David Berman's Avatar

David Berman

@docterbman.bsky.social

Humble Human, Genitourinary Pathologist and Scientist. Obsessed with coffee.

442 Followers  |  433 Following  |  145 Posts  |  Joined: 16.11.2024  |  2.2921

Latest posts by docterbman.bsky.social on Bluesky

Visit uscap.org/smedia for details.

20.05.2025 01:18 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Laboratory Investigation seeks a Social Media Editor.
Are you an MD or PhD with expertise in basic, translational, or anatomic pathology who has experience creating social media posts? @rovingatuscap.bsky.social @uscap.org @anirbanmaitra.bsky.social @katcollmd.bsky.social Link in Comments

20.05.2025 01:16 β€” πŸ‘ 5    πŸ” 3    πŸ’¬ 1    πŸ“Œ 1
Post image Post image Post image Post image

#slidearchiveseries urothelial carcinoma, clear cell (glycogen-rich) #gupath

🎨 IHC profile similar to conventional urothelial carcinoma (GATA3, p63)
⚠️ distinguish from metastatic CCRCC and clear cell adenocarcinoma

29.03.2025 15:38 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

These are quite fun. Highly recommended.

08.03.2025 00:07 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

At once, pretty and frightening

06.01.2025 16:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Wow, that's some brisk inflammation! Far more intense than a typical circumcision specimen. Thanks for sharing this case.

05.01.2025 21:36 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Well done! Thank you for this important work. As a pathologist who issues many prostate cancer reports, I would love to see examples of your PCPR reports. Unfortunately, the supplemental information published does not include them.

04.01.2025 13:28 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Or if you don't want to purchase a 21 year old book, just consider taking large-ish sections at the distal margin and shaving a small strip of urothelium at the proximal margins.

29.12.2024 15:31 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Surgical Pathology Dissection An Illustrated Guide by Westra, William H., Hruban, Ralph H., Phelps, Timothy H., Is [Springer,2003] (Paperback) 2nd Edition Surgical Pathology Dissection An Illustrated Guide by Westra, William H., Hruban, Ralph H., Phelps, Timothy H., Is. Published by Springer,2003, Paperback 2nd Edition

Beautiful technique and review of gross anatomy. One consideration from someone who has signed out hundreds of RPs: A more parsimonious approach to the distal and proximal margins can conserve resources and make it easier to localize + margins. See www.amazon.com/Surgical-Pat...

29.12.2024 15:28 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Love it.

24.12.2024 18:35 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Finnish Scholars said that Frontiers and MDPI journals β€œmake use of the APC (Article Processing Charge) operating model and aim to increase the number of publications with the minimum time spend for editorial work and quality assessment.”

24.12.2024 18:32 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

An offensive infestation of ads.

12.12.2024 23:10 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Well done, and looking sharp.

12.12.2024 23:06 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

This is an old post from Twitter. A few years later, we now have the technology to include "sanitized" PDF reviews for authors and editors to read.

12.12.2024 02:32 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Congratulations, indeed!

11.12.2024 01:42 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

The biohazard folks will be jellin.

10.12.2024 11:50 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Today's library highlight: laryngeal carcinoma cells. Wood carving, Lionel Beale (1861).

09.12.2024 19:18 β€” πŸ‘ 8    πŸ” 4    πŸ’¬ 2    πŸ“Œ 0

Hot take #NephSky if you order a renal biopsy and are not willing or available to talk to the renal pathologist, why have you ordered this test?

The power of the renal biopsy is an exercise in clinico-pathologic correlation, it doesn’t work as other lab tests.

07.12.2024 15:25 β€” πŸ‘ 16    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Preview
After a shocking shooting, Americans vent feelings about health insurance β€” NPR The death of UnitedHealthcare CEO Brian Thompson triggered a deluge of painful stories about health care denials on social media.

Brian Thompson’s assassination is a horrifying and tragic. But maybe something good will come of this renewed conversation about an industry whose _entire_ business model has been based for decades on profiting at the expense of patients and providers.

apple.news/ASy_o_WGXRI6...

06.12.2024 14:53 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

More #pathsky

05.12.2024 23:07 β€” πŸ‘ 8    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

So then the question becomes, what year will I leave X/twitter? 2025?

05.12.2024 21:58 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

#pathsky. I like it!

05.12.2024 12:11 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

We definitely got the creative juices flowing. Please follow the @uscap.org account for news from these two fine #pathbluesky (is that a thing? If not, it should be) journals.

04.12.2024 22:32 β€” πŸ‘ 10    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

With the ongoing migration of #medtwitter to Bluesky πŸ¦‹- crucial that we amplify messaging for 2024 #HCWvsHunger campaign - please join the efforts! #PathSky
@kmirza.bsky.social @smlungpathguy.bsky.social @ihc-guy.bsky.social @ljtafe.bsky.social @anirbanmaitra.bsky.social @drfna.bsky.social

02.12.2024 16:51 β€” πŸ‘ 7    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

πŸ§ͺDear Grad student,

Are you overdue for a thesis committee meeting but feel like you have nothing to show since your last meeting? I'm begging you to schedule that meeting now!

1/🧡

29.11.2024 21:28 β€” πŸ‘ 216    πŸ” 63    πŸ’¬ 6    πŸ“Œ 11

Add me please and thank you.

16.11.2024 22:37 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Snow Sentinels on Lake Ontario. #YGK

26.12.2022 20:33 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
When emails asking to withdraw manuscripts started repeating themselves, an editor got suspicious Photo by Bilal Kamoon via flickr In late 2021, editors at Laboratory Investigation noticed something strange. The journal was receiving far more emails than usual asking to withdraw manuscripts tha…

Managing Editor @cmketcham finds and ponders penalties for authors who submit their papers to multiple journals at once. #FAFO. @LIjournal and @ModernPathology @DrNetto

retractionwatch.com/2022/09/30/whe…

15.11.2022 19:21 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Elevated HLA-E and NKG2A as a consequence of chronic immune activation defines resistance to M. bovis BCG immunotherapy in Non-Muscle-Invasive Bladder Cancer Mycobacterium bovis Bacillus Calmette-Guerin (BCG), the first line treatment for non-muscle invasive bladder cancer (NMIBC), promotes production of type I interferons, particularly interferon (IFN)-Ξ³. Prolonged inflammation and IFN-Ξ³ exposure are known to cause an adaptive immune response, enabling immune escape and proliferation by tumor cells. We investigated HLA-E and NKG2A, a novel T and NK cell checkpoint pathway, as a driver of adaptive resistance in BCG unresponsive NMIBC. We observed ubiquitous inflammation in all patients after BCG immunotherapy, regardless of recurrence status. IFN-Ξ³ was shown to drive tumor expression of HLA-E and PD-L1. Further, NKG2A-expressing NK and CD8 T cells were enriched in BCG unresponsive tumors and with enhanced capacity for cytolytic functions. Strikingly, in situ spatial analyses revealed that HLA-EBRIGHT tumors are activated to recruit NK and T cells via chemokine production potentially sparing HLA-EDIM/NEG tumors that would otherwise be susceptible to lysis. Finally, blood-derived NK cells retained antitumor functions at time of tumor recurrence. These data support combined NKG2A and PD-L1 blockade for BCG unresponsive disease. ### Competing Interest Statement The authors have declared no competing interest.

Terrific talk by @AmirHorowitz video-cast to @IBCN1997 this a.m. describing work w/ @DrJohnSfakianos. Upregulation of HLA-E and NKG2A in BCG-unresponsive cancers. An exciting immune checkpoint ligand-receptor pair. Promise for Rx and Dx. Preprint here:

biorxiv.org/content/10.110…

01.10.2022 12:34 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Hey @Zoom Can your engineers design an updating system that doesn't make everyone late for their meetings?

27.07.2022 17:21 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

@docterbman is following 20 prominent accounts