A stride towards a better liver model
By altering the growth environment, the Huch lab at MPI-CBG has developed a liver model that extensively mimics the heterogeneity of the real organ.
By altering the growth environment, the group of @merihuchlab.bsky.social @mpi-cbg.de with first authors Javier Bregante & Flaminia Kaluthantrige has developed a liver model that extensively mimics the heterogeneity of the real organ. @cp-cellreports.bsky.social. www.mpi-cbg.de/news-outreac...
05.03.2026 09:27 —
👍 5
🔁 2
💬 1
📌 1
Amazing!!!
05.03.2026 06:22 —
👍 1
🔁 0
💬 0
📌 0
🤩to see this behemoth of a story out !
Pushed by @nikobiota.bsky.social & the Amazing @embl.org AML Team (Tina, Michael, Paulina) and in Co. with the Best #science #family you can dream of!
This truck was #home, for weeks in a row & in my heart for a lifetime.
www.biorxiv.org/content/10.6...
24.02.2026 16:49 —
👍 47
🔁 11
💬 4
📌 0
well... I have thoughts. @leventallab.bsky.social will have thoughts too. @jamessaenz.bsky.social and @lipid.bsky.social might as well. @ibudin.bsky.social ...
04.03.2026 19:18 —
👍 0
🔁 0
💬 0
📌 0
Ever wondered how to quantify the spatial relationship between different species (eg cell co/trilocalisation)? Lovely working with this interdisciplinary team — math @nerdarajan.bsky.social @tomchaplin.xyz @majirouses.bsky.social meets oncology @leedham-simon.bsky.social @joshuabull.bsky.social
04.03.2026 05:14 —
👍 2
🔁 1
💬 0
📌 0
This is a fantastic #biophysics job opportunity to join us in Dresden @mpipks.bsky.social! Apply by the 3rd of April!
03.03.2026 13:15 —
👍 13
🔁 6
💬 0
📌 0
We are very excited to share a new resource from our team: spatial subcellular proteome maps in plants! We developed an MS-based method that registers localizations of about 8000 proteins in Arabidopsis roots in a single experiment.
(1/9)
www.biorxiv.org/cgi/content/...
03.03.2026 06:53 —
👍 111
🔁 68
💬 2
📌 1
This is wonderful work - Congratulations!!!
27.02.2026 13:55 —
👍 2
🔁 0
💬 1
📌 0
Redirecting
Our most recent work on the “function and evolution” of #nuclear-speckles is now online at Cell @cp-cell.bsky.social
doi.org/10.1016/j.ce...
Read the thread👇 for the highlights of our findings.
25.02.2026 16:01 —
👍 121
🔁 59
💬 9
📌 5
That seems to be an important protein - congrats!
26.02.2026 22:05 —
👍 0
🔁 0
💬 0
📌 0
CLCC1 governs ER bilayer equilibration to maintain lipid homeostasis - Nature
Phospholipid scrambling at the endoplasmic reticulum is essential for establishing a dynamic equilibrium to maintain cellular homeostasis.
Excited to share what we uncovered using in-tissue cryo-ET in mouse liver: a structural snapshot of lipid droplet biogenesis in situ. Timely reading—particularly after a lipid-rich Chinese New Year😂 The lipid homeostasis story governed by CLCC1 with more details here: www.nature.com/articles/s41...
26.02.2026 10:29 —
👍 14
🔁 4
💬 1
📌 0
We’re recruiting new Research Group Leaders!
We offer:
🔬 Core funding
💻 Access to world-leading infrastructure
👩🏽🔬A network of world-leading scientists
…and much more.
Apply by 11 April: embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
#ResearchCareers #Bioinformatics @timcoorens.bsky.social @embl.org
25.02.2026 10:24 —
👍 20
🔁 20
💬 0
📌 1
Affinity Above All?
An argument that medicinal chemists should spend more effort on making more potent compounds:
25.02.2026 21:25 —
👍 19
🔁 7
💬 1
📌 2
What a stunner. And what a plot twist halfway through. This is a truly amazing story. Congratulations!!
25.02.2026 21:01 —
👍 8
🔁 0
💬 1
📌 0
Maybe so but I very much doubt that it helps you getting the grant. Paying external consultants for ERC grant applications is a fool's errant.
25.02.2026 09:36 —
👍 0
🔁 0
💬 0
📌 0
For ERCs I would doubt that. For other parts of the portfolio it is certainly true.
24.02.2026 20:17 —
👍 0
🔁 0
💬 2
📌 0
29 minutes from stepping out of the door at home to the gate at Dresden airport. Must be a record. Side note (i): Record was set between 4:35 and 5:04 local time. Side note (ii): No, our airport is not profitable. 🤪 On my way to #BPS2026 in San Francisco & looking forward to meeting everybody!
22.02.2026 04:22 —
👍 16
🔁 0
💬 0
📌 0
The origin of life wasn't fat-free
James Sáenz studies how fatty molecules might have helped life get started
Lipids are kind of the ignored middle children of origins of life research. It's time they got a bit of attention, too!
This week's post is a Q&A with geoscientist-turned-??? (interdisciplinary folks know the struggle) @jamessaenz.bsky.social about why there's no cutting the fat from origins. 🧪
19.02.2026 16:57 —
👍 44
🔁 18
💬 4
📌 5
This will feature an #EPIC scientific program. Something you have not seen before. Trust me 😉 CBG Alumni of all nations, unite!
18.02.2026 16:23 —
👍 15
🔁 5
💬 1
📌 1
This is going to be SPECTACULAR!!! the meeting to end all meetings, the party to...
18.02.2026 17:49 —
👍 5
🔁 0
💬 0
📌 0
It is. Unless you are dumb & turn it into 3.5 hrs
18.02.2026 11:14 —
👍 0
🔁 0
💬 0
📌 0
No, everybody living in the middle remains in the hands of @deutschebahn.com. No stops between Neustadt and Südkreuz. Sorry!
18.02.2026 10:42 —
👍 1
🔁 0
💬 1
📌 0
I have 28 minutes from Südkreuz to Harnack house... doable. But no lunch...
18.02.2026 10:40 —
👍 0
🔁 0
💬 0
📌 0
Should have linked @ceskedrahyofficial.bsky.social. You guys are great! Can you please buy @deutschebahn.com and, well, tell them what to do?
18.02.2026 10:15 —
👍 2
🔁 0
💬 0
📌 0
So, I made a mistake today. There is a wonderful Dresden-Berlin train connection that is operated by the Czech railway. Dumb me booked the alternate @deutschebahn.com connection. Train cancelled, of course. Two hours at Dresden Hbf. Now on Czech train. #Shouldknowbetterbynow
18.02.2026 10:09 —
👍 8
🔁 0
💬 3
📌 0
Cool stuff. I am a fan 😍
17.02.2026 14:28 —
👍 5
🔁 1
💬 1
📌 0
During #NeuronalDifferentiation, #organelles dramatically reorganize. #Microtubules are essential tracks for transport. But are they just highways, or can they instruct organelle behavior? Are tubulin modifications a regulatory code that guides organelle position or function? 1/9
16.02.2026 22:32 —
👍 27
🔁 12
💬 1
📌 2
I'm delighted to present TWO new preprints from my lab, led by @mczanellati.bsky.social and @sherryhsu.bsky.social, about how #organelles remodel throughout #NeuronalDifferentiation. Check out the threads about their papers below:
16.02.2026 22:41 —
👍 19
🔁 7
💬 2
📌 0