Amanda Oakie

(1/2) 🇨🇦 Canada changed the world with the discovery of insulin — and 40 years later, with #StemCells, launched #RegenerativeMedicine.

Today, another breakthrough is within reach.

Postdoctoral Researcher

📢 Exciting job opportunity!

The Epelman Lab at University Health Network is hiring a Postdoctoral Researcher in #Cardiology to study engineered heart tissue, tissue regeneration, and macrophage biology. 🫀

Learn more and apply! ➡️ stemcellnetwork.ca/career-oppor...

Assistant Professor (Tenure-Track)

📢 McGill University is hiring!

A tenure-track Assistant Professor position is open in Pluripotent Stem Cells in Regenerative Medicine, within the Department of Pharmacology and Therapeutics, in partnership with the Meakins-Christie Labs at the RI-MUHC.

Apply. ➡️ stemcellnetwork.ca/wp-content/u...

Cake

Celebrating 600

Islets for research

Yesterday we celebrated our 600th human research islet isolation in support of diabetes research (and then last night isolated the islets in the pic). I’m very fortunate to work with such a dedicated team! See more at www.isletcore.ca

I have gotten a bit behind at sharing the lab’s latest work - this paper is now published - check it out! www.cell.com/cell-reports... Long story short: insulin is the major determinant of female fat storage, with a relatively minor effect on males.

Save the date for the 2026 A-BC Islet Biology meeting! Looking forward to many fantastic presentations by trainees in islet biology from all over Canada as well as great keynote lectures. Please share widely! isletmeeting.weebly.com

Image of Toronto

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.

www.nature.com/naturecareer...

Please repost!

Discover MyRoad, a platform dedicated to research training and mentorship in the fields of obesity, diabetes, and cardiometabolic diseases. New opportunities are available this fall, including cohort-based training, travel awards, and health research exchange competitions. www.myroadplatform.ca/en

The @calvin-ke.bsky.social lab is hiring a Postdoctoral Fellow! Apply to join the team, where you will lead community-engaged, equity-focused type 2 diabetes research (qualitative & mixed-methods). jobs.smartrecruiters.com/UniversityHe...

Very proud to share the first review from the lab with contributions of all lab members. Writing this gave our new lab opportunity to read and discuss many papers and grow as a team. www.frontiersin.org/journals/imm...

👇👇👇

Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication Tong et al. utilize advanced imaging approaches to reveal that beta cells located next to alpha cells are specially adapted as glucagon sensors by virtue of their high expression levels of GLP1R. Thes...

A regulated pathway through which glucagon modulates insulin release via alpha to beta cell communication and control of GLP-1R internalization and beta cell Ca2+ responses to high glucose @cp-cellmetabolism.bsky.social @daveyboyhod.bsky.social #islets www.cell.com/cell-metabol...

Postdoctoral Researcher

📣 Exciting opportunity!

The McEwen Stem Cell Institute at @uhnresearch.ca is hiring a Postdoc Researcher to join the Protze Lab. The project focuses on #HumanPluripotent stem cell-derived AVNLPCs and their application as a biological conduction bridge.

🔗 jobs.smartrecruiters.com/UniversityHe...

We are launching a new initiative to support experimental design, data management/analysis and bioinformatics. Early days yet, but check it out here.

www.bcell.org/adi-datasci....

Come join us in Vancouver! Exciting opportunity for a more senior investigator researching new regenerative medicine approaches for Type 1 diabetes. $8M in funding for successful candidate research.ubc.ca/media/file/j...

Very excited about our project aiming at advancing cell therapies for type 1 diabetes. and very thankful for receiving funding from @stemcellnetwork.ca

Glucose metabolism and regulation in establishing human stem cell-derived β cell maturation Efforts to generate mature stem cell-derived β (SC-β) cells have been ongoing for decades, yet their functional performance still falls short of prima…

Review on metabolism in stem cell derived beta cells from former PhD student with us, Frank Lin. Cell Reports @cp-cellreports.bsky.social

www.sciencedirect.com/science/arti...

Congratulations!

Lim Lab Exploring how 14-3-3 proteins contribute to metabolism and metabolic diseases

There is still a spot for a PhD student or Postdoc in the Lim Lab! If you are interested in metabolism, 14-3-3 proteins, adipocytes, or beta-cells, please email me (details at www.limlab.ca). International applicants are welcome!

Positions are fully funded. Looking forward to working with you!

Congrats to @sarahcolpitts.bsky.social and the @sarahcrome.bsky.social lab! Check out the effects of ILC-islet co-tx below 👇👇

Neat discussion below! 👇👇

Human iPSC–derived nephron progenitor cells treat acute kidney injury and chronic kidney disease in mouse models Expanded human iPSC–derived nephron progenitor cells secrete renoprotective factors that have therapeutic potential for AKI and CKD.

📣 NEW PAPER ALERT! 🧵
I love kidney organoids - tiny nephron clusters grown in the lab from pluripotent stem cells. But can they treat kidney disease? New data suggests they can (in mice)!
Let's dive in ⬇️
tinyurl.com/mr3sd6vu
#KidneyOrganoids #CellTherapy #ChronicKidneyDisease #AcuteKidneyInjury

Could a pill cure diabetes? A U of A researcher is working on it A simple pill to treat or even cure diabetes could be possible, thanks to University of Alberta research — and funding that is laying vital groundwork.

Excited to enroll our first participant for testing an agent (tolimidone) we hope will promote beta cell regeneration, building on preclinical work from Dr Jean Buteau at @albertadiabetes.bsky.social. Supported by Alberta Diabetes Foundation & biodexa pharmaceuticals www.ualberta.ca/en/folio/202...

Is ELISA success correlated with strength with which plate is banged when washing?

NPAS4 depletion in POMC neurons protects from obesity and alters the feeding-regulated transcriptome in male mice Abstract. Immediate Early Genes (IEGs), such as Neuronal PAS domain protein 4 (Npas4), are induced as part of the response to environmental stimuli. In the

Thrilled to share our latest work, which was the outstanding doctoral work of @samanthajsyoon.bsky.social academic.oup.com/endo/advance... 1/12

New data from Gary Lewis and colleagues @uhnresearch.bsky.social interrogating how GLP-2 modulates chylomicron secretion in rats via VEGFR3 and MLC2 www.ghadvances.org/article/S277...

Congratulations!

NIH cancels funding for landmark diabetes study at a time of focus on chronic disease The Trump administration has canceled funding for an ongoing 30-year, nationwide study tracking patients with prediabetes and diabetes, researchers said.

@elaineywchen.bsky.social www.statnews.com/2025/03/17/t...

Assistant / Associate Professor (Tenure Track), Department of Pharmacology and Therapeutics - Montréal, Quebec (CA) job with McGill University | 12837963 Faculty of Medicine and Health Sciences – Department of Pharmacology and Therapeutics, Toxicology (L000054

Tenure track position in pharmacology or toxicology at McGill, in Montreal!!!

www.nature.com/naturecareer...

Come and work with us at the Alberta Diabetes Institute. We are connecting people with T1D and researchers to accelerate innovation to improve the lives of people with diabetes. We need a project lead to help us. apps.ualberta.ca/careers/post...