Troels Kjeldsen

Our feasibility study on heavy slow resistance training combined with patient education in adults with gluteal tendinopathy was discussed in a recent episode of the podcast "PT Inquest".
Spotify: open.spotify.com/episode/0xDK...
Full paper here: www.sciencedirect.com/science/arti...

Oxford Knee Score over time

NEW RESEARCH—Assessing clinical and cost effectiveness of total versus partial knee replacement (TOPKAT): 10-year follow-up of a multicentre, randomised controlled trial bit.ly/4pAMZMq #Medsky #Rheumsky #Orthosky

🏋️‍♂️Our study showed feasibility of a 12-week program combining heavy slow resistance training with patient education in gluteal tendinopathy.
doi.org/10.1016/j.ms...
✅ The intervention was safe and feasible, showing promising results that warrant investigation in a RCT.

Booster sessions for maintaining the effect of neuromuscular exercise and progressive resistance training in hip osteoarthritis: 12-month follow-up from a multicenter cluster-randomized controlled tri... Clinicaltrials.gov (NCT04714047).

Link to paper published in
@oacjournal.bsky.social here: pubmed.ncbi.nlm.nih.gov/40712915/

Just returned from Fukuoka Japan attending the #ISHA2025 Scientific Meeting with great colleagues.
I presented results from the Hip Booster trial, showing that exercise booster sessions are not effective for maintaining effects of exercise in hip OA.

@stskou.bsky.social @progrez.bsky.social @au.dk @aarhusuniint.bsky.social

Exercise generally does not increase the breakdown of joints affected by osteoarthritis. However, this has not yet been studied specifically in hip osteoarthritis. Read more – and if you have hip osteoarthritis, you may participate in a scientific study:
videnskab.dk/krop-sundhed...

@au.dk @progrez.bsky.social

Clinical and cost-effectiveness of a cycling and education intervention versus usual physiotherapy care for the treatment of hip osteoarthritis in the UK (CLEAT): a pragmatic, randomised, controlled t... The CHAIN intervention showed superior outcomes compared with usual physiotherapy care, and the feasibility of delivering a low-cost, community-based intervention within the NHS was shown. However, lo...

Also wrote a comment in @thelancetrheum.bsky.social
on another RCT, showing that stationary biking and education is effective in hip osteoarthritis:
RCT: thelancet.com/journals/lan...
Comment: www.thelancet.com/journals/lan...

Just published findings in @oacjournal.bsky.social from 1 year follow-up of the Hipbooster RCT, showing that in hip osteoarthritis, 4 additional group exercise sessions were ineffective for improving long-term effects of an initial 3-month intervention.
Paper: pubmed.ncbi.nlm.nih.gov/40712915/

Group-based cycling and education for hip #osteoarthritis

Linked Comment by @tkjeldsen.bsky.social & Inger Mechlenburg bit.ly/4mqEJgH #Medsky #Rheumsky #Physiosky

NEW RESEARCH—Clinical and cost-effectiveness of a cycling and education intervention versus usual physiotherapy care for the treatment of hip #osteoarthritis in the UK (CLEAT): a pragmatic, randomised, controlled trial bit.ly/4mm0iia #Medsky #Rheumsky #Physiosky

@au.dk

Thrilled about engagement at our symposium #ExerciseasMedicine at Aarhus University last week. The overall take-away message for me is how exercise impacts trajectories for healthy ageing and for those who live with disease. There are still challenges, one being how to ensure long-term engagement.

Still spots left on the 5th of March for an exciting afternoon at Aarhus University exploring Exercise as Medicine for healthy ageing and disease prevention. Register here (free of charge):
lnkd.in/d6GkEw2t

Accumulating evidence suggests that nonsurgical management can play a role before surgery is considered.

Such a strategy carries fewer risks for adverse events and lowers cost without compromising outcomes.

www.acpjournals.org/doi/10.7326/...

@thelancetrheum.bsky.social @au.dk

Addressing evidence gaps in exercise for hip osteoarthritis Although several clinical trials have been conducted to explore the benefits of exercise therapy for hip osteoarthritis, major evidence gaps persist in this area, potentially compromising the clinical...

I got lucky and was invited to write a comment for The Lancet Rheumatology: www.thelancet.com/journals/lan...
We discuss evidence gaps in hip OA, propose new avenues for study, and suggest that exercise is still a suitable first-line treatment. Happy to get your 2 cents on these issues.

Join us 5th of March for an exciting afternoon exploring Exercise as Medicine for healthy ageing and disease prevention. Register here (free of charge): events.au.dk/exerciseasme...
The symposium is hosted by Aarhus University and Aarhus University Hospital.

@au.dk @aarhusuniint.bsky.social

Join us 5th of March for an exciting afternoon exploring Exercise as Medicine for healthy ageing and disease prevention. Register here (free of charge): events.au.dk/exerciseasme...
The symposium is hosted by Aarhus University and Aarhus University Hospital.

@au.dk @aarhusuniint.bsky.social

I would like to be added as well, please :)

BERNIE SANDERS: Vaccines do not cause autism. Do you agree?

RFK Jr: As I said, I'm not going into HHS with any preordained--

SANDERS: I asked you a simple question, Bobby

RFK Jr: If you show me those studies ...

SANDERS: That is a very troubling response

Publish or Perish: A Hilarious Card Game Based on Academia I had the opportunity to play an advanced copy of “Publish or Perish,” a new card game that satirizes the world of academia. Created by Max Bai, this game offers a funny take on the oft…

"Publish or Perish" is now a card game, which should be especially great for lab parties!
economistwritingeveryday.com/2024/08/10/p...

🧪🌊⚒️ #academicsky

Exercise as medicine in Parkinson’s disease Parkinson’s disease (PD) is an incurable and progressive neurological disorder leading to deleterious motor and non-motor consequences. Presently, no pharmacological agents can prevent PD evolution or...

Exercise is medicine in neurodegenerative populations
(or perhaps more than / different from medicine)

Have a read on our previous work on this topic 👇

jnnp.bmj.com/content/95/1...

link.springer.com/article/10.1...

@progrez.bsky.social

If you have been diagnosed with hip osteoarthritis and live in Denmark, you may be eligible to participate in our trial on education and exercise:
clin.au.dk/orthoresearc...

Giant study finds untrustworthy trials pollute gold-standard medical reviews Two-year collaboration aims to create tools to help counter the tide of flawed research.

Fake or flawed studies are polluting systematic reviews in medicine and other fields - but how do you spot them?
For Nature, I report on efforts to create a short checklist of red flags, and on the automated integrity tools emerging to help.
www.nature.com/articles/d41...

Controversial COVID study that promoted unproven treatment retracted after four-year saga Paper on hydroxychloroquine led by French researcher Didier Raoult is second-most-cited study ever to be withdrawn.

It only took 4 years, but the garbage study that initially claimed hydroxychloroquine could treat COVID19 has been retracted. As with Wakefield’s fraudulent paper falsely tying vaccines to autism, the damage has already been done. It was cited more than 3600 times. www.nature.com/articles/d41...

Associations between changes in leg extensor muscle power and physical function after supervised exercise in patients with hip osteoarthritis. Secondary analysis from the hip booster trial To investigate associations between changes in leg extensor muscle power of the affected limb (ΔLEP) and changes in physical function after 12 weeks o…

We found that changes in all 5 measures of physical function were associated with changes in muscle power after supervised exercise in people with hip osteoarthritis.

Objective measures were more closely related to muscle power than subjective ones.

sciencedirect.com/science/arti...

As Bluesky seems to have exploded over the weekend, I am reposting this ⬇️

Starter Pack for #sports & #exercise: a (very incomplete but evolving) list of researchers, labs & resources that cover physical activity, sports & exercise 🦵💪

Just DM me, if you would like to be added 🙂

go.bsky.app/4hjz2Q6