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ThePatrick&WatsonLabs

@thepwlab.bsky.social

Our labs study innate immune regulation during bacterial infection. We focus on interplay between mitochondria and Mycobacterium tuberculosis (Robbie Watson) and post-transcriptional control of macrophage activation (Kristin Patrick). Views are our own.

1,604 Followers  |  326 Following  |  80 Posts  |  Joined: 21.09.2023  |  2.0557

Latest posts by thepwlab.bsky.social on Bluesky

Any plant biologist with a funded NIH R35 MIRA ESI willing to share their proposal with me? THANKS. #PlantSciences

07.08.2025 01:38 β€” πŸ‘ 13    πŸ” 16    πŸ’¬ 2    πŸ“Œ 0
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a bald man in a blue suit is making a face . ALT: a bald man in a blue suit is making a face .

Preprint on tandem split-GFP influenza viruses is now up! We strung 7 copies of GFP11 together to make a bright virus with minimal fitness defects. Fluorescence requires GFP1-10 from cells, so we made a few that are relevant for flu. See this fluorescent love story: www.biorxiv.org/cgi/content/...

28.07.2025 15:47 β€” πŸ‘ 29    πŸ” 11    πŸ’¬ 0    πŸ“Œ 0

www.saranac.com

17.07.2025 01:37 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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a woman with a surprised look on her face and the words `` pretends to be shocked '' written below her . ALT: a woman with a surprised look on her face and the words `` pretends to be shocked '' written below her .

A P/W lab student who had his F31-DIV terminated just got a very fundable score on the (same) F31 he submitted again as a new application in April.

Its almost as if his science and aptitude had nothing to do with "DEI" πŸ€”

Hope this inspires others with unfairly terminated awards to try again!

15.07.2025 17:16 β€” πŸ‘ 7    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

Scientist boy band?

12.07.2025 23:26 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Yay!!! But also explain this to meβ€”GA wasn’t part of the lawsuit, right? Everyone keeps saying it’s restricted to states that sued, but NIH actions are maybe inconsistent with that (I hope?)

02.07.2025 21:14 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Plans within plans: post-transcriptional regulation governs macrophage responses Macrophages are sentinels and first responders of the innate immune system. By sensing danger signals, they initiate and amplify inflammatory and rege…

Want to learn more about all the ways macrophages regulate their functions downstream of transcription? Check out our new review, the brainchild of two talented trainees: Mackenzie Smith @u2afwho.bsky.social in the Patrick lab and Ed Courvan in the Parker lab.

www.sciencedirect.com/science/arti...

30.06.2025 21:51 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

The Post Malone ones are also quite good.

29.06.2025 16:54 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

IAI: Zero open access fees and a reasonable review process.
5 stars, will be back!

⭐️ ⭐️ ⭐️ ⭐️ ⭐️

26.06.2025 23:54 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

But if they’re blocking all pending terminations… πŸ€”

25.06.2025 16:52 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Does anyone know if terminated grants from states not in the lawsuit have a chance of being reinstated? Two F31-DIVs terminated in red states over here…

25.06.2025 16:21 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Microbial Pathogenesis & Host Response Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.

Alert! The abstract deadline for the Microbial Pathogenesis & Host Response meeting has been extended to July 7 meetings.cshl.edu/meetings.asp...

23.06.2025 20:24 β€” πŸ‘ 37    πŸ” 23    πŸ’¬ 1    πŸ“Œ 2

Congrats Helene! Cool story!

23.06.2025 06:38 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Delicious with a cold glass of cholera-laden raw milk.

17.06.2025 20:24 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Are you looking for a faculty job? We are hiring in my department at Roswell Park NOW. Contact me for details as I await the formal ad. (Please RT.)

04.06.2025 18:34 β€” πŸ‘ 71    πŸ” 100    πŸ’¬ 2    πŸ“Œ 4
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Beautiful science in a beautiful place with beautiful people. Having a great time at #RNA2025

30.05.2025 23:18 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Got it. Thanks!

19.05.2025 21:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Amazing news! Quick question (since we need to crowd source our understanding of the NIH these days), was yours a new MIRA or a non competing renewal of an already awarded one? I’m trying to figure out what happening with MIRAs that were already awarded but have a PEDP...

19.05.2025 19:29 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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β€œLook, it’s a macrophage.”

17.05.2025 15:46 β€” πŸ‘ 9    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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1/3 It’s official πŸ™ŒπŸ½
The Reyes Ruiz Lab is opening in 2026 at the University of Wisconsin, Madison in the Department of Pathobiological Sciences. My lab will focus on host antibacterial effectors and adaptation of bacteria to host-imposed stress during S. aureus infections.

14.05.2025 03:40 β€” πŸ‘ 129    πŸ” 19    πŸ’¬ 30    πŸ“Œ 3

Best news of the day! Congratulations!

14.05.2025 12:59 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Our lab love language is sharing food, so we had to have breakfast AND lunch in honor of Robbie on his birthday!

12.05.2025 19:55 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0
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Celebrating a successful RNA in Immunity session with all our favorite scientists, sponsored by the @cytokinesociety.bsky.social at #immunology2025. @carpenterlab.bsky.social @ramlabuw.bsky.social @naehasubramanian.bsky.social @heleneliu.bsky.social

06.05.2025 02:51 β€” πŸ‘ 19    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0
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It was a huge pleasure to represent @cytokinesociety.bsky.social at AAI to discuss RNA and immunity. Thanks to my co-chair @ramlabuw.bsky.social and all our fabulous speakers @thepwlab.bsky.social @naehasubramanian.bsky.social and @heleneliu.bsky.social. Mahalo!

05.05.2025 22:13 β€” πŸ‘ 11    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

CELF2 suppresses immunostimulatory endogenous RNAs that activate the RIG-I-MAVS pathway in macrophages, preventing type I IFN-signature. Congrats to Julian Smith, Olivia Kern, and all the co-authors for their hard work! #innateimmunity #dsRNA #IFN

www.biorxiv.org/content/10.1...

01.04.2025 22:28 β€” πŸ‘ 16    πŸ” 8    πŸ’¬ 0    πŸ“Œ 1
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Fantastic session on tissue immunity this afternoon by these four amazing women scientists! #aai2025 #immunology2025

04.05.2025 23:05 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Excited to be reminded of all the reasons it’s an amazing privilege to be a scientist. Ready for #immunology2025.

03.05.2025 03:50 β€” πŸ‘ 11    πŸ” 1    πŸ’¬ 2    πŸ“Œ 0

Yesssssss! Well deserved! I hope it gives you a break from grant writing for a minute :)

30.04.2025 02:37 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Can we get a show of hands of labs studying these exact f*cking things?

23.04.2025 16:37 β€” πŸ‘ 33    πŸ” 2    πŸ’¬ 3    πŸ“Œ 0
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Reviewing PhD Applications: A stream of consciousness β€” Gonzales Lab A list of notes takes in real-time when reviewing PhD applications and interviews

When reviewing PhD applications this cycle, I made small notes of things that stood out to me. Both good and bad.

I think it could be helpful to those considering applying this Fall.

gonzales.science/resource-blo...

22.04.2025 13:27 β€” πŸ‘ 16    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

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