Unraveling microglial spatial organization in the developing human brain with DeepCellMap, a deep learning approach coupled with spatial statistics - Nature Communications DeepCellMap, a deep-learning tool, maps microglial organisation in the developing brain, revealing their spatial diversity, clustering patterns, and associations with blood vessels. DeepCellMap is ava...

Huge congratulations to @davidmenassa.bsky.social and all co-authors for developing and publishing DeepCellMap - a new algorithm allowing the spatial characterisation of microglia in health and disease! We are very proud to be a part of this fantastic work 🥳

www.nature.com/articles/s41...

Genomic tumor evolution dictates human medulloblastoma progression AbstractBackground. Medulloblastoma (MB) is the most common high-grade pediatric brain tumor, comprised of 4 main molecular subgroups—sonic-hedgehog (SHH),

Our single-cell study of medulloblastoma with our PhD student @yanaruchiy.bsky.social as a first author is now in print 🥳 Check it out!

academic.oup.com/noa/article/...

Rapid and robust isolation of microglia and vascular cells from brain subregions for integrative single-cell analyses - PubMed Cell isolation protocols from brain tissue include prolonged <i>ex vivo</i> processing durations, rendering them suboptimal for transcriptomic studies. Particularly for microglia and vascular cells, c...

Check out our recent paper where we describe our newly developed method of isolating microglia and vascular cells for single-cell sequencing!

pubmed.ncbi.nlm.nih.gov/39211933/