uab.bsky.social

#OpenAccess: doi.org/10.1038/s413...

#PCBCommunity |🧠 Científics de @ibecbarcelona.eu aconsegueixen revertir l’ #Alzheimer en ratolins amb només tres injeccions de #nanopartícules per a restaurar la funció normal del sistema vascular en lloc d’actuar sobre les neurones o cèl·lules cerebrals, com s’ha fet fins ara. 💉🐁

👉 tuit.cat/iDeul

The minimal chemotactic cell Encapsulated enzymes and transmembrane proteins are the minimal elements required to endow vesicles with chemotaxis.

The minimal chemotactic cell
Science Advances
www.science.org/doi/10.1126/...

💡A RES Success Story to advance Neurodegenerative Disease Research💡

📋"LRP1's extended glycosylation may affect the protein's quaternary structure formation and stability" led by @beppebattaglia.bsky.social from @IBECBarcelona

🖥️ #Cibeles @uam.es

👉Full story: www.linkedin.com/feed/update/...

#acsnano | Giuseppe Battaglia Our latest work, published in #ACSNano and showcased in the issue cover, shows how to grow 2 nm gold nanoparticles inside polymersome membranes — not as decoration, but as engines. These tiny plasmoni...

Very happy to share our latest #ACSNano work!
www.linkedin.com/feed/update/...

Morphological insights in oxidative sensitive nanocarrier pharmacokinetics, targeting, and photodynamic therapy Nanoparticle (NP) morphology holds significant importance in nanomedicine, particularly concerning its implications for biological responses. This study investigates the impact of synthesizing polymer...

Out in
@jmaterchem.rsc.org B. We’re excited to share our research on nanoparticle morphology! Check out our findings here: [Link](pubs.rsc.org/en/content/a...) #Nanomedicine #DrugDelivery

🚨 PhD Opportunities at IBEC! 🚨

Join #IBEC, a Severo Ochoa Research Centre, and start your research career with one of 12 fully-funded PhD fellowships in bioengineering! 🌟

Matter still remains,
reshuffled like a deck—yet
life’s flush is now gone.

🆕 We’re now on BlueSky! 🌐✨

Follow us for the latest updates in #bioengineering, groundbreaking #research, and inspiring initiatives from #IBEC. 🎓🔬

We’ll share engaging content in English, Catalan, and Spanish.

Stay tuned and let’s explore together! 🚀

A Cixin Liu inspired haiku. -Vast universe swells,
light too frail to span its reach—
limbs lost to the void.

a man in a blue shirt is walking down a dirt road surrounded by trees ALT: a man in a blue shirt is walking down a dirt road surrounded by trees

Sometime only for the length of the trip+talk

But then I remember Prigogine and I paraphrase him. Molecules and atoms are inmortal only when they come together they age.

How did the universe start? A question without answer. But how about a different question, what’s time? And now if we have time we have a start if we don’t we don’t. Again no answer.

for his discovery of the therapeutic value of leucotomy in certain psychoses”

🎥 Watch Dr. Carla Garcia-Cabau, the first author of the study, along with Dr. Anna Bartomeu, explain the details of this research work.

▶️ youtu.be/KPrxBSPQ03o

#IRBScience

🗣️Dr. @xsalvatella1.bsky.social: "In this study, we’ve discovered that this neuronal microexon is crucial for maintaining the condensates' stability & dynamics formed by #CPEB4 in neurons. Without it, condensates are less dynamic and can form solid aggregates that don’t work correctly."

🫧🔍Key breakthrough in #autism: pivotal role of #CPEB4 condensates revealed.

💊The study opens new avenues for the development of targeted treatments for autism.

📰 Nature @natureportfolio.bsky.social

✍️ Carla Garcia-Cabau, Anna Bartomeu et al.

➡️ bit.ly/3BfEGlR

📌 DOI: 10.1038/s41586-024-08289-w