Nicolas Minc

📣 New preprint from the @minclab.bsky.social

📃 A CROSS-SPECIES ANALYSIS OF CELL WALL MECHANOSENSORS
🔗 www.biorxiv.org/content/10.1...

Decreased cytoplasmic crowding via inhibition of ribosome biogenesis can trigger Candida albicans filamentous growth Nature Microbiology - During filamentous growth in the human fungal pathogen Candida albicans, a reduction in ribosome concentration leads to a decrease in macromolecular crowding. Inhibition of...

👉Excited to share our latest work @natmicrobiol.nature.com, revealing a decrease in cytoplasmic crowding during filamentous growth in the human fungal pathogen Candida albicans. Furthermore we found that inhibition of ribosome biogenesis can trigger filamentous growth in this pathogen
rdcu.be/eT1Su

Incredibly excited to receive an ERC Consolidator Grant. This recognition means a lot for what we’ve built so far and for what’s ahead.

Thank you to all collaborators and supporters.

Looking forward to getting this project going!

6 cellules d'oursins adoptant des formes différentes à cause du moule dans lequel elle se trouve : rond, conique, étoilé, carré, rectangulaire et bâtonnet. Tiré d'une étude de Nicolas Minc "Influence of Cell Geometry on Division-Plane Positioning"

Pour la dernière émission de @podcastscience.fm www.podcastscience.fm/emission/202... dont le thème était le carré, j'ai réalisé une chronique où je parle des travaux de @minclab.bsky.social ( @ijmonod.bsky.social ) qui met les cellules en boîte!
À lire et écouter sur SSAFT
ssaft.com/Blog/dotclea...

Tissue stress measurements with Bayesian Inversion Stress Microscopy Cells within biological tissue are constantly subjected to dynamic mechanical forces. Measuring the internal stress of tissues has proven crucial for our understanding of the role of mechanical forces...

Tissue stress measurements — our latest preprint is out: arxiv.org/abs/2512.00550
(publication coming soon!)
Fantastic work by the three musketeers — @luanger.bsky.social, @andreasschoenit.bsky.social and @fanny-wodrascka.bsky.social — in collaboration with P. Marcq!

Above: transverse sections of neurulating chick embryos stained for DNA (methyl green) and F-actin (TRITC-phalloidin), without and with the addition of the phorbol ester PMA. Below: computational simulations of pseudostratified epithelia, with different apicobasal/lateral tension ratios. Either PMA treatment in embryos, or lower ratios in simulations, cause epithelial instability evidenced by extensive cell extrusion.

Paper alert! Mechanical conditions preventing live cell extrusion during primary neurulation in amniotes. @sabr-bio.bsky.social article published as pre-proof in @cellsdev.bsky.social! doi.org/10.1016/j.cd...

Anthony A. Hyman will become EMBL’s next Director General.

He joins EMBL from @mpi-cbg.de in Dresden. He is also Professor of Molecular Biology @tudresden.bsky.social, and was a group leader at EMBL Heidelberg from 1993 to 1999.

www.embl.org/news/people-...

We are looking to hire a postdoc to work on the regulation of microtubule nucleation in neurons. See advert attached. Contact me by email for any extra info.

#JobOffer

💼 Ingénieur de recherche H/F en biophysique de l'infection bactérienne
📆 12 Janvier 2026
📍équipe Bonazzi

Candidatez sur le portail emploi CNRS avant le 15 décembre 🔗 emploi.cnrs.fr/Offres/CDD/U...

bravo romain!!!

✍️ The Pintard Lab ( @ccdlab.bsky.social ) published a new article

📖 @jcb.org
📃 Intramolecular regulation of the MT-severing enzyme Katanin prevents futile ATP hydrolysis

🔗 rupress.org/jcb/article-...

Congratulations to Celia Municio-Diaz in the lab for this new publication, showing that Cell Wall mechanosensors taken from distant yeast species can still function and detect forces in the foreign cell wall of fission yeast cells!

@ijmonod.bsky.social @cnrsbiologie.bsky.social

A ubiquitin-like protein controls assembly of a bacterial type VIIb secretion system Cryo-EM structure reveals how a ubiquitin-like protein orchestrates assembly of a bacterial weapon system.

Our latest T7SS study is now out in Science Advances!
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.

www.science.org/doi/10.1126/...

HAK-actin, U-ExM-compatible probe to image the actin cytoskeleton - preLights HAK-actin is a new probe that may help researchers see the actin cytoskeleton in sharper detail using expansion microscopy.

Reliable actin labelling in expansion #microscopy 🔬

Beautiful #preprint from Olivier Mercey, @lreymond.bsky.social & team @dudinlab.bsky.social @centriolelab.bsky.social

Read the latest #preLight from @kanishka03.bsky.social ⬇️👀
prelights.biologists.com/highlights/h...

📣 The Institut Jacques Monod congratulates Stéphane Nedelec ( @spinalorga.bsky.social ) on receiving the @erc.europa.eu Synergy Grant!

More informations 🔗 erc.europa.eu/news-events/...

@cnrs.fr @upcite.bsky.social @institutcurie.bsky.social @inserm.fr

A Python framework for magnetic tweezers real-time image processing and microscope control https://www.biorxiv.org/content/10.1101/2025.10.31.685671v1

🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky

www.cell.com/cell/fulltex...

Spread the word! There is a professor position opening at our University @upcite.bsky.social. There are several possible (great) labs to join, but if you are interested in DNA methylation and epigenetics in mammals, don't hesitate to contact me directly!

#JobOffer

💼 Un poste susceptible d’être vacant de Professeur en stabilité des génomes devrait s’ouvrir pour la rentrée 2026 au sein de l’Institut Jacques Monod

➡️ Informations concernant ce poste et la procédure de candidature 🔗 www.ijm.fr/poste-de-pro...

✍️ The Dumont Lab published a new article with contributions from the @minclab.bsky.social Lab

📖 @jcb.org
📃 Mechanical coordination between anaphase A and B drives asymmetric chromosome segregation
🔗 rupress.org/jcb/article-...

In @jcb.org, Dias Maia Henriques, Dumont, Maton et al. @ijmonod.bsky.social uncover an #anaphase A pathway, driven by the #kinesin-13 KLP-7 and opposed by the kinesin-12 KLP-18, that contributes to chromosome segregation in early #Celegans embryos. rupress.org/jcb/article/...

#Mitosis #Spindle

#JobOffer

💼 Post-doc in cell biology and genomics in C. elegans (M/F)
📆 January 5th, 2026
📍Institut Jacques Monod, Dumont Lab

Apply before November 7th 🔗 emploi.cnrs.fr/Offres/CDD/U...

#JobOffer

💼 Postdoctoral Researcher (M/F) in Biophysics of Bacterial Infection
📆 January 1st, 2026
📍Institut Jacques Monod, Bonazzi Lab

Apply before November 6th 🔗 emploi.cnrs.fr/Offres/CDD/U...

Dias Maia Henriques, Dumont, Maton et al. @ijmonod.bsky.social uncover an #anaphase A pathway, driven by the #kinesin-13 KLP-7 and opposed by the kinesin-12 KLP-18, that contributes to chromosome segregation in early #Celegans embryos. rupress.org/jcb/article/...

#Mitosis #CellDivision #Spindle

A histone methyltransferase-independent function of PRC2 controls small RNA dynamics during programmed DNA elimination in Paramecium Abstract. To limit transposable element (TE) mobilization, most eukaryotes have evolved small RNAs to silence TE activity via homology-dependent mechanisms

Our latest paper on a histone methyltransferase-independent function of PRC2 controlling small RNA dynamics during programmed DNA elimination in Paramecium is now published in #NAR.
#RNAbiology #TEsky #smallRNAs #PRC2 #DNAelimination
1/5
academic.oup.com/nar/article-...

In the foreground, an audience is seated, seen from behind. They are attending a talk by Nicolas Minc, a man with short dark hair wearing a light blue shirt. He is presenting a title slide that reads "How large cells do it? Cytoplasm mechanics and division positioning"

We had a full room today for a talk by Nicolas Minc @minclab.bsky.social from @ijmonod.bsky.social 👏 He presented his team's latest work on the mechanics of cell division, including how they use magnetic tweezers to rotate mitotic spindles 💥 Thank you for joining us!

Thanks for inviting, really enjoyed my stay !!

We hire!
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...

✍️ The Léon Lab and ProtéoSeine platform published a new article
📖 @plos.org genetics
📃 A genetic screen reveals a key role for Reg1 in 2-deoxyglucose sensing and yeast AMPK inhibition

🔗 journals.plos.org/plosgenetics...

Research engineer in Bioimage Analysis for the researchers of the inIdEx FORMULA Hi all We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks? The position is in the Instit...

Job alert!

We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks?

See also on the forum:
forum.image.sc/t/research-e...