CRISPR as a microbial immune system
In 2003, Mojica wrote the first paper suggesting that CRISPR was an innate microbial immune system. The paper was rejected by a series of high-profile journals, including Nature, Proceedings of the National Academy of Sciences, Molecular Microbiology and Nucleic Acids Research, before finally being accepted by Journal of Molecular Evolution in February, 2005.[3][4]
TIL the original paper describing CRISPR, by Francisco Mojica, was rejected by 4 journals and took 2 years to be published
17.08.2025 04:00 β π 297 π 76 π¬ 6 π 9
With Tom Lehrer's passing, I suppose this is a moment to share the story of the prank he played on the National Security Agency, and how it went undiscovered for nearly 60 years.
27.07.2025 21:01 β π 8611 π 3631 π¬ 146 π 715
My new paper has been accepted at Synthese!
I tackle an ongoing problem with the learning of compositional communication in conventional signaing games.
I build two new models to show that structured receivers can learn and retain compositional information.
philpapers.org/rec/FRECUI-2
21.07.2025 16:07 β π 1 π 1 π¬ 0 π 0
The distribution of the Red-billed chough is absolutely bizarre.
09.07.2025 12:16 β π 0 π 0 π¬ 0 π 0
Sometimes I look at my bibliographies and think... I bet these papers have never been cited together before.
04.07.2025 05:06 β π 1 π 0 π¬ 0 π 0
STAGGERING: This new study of 133 countries is the first to estimate the impact of all USAIDβs work. In 2 decades, it has saved *92M* lives. Current cuts, if not reversed, are forecast to cost up to *14M* lives thru 2030. www.thelancet.com/journals/lan...
01.07.2025 14:23 β π 3743 π 2390 π¬ 96 π 808
In our latest paper, we discovered a surprising result: training LLMs with self-play reinforcement learning on zero-sum games (like poker) significantly improves performance on math and reasoning benchmarks, zero-shot. Whaaat? How does this work?
01.07.2025 20:23 β π 59 π 7 π¬ 2 π 2
YouTube video by Emancipations with Daniel Tutt
A Social History of Analytic Philosophy (feat. Christoph Schuringa)
Check out this fascinating and detailed interview with NU London's Christoph Schuringa @schuringa.bsky.social, speaking about his new book A Social History of Analytic Philosophy!
www.youtube.com/watch?v=y_iu...
26.06.2025 18:02 β π 5 π 3 π¬ 1 π 0
Excited to be at Ford's innovation space in the Stratford Olympic Park, for a Conversations On AI event on how we can use AI to innovate for human benefit. The panel features NU London Philosophy's own Hossein Dabbagh, and the event series is organised by alumni from our MA Philosophy and AI
25.06.2025 16:23 β π 1 π 1 π¬ 0 π 0
The games business is about games. If youβre in the games business, and somehow (as often happens) your company somehow is now focused on something else (AI, XR, βIP,β acquisitions, etc.) youβre in for a period of struggle. Everyone will wonder whatβs wrong. But you know. Itβs about games. Gameplay.
25.06.2025 15:05 β π 712 π 169 π¬ 11 π 16
Headline of an article with a picture of some cells, it reads "Scientists have discovered `third state' between life and death"
There's no way scientists are only just now learning about grad school
17.06.2025 07:42 β π 372 π 69 π¬ 6 π 4
I decided to become a journalist aged fifteen after reading β1984β and being appalled at the thought that governments could rewrite history. Orwell knew the USSR did it. Now China pretends the Tiananmen massacre didnβt happen. It did. I was there, and saw it for myself.
03.06.2025 16:09 β π 2361 π 522 π¬ 91 π 12
Delighted to be at the launch of the The Computational Philosophy Lab at Northeastern University London. Brian Ball is giving the welcome talk. Later we will hear from @alicehelliwell.bsky.social @dpwf0.bsky.social, @tessbuckley.bsky.social amongst others. Learn more here: cpl.sites.northeastern.edu
30.05.2025 09:47 β π 2 π 1 π¬ 0 π 0
The Computational Philosophy Lab launch
Join us for the launch of the Computational Philosophy Lab
Huge News: The Computational Philosophy Lab (CPL) is launching tomorrow at 10:00!
The CPL will be the UK's first and premier centre dedicated to computationally-enabled & AI-enhanced philosophy.
Location: Devon House 58 Saint Katharine's Way, London, E1W 1LP
www.eventbrite.co.uk/e/the-comput...
29.05.2025 20:22 β π 1 π 1 π¬ 0 π 0
24.05.2025 08:54 β π 1883 π 330 π¬ 25 π 23
I think there are plenty of annoyances that might also drive away right wingers. E.g. the top 50 replies to any post being braindead bluetick slop. The insane 'for you' feed. Insofar as you can decouple the contemporary political right from this rubbish, it must still be grating to many.
24.05.2025 10:25 β π 3 π 0 π¬ 1 π 0
It would be hard to overstate the ongoing costs of the public sector's use of Big IT vendors. Stunning that it's still ongoing, 15 years after GDS started the fight to escape. I'm thinking, e.g. major systems provided by CGI, Accenture, et al, that are 20+ years behind today's digital services. 1/n
23.05.2025 09:53 β π 28 π 9 π¬ 4 π 2
This is a view from the surface of Comet 67P.
The busy particles in the foreground are cosmic rays or bits of dust and ice.
The dots moving in the background are stars.
23.05.2025 17:27 β π 11939 π 2205 π¬ 327 π 229
Well worth reading to get a sense of the scale of the cuts to public science funding in the US. It might take decades to recover from this damage.
www.nytimes.com/interactive/...
22.05.2025 21:23 β π 0 π 0 π¬ 0 π 0
Moderna withdraws application for COVID-flu combination vaccine
Moderna said on Wednesday it has withdrawn an application seeking approval for its flu and COVID combination vaccine candidate after discussions with the U.S. Food and Drug Administration.
This is absolutely terrible news.
With the shifting regulatory climate (i.e., antivax ratfuckery), Moderna has withdrawn their application for their eagerly anticipated COVID-flu combo vaccine. This vaccine offered better protection than getting each shot separately.
h/t @merz.bsky.social
22.05.2025 06:46 β π 12620 π 5931 π¬ 397 π 650
Clearly I have more influence than I thought! xAI claim they will now publish Grok's system prompts openly on GitHub.
16.05.2025 12:44 β π 0 π 0 π¬ 0 π 0
The Computational Philosophy Lab launch
Join us for the launch of the Computational Philosophy Lab
Join us for the launch of the Computational Philosophy Lab, the UK's first and premier centre dedicated to computationally-enabled and AI-enhanced philosophy.
Date: May 30 β’ 10:00 am
Location: Devon House 58 Saint Katharine's Way, London, E1W 1LP
www.eventbrite.co.uk/e/the-comput...
15.05.2025 08:27 β π 2 π 2 π¬ 0 π 0
If you wish to train a large language model from scratch, you must first invent the universe.
12.05.2025 08:04 β π 2 π 1 π¬ 0 π 0
Theyβre here π
@versobooks.bsky.social
08.05.2025 08:40 β π 135 π 24 π¬ 10 π 6
Wow. It must be nice to be able to get paid to write error-filled polemics in turgid prose on topics you're almost entirely ignorant about. I don't think there's a claim in this that isn't false. Endlessly tossing-off lazy culture war screeds is a cushy way to make a living.
05.05.2025 09:59 β π 21 π 4 π¬ 2 π 0
Very close to the some arguments put forward in "Explaining Postmodernism" by Stephen Hicks and "The Once and Future Liberal" by Mark Lilla! I'm sure you'll enjoy these comparisons...
05.05.2025 09:39 β π 1 π 0 π¬ 1 π 0
Professor of Comparative Democratic Institutions, Nuffield & University of Oxford, FBA. http://benansell.substack.com. Why Politics Fails. BBC Reith Lecturer 2023. Host of Whatβs Wrong With Democracy? and BBC Radio 4βs Rethink
Incoherent superposition of education, writing, editing, consulting, outreach, and partnerships. Resonances include #author #teacher #LEGO #Physics #books www.youtube.com/drbenstill
Work in environmental policy. Currently lurking.
Check out my podcast >>> @ministryoffilmpod
PhD supervised by Tim RocktΓ€schel and Ed Grefenstette, part time at Cohere. Language and LLMs. Spent time at FAIR, Google, and NYU (with Brenden Lake). She/her.
Surgeon, Writer ("Being Mortal," "Checklist Manifesto"), and formerly led Global Health @USAID.
Reinforcement Learning PhD @NUSingapore | Undergrad @PKU1898 | Building autonomous decision making systems | Ex intern @MSFTResearch @deepseek_ai | DeepSeek-V2, DeepSeek-VL, DeepSeek-Prover
Assemblymember. Democratic Nominee for Mayor of NYC. Running to freeze the rent, make buses fast + free, and deliver universal childcare. Democratic Socialist. zohranfornyc.com
PhD student at Paris School of Economics.
International Political Economy, Geoeconomics, Globalization and Inequality.
National Accounts coordinator WIL
gastonnievas.com
Professor at EHESS & PSE
Co-Director, World Inequality Lab
inequalitylab.world | WID.world
http://piketty.pse.ens.fr/
Illuminating the debate through data-driven research #inequalitydataβ¨
Hosting the World Inequality Databaseπ https://wid.world/
https://inequalitylab.world/en/
hi this is @annierau.bsky.social! my DMs are open
Taiwan's defense, military history, and U.S.-Taiwan relations. π the China Coast Guard at PLATracker. Georgetown University Security Studies Program. Go Tigers!
δΈζ/ENG/FR
Chief of Space Policy at The Planetary Society. Host of Planetary Radio: Space Policy Edition. planetary.org
Assistant Professor @VUamsterdam, Philosophy of Psychology, Language, Technology, AI, π€, Social Ontology, Conceptual Engineering, he/they
Interested in more human ways to govern our lives together, and how technology can help. Blog: https://medium.com/@jamestplunkett π³οΈββ§οΈ
Associate Professor of Earth, Environmental, and Planetary Science at Washington University in St. Louis β’ Planetary Data System Geosciences Node Director β’ Planetary Bastard β’ he/him/Sir
Part-time writer. Political activist. Fan of Bradford City and rail travel (amongst other things). Bibliophile. Dad. List not necessarily in order of importance.
Economics writer. Author.
Expect history, economics, finance and other stuff.
Wrote Two Hundred Years of Muddling Through.
Blood and Treasure, on the economics of war, out now.
Philosophy/Consciousness/History/Books
Editor, Institute of Art & Ideas β @iai.tv
Freelance for Hurst Pub β @hurstpublishers.bsky.social
Instructor, Philosophy of Mind β Horizoninspires.com
DPhil, Philosophy, University of Oxford
πEdinburgh, Scotland
An independent group of scientists providing transparent advice during the COVID crisis.