Luis-Carlos Tábara

Molecular mechanisms of mitochondrial dynamics - Nature Reviews Molecular Cell Biology Mitochondrial fusion and fission events are tightly regulated by core mitochondrial dynamics proteins. Recent structural and functional findings have characterized how these proteins interact with eac...

Please have a look at our recent review on the molecular mechanisms of mitochondrial dynamics go.nature.com/405NTaf

MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels MTFP1 prevents altered inner mitochondrial membrane subdomains from fusing with the healthier mitochondrial network, enabling their isolation and subsequent autophagic degradation. The findings provid...

10/2024. Thrilled to announce that our project has been published in @CellCellPress. In this work, we link mitochondrial dynamics to mitochondrial quality control and mtDNA maintenance by characterizing the molecular function of MTFP1.

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