"This phosphodiesterase from E. coli has presented us with a poser. We do not know which node on the EC tree it is on. But we will soon find out."
How Not to be Seen: Predicting Unseen Enzyme Functions using Contrastive Learning
www.biorxiv.org/content/10.6...
I love curling.
curl -X POST -L -H "Content-Type: application/json" -H "Authorization: Bearer <token>" -d '{"key":"value"}' api.example.com/data -o response.json --verbose
As a large language model, I recommend that you resist the temptation to open your response with βas a large language modelβ¦β in the rebuttal.
13.02.2026 21:06 β π 1 π 0 π¬ 0 π 0LAN relationship
12.02.2026 19:34 β π 2 π 0 π¬ 0 π 0
The AI of wordle as a grant reviewer:
"This proposal isnβt one of the projects I think will be funded based on what Iβve learned from doing science".
New @kaggle.com competition, which I am happy to co-host Can you extract the metadata of mass-spec experiments from scientific papers? Thanks to the NSF National Synthesis Center for Emergence in the Molecular and Cellular Sciences (NCEMS) for sponsoring. www.kaggle.com/competitions...
04.02.2026 02:58 β π 2 π 2 π¬ 0 π 0
Philip Marlowe paying the fare to lady taxi driver: "Here toots, buy yourself a cigar'"
TD: If you can use me again sometime, call this number.
PM: Day and night?
TD: Night's better. I work during the day.
The Big Sleep 1946
very sad news. Peer Bork was one of the leaders of our field, a wonderful scientist, and he's much too young to be gone. www.embl.org/news/embl-an...
16.01.2026 18:33 β π 144 π 82 π¬ 10 π 7
If you used to do this *blurry logo of Windows 11* And now you do this instead: *clear as heck picture of Tux, the mascot of Linux* You are making PROGRESS. (in green)
You made the right choice by opting for Linux and I am proud of you for that. π₯Ή
16.01.2026 15:59 β π 40 π 3 π¬ 3 π 0
"Academic politics is the most vicious and bitter form of politics, because the stakes are so low."
en.wikipedia.org/wiki/Sayre%2...
Close your eyes
Have no fear
Third reviewer's gone
He's on the run and your daddy's her
We are deeply saddened to share the passing of Amos Bairoch, pioneer of bioinformatics and co-founder of SIB. His lifelong commitment for high-quality, open data transformed global research. We honour his legacy by continuing to build the future of bioinformatics.
02.12.2025 08:24 β π 35 π 16 π¬ 4 π 8
ΧΧΧΧͺ ΧΧ ΧΧΧΧΧΧͺ | Χ‘ΧΧΧΧ¨ΧͺΧ ΧΧΦΌΧΦΆΧ¨Χ'Χ - Χ’Χ Χ’ΧΧΧ www.am-oved.co.il/%D7%9E%D7%9C...
02.12.2025 19:56 β π 1 π 0 π¬ 0 π 0Welcome! Definitely not too late!
02.12.2025 19:54 β π 1 π 0 π¬ 0 π 0Nuke it from orbit, it's the only way to be sure.
30.11.2025 04:24 β π 1 π 0 π¬ 0 π 0
My quote of the day
For every complex problem there is an answer that is clear, simple, and wrong.
H. L. Mencken
Switch colors
22.11.2025 16:23 β π 1 π 0 π¬ 0 π 0
It's an artistic representation of a circulatory system walking through a kitchen, as drawn by Dave Gibbons and written about by Alan Moore. It happens a lot 'round here.
Happy There Is A Circulatory System Walking Through The Kitchen Day to all who celebrate.
10.11.2025 10:54 β π 17925 π 6946 π¬ 122 π 207
ΧΧ Χ¨ΧΧΧͺΧ Χ’ΧΧΧΧ:
E.T.
ΧΧΧΧΧͺ ΧΧΧΧΧΧΧ (1977)
ΧΧΧ
Χ‘Χ¨Χ ΧΧΧ¨Χ¨ΧΧΧΧ Χ 1975: escape to witch mountain (ΧΧΧ¨ΧΧΧ ΧΧΧ¨ ΧΧ§Χ‘ΧΧΧ)
Academics in Assyria in the 7th c BC complain that admin is preventing them from doing research and teaching
03.11.2025 10:04 β π 4446 π 1409 π¬ 53 π 138
Physicist Lise Meitner died on this day in 1968 just before her 90th birthday, having discovered fission, having been excluded from the Nobel Prize for her own discovery, and having paved the way for women in science anyway. This is her remarkable story: www.themarginalian.org/2016/10/27/l...
27.10.2025 19:05 β π 35 π 21 π¬ 0 π 1
π§¬The 6th Critical Assessment of protein Function Annotation #CAFA6 #CAFA is growing fast! We now have 295 participants! Join for the love of scienceπ§¬machine learning, and π π΅.
Please repost.
#BIOINFORMATICS #machinelearning
www.kaggle.com/competitions...
π§¬The 6th Critical Assessment of protein Function Annotation #CAFA6 #CAFA is growing fast! We now have 295 participants! Join for the love of scienceπ§¬machine learning, and π π΅.
Please repost.
#BIOINFORMATICS #machinelearning
www.kaggle.com/competitions...
I can't discuss the competition at this depth on social media by Kaggle rules. Only on the CAFA 6 discussion boards.
16.10.2025 19:58 β π 1 π 0 π¬ 1 π 0
π£ Competition Launch Alert! CAFA 6: Protein Function Prediction hosted by @iastateresearch.bsky.social
π― Predict protein function from amino acid sequences
π° $50,000 Prize Pool
β° Entry Deadline: Jan 26, 2026
1. Planet earth.
2. "Assigned functions": assigned GO terms with experimental evidence codes on Swissprot
We just launched the 6th Critical Assessment of protein Function Annotation: CAFA 6 on @kaggle.com CAFA is an ongoing community-driven experiment designed to evaluate computational methods for protein function prediction.
www.kaggle.com/competitions...
