Abdel Rahman Abdel Fattah

@epimechfc.bsky.social discussion with @dedenonmathieu.bsky.social at #CellMech2025 :)

What an incredible #cellmech2025 packed with science, ideas, and inspiration! 🚀 We loved sharing our work on ECM dynamics, mechanics & energy consumption in early development (Dunja Al-Nuaimi & Sowmya Sunkara). Grateful for this vibrant community ➡️ see you at CellMech 2027!

#BloodBrainBarrier

"microglia are not necessary for the maintenance of BBB structure, function, or gene expression in the healthy brain"

Evidence from >95% microglia depletion by PLX5622, a CSF1R inhibitor (1 mo) & BBB ultrastructure

@cprofaci.bsky.social #Neuron 2024
www.cell.com/neuron/fullt...

🚨Preprint alert!🚨 Very happy that our lab could contribute to this new aging story by the @lderooij.bsky.social group, building a Human Aging Atlas with over 375,000 profiled endothelial cells, so many insights including a mechanical twist to our aging endothelium.

On 7–8 July, CeMM Recess 2025 brought our postdoc community together!👩‍🔬👨🏾‍🔬

From scientific talks to bold science pitches, feedback, & evening quiz, a retreat full of ideas & inspiration!

Thanks to organisers Barbara Maier, @ar-abdelfattah.bsky.social, @dseruggia.bsky.social, & to all who joined! 👏

🔬 As we near the end of #EquationsForLife, today we spotlight @ar-abdelfattah.bsky.social's Group!
They use the #ReactionDiffussion equation to characterize the process of tissue organization and maintenance in physiology, and how disease disrupts it.
🔎 bit.ly/4ef2Pbe

sketch of tissues

What’s the link between Origami and morphogenesis?

This is the world of Actuation, I’m @ar-abdelfattah.bsky.social, and I’ll share with you insights, experiments and an outlook on how epithelia use mechanical forces to gain geometrical and functional complexity.

very nice and comprehensive. methods to assess tissue stress. thanks for compiling this.

a very important tool for #ECMatrix enthusiasts!! I'm sure this will come in handy for many researchers.

Huge congrats Christa, this is amazing!!!

thanks!

Thanks Christa!! :)

Thanks Wouter!!

A very informative thread on this emerging field, the metabolic dimension of #mechanobiology!! nicely done.

Thanks so much Diana.. 😊😊!

Thanks Sylvain!

Thanks Julia!!

Our #TBI project got funded! Driven by what happens when forces are too much to handle, we will engineer tools to traumatize organoids and focus on #ECMatrix dynamics, #mechanobiology, and molecular-to-multicellular tissue organization. Happy to collaborate! Happening @ CeMM

Congrats Wouter!

Differential stiffness between brain vasculature and parenchyma promotes metastatic infiltration through vessel co-option - Nature Cell Biology Uroz et al. report that the distinct mechanical properties of brain vasculature versus parenchyma drive cancer cell migration through a talin-dependent mechanism, enabling vessel co-option and metasta...

Hi #cancer, #ECMatrix, #biomaterials and #mechanobiology folks:
Below a Nat Cell Biol paper from the Chen and Weaver groups, of interest to many of us 🧪👇:

www.nature.com/articles/s41...

👋Hello #mechanobiology community!

Next year we are organizing the CellMech conference in Leuven!

We will soon be announcing (super amazing) invited speakers, registration deadlines, etc

I'll try to keep the🦋community updated, but best is to subscribe to the mailing list 📧👇

cellmech2025.org

Let's make this community even stronger! join, spread the word.

Great initiative can you please add me.

Interested in metal transporters, #SLC, metal toxicity? check out the amazing work of Andrè Ferdigg from @supertifurgalab.bsky.social 👇

Amazing group, please add me!

Pre-announcing the EMBO/EMBL symposium "Mechanobiology Across the Tree of Life", Heidelberg, 9-12 June 2026. It is still very very far away, but save the date 🗓️. With Alba Diz-Munoz, @nicolettapetridou.bsky.social , Kirsty Wan @micromotility.bsky.social, Enrique Rojas.
www.embl.org/about/info/c...

Amazing, can't wait to visit again!

If you're interested in magnetic actuation and #mechanobiology, this is a very nice review! 🧲⚙️🧫

@bioeng-talk.bsky.social is posting here as well! Speaking of moving to new places (🦋), in this episode, a bunch of us discuss why we moved to Europe to continue our academic careers. Tune in to hear about our experiences and what motivated us to make the leap.

Excited to join the 🦋 community, and even more excited to share that the lab has its very own logo & website! 🖥️🔎 Visit us at derooijlab.org to explore our work, stay updated on ongoing projects, papers, and more!