Yale Center for RNA Science and Medicine

Love and RNA are in the air💗
Join us next Tuesday for this month's RNA Club
We have two exciting talks from Halene and @nicolilab.bsky.social labs, and as tradition, we’ll be serving fresh heart-shaped waffles🧇

📅Tuesday, February 10th at 8:45 AM
📍Hope 103, School of Medicine

Details in the flyer

Celebrate the legacy of RNA pioneer Sidney Altman

The 2026 Sid Altman Symposium honors his groundbreaking RNA discoveries and lasting impact as a scientist and mentor

Registration link in institutional email
Yale & affiliated institutions only

📧sidaltmansymposium@yale.edu

See you tomorrow for RNA club!

📽 G&D Tapes 📽

G&D Author, Alexandra Bergfort, tells us about their new study in #genesdev showing how the EJC coordinates splicing of exon blocks

Learn more:
➡️ https://genesdev.cshlp.org/content/40/1-2/94.full

Karla Neugebauer Alexandra Bergfort
Yale Center for RNA Science and Medicine
#splicing

Welcome back!
We’re kicking off the new year with our first Yale RNA Club of the season
📅Tuesday, January 13, 2026 | 9:00 AM
📍 Bass 305, Yale Science Hill
Talk details are in the flyer

Bagels, coffee, and tea will be provided
Open to the Yale community. We hope to see you there!

Remember to join us tomorrow for the RNA club at the Cohen Auditorium, School of Medicine ☃️

A winter-themed flyer for the December Yale RNA Club. At the top, large red text reads “Yale RNA Club” with snow accents. On the right, there is a smiling snowman wearing a top hat and bow tie. The schedule is listed on the left: 9:00 AM – Breakfast 9:15 AM – Yaru Xu (Mu Lab) presenting “Genome-wide CRISPRi Screening Identifies the LncRNA CRNDE as a Regulator of Lineage Plasticity and Drug Resistance in Prostate Cancer.” 9:45 AM – Je Won Yang (Noonan Lab) presenting “Conservation and divergence of mRNA stability and N6-methyladenosine RNA modification during human and chimpanzee neurodevelopment.” Another small snowman appears at the bottom left wearing a winter hat and scarf. Text at the bottom right reads: “9th December — Cohen Auditorium.” Footer includes organizer contact: Srikar Gopinath (srikar.gopinath@yale.edu) and the Yale Center for RNA Science and Medicine logo.

December RNA Club ❄️

Join us for the last RNA Club of the year.
📅Tuesday, December 9th at 9:00 AM
📍Cohen auditorium, Yale School of Medicine

Details in the flyer and the institutional email

Group photo, left to right, of Isabella Lawrence (Izzy), Dr. Guillermina Kubaczka (Guishi), Dr. Matt Simon, Ryan Stanton, and Dr. Srikar Gopinath — smiling together after the RNA Retreat.

What a day
Thank everyone who made the 13th Annual Yale RNA Center Retreat a success
Shoutout to our organizers, Ryan, Guishi, and Dr. Matt Simon, for leading this fantastic event for RNA scientists from Yale and UConn
Extra love to our angels, Srikar and Izzy, for helping keep everything on track!

ovember RNA Club 🍁 📅 Tuesday, November 11th at 9:00 AM 📍 TAC Auditorium (N107) Keep the RNA excitement going after the Retreat! Join us for coffee, bagels, and fresh RNA discoveries featuring: - Sudheesh Allikka Parambil (Van Wolfswinkel Lab) - Zhiping Zhang (Miura Lab, UConn) Don’t miss your chance to get your collectible stamp on your RNA Club card and enjoy another inspiring session of RNA science. Details in flyer below

November RNA Club 🍁

📅 Tuesday, November 11th at 9:00 AM
📍 TAC Auditorium (N107)

Keep the RNA excitement going after the Retreat!
Featuring:
-Sudheesh Allikka Parambil (Van Wolfswinkel Lab)
-Zhiping Zhang (Miura Lab, UConn)
Get your collectible stamp on your RNA Club card!

Details in flyer below

Reminder: This Friday, Nov 7, the 13th Annual Yale RNA Center Retreat

Registration: 8:30 AM

Looking forward to seeing you there!

Flyer titled “Special Symposium in Virus Biology in honor of Dr. Brett Lindenbach.” Event date: Friday, November 14, 2025. The flyer features two speaker portraits at the top: Dr. Ralf Bartenschlager (Heidelberg University & German Cancer Research Center), presenting “The cell biology of RNA virus replication: addicted to membranes and vulnerable to drugs.” Dr. Rudolf Beran (Gilead Sciences), presenting “HDV interplay with nuclear speckles.” Text notes that the event is sponsored by the Brett Lindenbach Virology Fund. Hosts: Anna Marie Pyle, Walther Mothes, Valerie Horsley, and Andrew Goodman. Contacts: francesca.benedetto@yale.edu

Happening soon at Yale! 🦠

Hosted by the Department of Cell Biology, the Brett Lindenbach Virology Symposium will be held on Friday, November 14, @ 12:30 PM.

Join for an exciting afternoon of talks on viral biology and therapeutic innovation.

Full schedule and details in the institutional email.

TDP-43 loss brings RNA to a twist ending - Nature Neuroscience In amyotrophic lateral sclerosis (ALS), nuclear depletion and cytoplasmic aggregation of the RNA-binding protein TDP-43 cause widespread dysregulation of mRNA splicing. Two recent studies have now rev...

New article @natneuro.nature.com by @yaleneuro.bsky.social Suzhou Yang & @kavliatyale.bsky.social Postdoc Fellow @zhenlei.bsky.social, highlighting studies by @frattalab.bsky.social Gitler & La Spada labs on the role of TDP-43 on mRNA 3' end in ALS @yalerna.bsky.social www.nature.com/articles/s41...

Flyer for a Yale Pathology Special Seminar. The top section shows the Yale Pathology logo and the tagline “Where Knowledge is Created and Shared.” Below, it reads: A Special Seminar Hosted by Pallavi Gopal, MD, PhD Wednesday, October 22nd, 3:00–4:00 PM ET 110 Hope, Hope Memorial Building (enter at 333 Cedar Street) Speaker: Nicolas Fawzi, PhD, Professor, Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University. Talk title: Dynamic Atomic Structures of RNA-Binding Protein TDP-43 – Drug Targets for ALS and Neurodegeneration. A portrait of Dr. Nicolas Fawzi appears on the lower left. The Yale School of Medicine, Department of Pathology logo appears at the bottom.

Special Seminar at Yale!

Dr. Nicolas Fawzi (Brown University) will be hosted by Dr. Pallavi Gopal on October 22.
Learn how RNA-binding proteins reveal new therapeutic insights into ALS and neurodegenerative disease

Details in the flyer and institutional email 👇

we are recruiting a postdoc with interest in using genomics and molecular biology to study transcription factors. We have an R35 to fund the project/salary.

Don't forget to join us tomorrow for the RNA Club!

🎟️ Don’t miss your chance to add a new stamp to your RNA Club card and keep the collection growing

Excited to see this beautiful art, commissioned from the Chinese artist 懒云居画 (@subaiweipainting on Instagram), on this month's cover of Nature Neuroscience! @natneuro.nature.com @yaleneuro.bsky.social @yalerna.bsky.social @kavliatyale.bsky.social @wutsaiyale.bsky.social

Flyer for the Yale RNA Club with a Halloween theme. The background is dark gray with decorative elements including bats, cobwebs, a witch hat, the words 'Spooky Witches,' ghosts, gravestones, spiders, black cats, and jack-o’-lanterns. Large green text at the top reads: 'Yale RNA Club.' Schedule is listed in bright green and white text: 9:00 AM – Breakfast 9:15 AM – Kumari Kavita Thakur, Breaker Lab. Talk title in italics: Ancient RNA Sensors Reveal New Guanidine Biology in Vertebrates 9:45 AM – Kyrillos Abdallah, Gilbert Lab. Talk title in italics: mRNA-specific translation initiation rates are tuned to prevent cellular stress At the bottom right, event details read: '14th October, Bass 305.' Contact information at the bottom left: 'Srikar Gopinath (srikar.gopinath@yale.edu

October RNA Club 🎃

Join us to explore some spooktacular discoveries in RNA. This month’s presentations feature:
🦇 Kumari Kavita Thakur (Breaker Lab)
🦇 Kyrillos Abdallah (Gilbert Lab)

Come, collect the next RNA Club collectible, and celebrate RNA science that’s anything but scary

Want to share your work with our RNA community? Submit your abstract by this Frday, September 26th, to be considered for a talk!

Flyer for the Yale RNA Science and Medicine 2025 Retreat. The title reads 'YALE CENTER FOR RNA SCIENCE AND MEDICINE' at the top. The event, named 'The 2025 Retreat,' will be held on November 7th at Yale's West Campus. Important deadlines are listed: trainee talk abstracts due by September 26th, and registrations and poster abstracts due by October 17th. The background is purple with text in white and dark purple. The bottom of the flyer features four molecular structures, likely representing RNA. A QR code is present on the right side of the flyer, likely for registration or event-related information

Save the Date!
2025 Yale RNA Center for Science and Medicine Retreat on Nov 7 @Grace Hopper Memorial Auditorium, West Campus

Deadlines:
Registration: Oct 17
Talk Abstracts: Sept 26
Poster Abstracts: Oct 17

👉Registration yalesurvey.ca1.qualtrics.com/jfe/form/SV_...
or using the QR code in the image

N6-methyladenosine promotes temozolomide resistance through non-canonical regulation of mRNA stability in glioblastoma cells N6-methyladenosine (m6A) is a critical regulator of mRNA processing and function, impacting nearly every step of the mRNA lifecycle. Changes in m6A status have been implicated in many different types ...

Thrilled to share a new preprint from the lab! We investigated how m6A regulates the transcriptome in chemoresistant glioblastoma through unexpected mechanisms, and the potential therapeutic applications of this discovery.
Check out the preprint here ⬇️
www.biorxiv.org/content/10.1...

Reminder: RNA Club kicks off tomorrow!

Join us Tuesday, Sept 9, at 9:00 AM in Bass 305

We’ll have two exciting talks, fresh bagels, coffee… and something new 👀
We’re starting a tradition this year, and let’s say: attendance has its perks. Don’t miss it!

Yale Study: Potential Treatment Pathway Found for Rare and Aggressive Leukemia A Yale study published Aug. 28 on the cover of the journal Blood explains basic scientific discoveries that could lead to innovative therapies for acute myeloid

Excited to share groundbreaking research from our members!

Researchers, including Dr. Stephanie Halene & Dr. Diane Krause, discovered a potential treatment pathway for aggressive leukemia, making it a possible target for the development of new therapies
Read more:
medicine.yale.edu/news-article...

Flyer for the Yale RNA Club, September 2025. The event is on Tuesday, September 9, 2025 at Bass Center 305, Yale Science Building. Breakfast and coffee at 9:00 AM, talks at 9:15 AM. Speakers: Clara Wang (Nachtergaele Lab) – “Investigating the role of the 18S rRNA m6A methyltransferase METTL5 in translation and metabolism”; and Xiaolin Niu (Ke Lab) – “Mechanistic insights into RNA targeting and cleavage by R-IscB and Cas13d.” Contact: Srikar Gopinath (srikar.gopinath@yale.edu). Flyer includes Yale RNA Center branding with autumn-themed colors.

✨ RNA Club is back! ✨

We’ve missed you and the great science talks!

Kick off the semester with us on Tuesday, September 9 at 9:00 AM in Bass Center 305, Yale Science Building.

Enjoy bagels & coffee plus exciting talks from Clara Wang and Dr. Xiaolin Niu.

Don’t miss it! 🧬

Reminder to register for the 2025 NYC RNA Symposium at Rockefeller University

Abstract deadline: September 1st

Looking for Job Opportunities?

Visit our website for opportunities within and outside Yale.
👉 lnkd.in/e2FwktQR

📢 Save the Date!
The 13th Yale RNA Center Annual Retreat returns this fall:
🗓️ November 7, 2025

Join us for a full day of cutting-edge RNA science and community.

Stay tuned for details on speakers, sessions, and registration.

📢 We are recruiting!
Several projects are available and can be tailored to the candidate's profile. Most include confocal imaging/spatial OMICs technologies.
Please share and RT 🙏

Flyer for the 2025 NYC RNA Symposium. The top features a hand-drawn NYC skyline with the Empire State Building, overlaid by a colorful RNA molecule. Text reads: “NYC RNA Symposium 2025.” Below: Tuesday, October 21st, 2025 The Rockefeller University Featuring: Roy Parker, PhD (UC Boulder/HHMI) & Christine Mayr, PhD (MSKCC) A yellow sticky note says: “Food and drinks will be served!” At the bottom: “FREE Registration” with a QR code and text: “Scan the QR code for more info.” Logos of sponsoring institutions include: New York Genome Center, Rockefeller University, Icahn School of Medicine at Mount Sinai, Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center, NYU, Albert Einstein College of Medicine, and Columbia University Irving Medical Center.

🗽Calling all RNA enthusiasts

2025 NYC RNA Symposium at Rockefeller University
📅 Tuesday, October 21st
-Keynotes: Roy Parker (UC Boulder/HHMI) & Christine Mayr (MSKCC)
-Short talks, poster & prizes
-Lunch & Happy hour
Free registration 👉 nycrnasymposium.com
Abstract deadline: September 1st

A cheerful selfie of four RNA community members during the Yale RNA Center summer celebration, holding drinks and smiling at the camera

Group photo of RNA researchers smiling at the Yale RNA Center summer party, standing in front of a columned patio

Five attendees of the Yale RNA Center summer party standing together smiling, with the event venue in the background

☀️That’s a wrap on our Midsummer RNA Dream Party!

From inspiring RNA-AI talks to Rose Garden celebration, it was the perfect way to close our semester. We’re grateful for this community of RNA enthusiasts. We look forward to reconnect in the fall

Until then… have a wonderful summer🧬🍦

The details are out —RNA meets AI at Yale!

Featuring: Rahul Satija, Silvi Rouskin, Hagen Tilgner, David Knowles & coffee, posters, +talks: RNA decay, variant prediction, ribosome recruitment

After🌸Midsummer RNA Dream Party
📅Add to calendar+register (Yale email)
medicine.yale.edu/rnacenter/ne...