Grampospath

Mortality Among Patients With Invasive Group A Streptococcal Infections Caused by the M1UK Lineage: A Retrospective Cohort Study in England and Wales Emm1 invasive Strep A incurs a high case fatality rate. In this national cohort, 24.4% of those with M1UK iGAS died, though this was not different from anc

The #StrepA upsurge of 2022/23 was dominated by emm1; the high mortality associated with emm1 is alarming.
What is more alarming is that those who die, sadly die quickly esp children ; blaming any single person for a strep A death is not sensible.

academic.oup.com/cid/advance-...

Excited to share our first look at Enterococcus faecium infection biology: diabetic wounds are complex, and E. faecium persists despite early immune responses. In diabetic mice, it shows impaired clearance + sustained neutrophil recruitment, worsening healing.

Coming to this a bit late but many congratulations 🎉!Sad can’t order for Christmas-would have bought more!! But looking forward to seeing it

Definitely worth a read and raises all sorts of questions about how quickly we become vulnerable as a population if we aren’t immune/immunised.👇

@imperialmed.bsky.social @imperialinfect.bsky.social @imperialbrc.bsky.social

ACFs in Infectious Diseases in London are now advertised including at Imperial /LSHTM /City St Georges /Kings. Open evening October 2nd about all our NIHR ACF/ACL programmes -details👇

Investigating pathogenicity in zoonotic Streptococcus suis at University of Cambridge on FindAPhD.com PhD Project - Investigating pathogenicity in zoonotic Streptococcus suis at University of Cambridge, listed on FindAPhD.com

www.findaphd.com/phds/project...

Excellent work !!!

🧵 Our paper out today in @naturemedicine.bsky.social

www.nature.com/articles/s41...

On development of #StrepA #Immunity over life course in #TheGambia raising hope for #vaccines on the horizon

1/

#Immunosky #IDsky #MicroSky #globalhealth.

Is that a streptocarpus in a streptocorcus office by any chance?! 🤨

Congratulations to Tom Parks the new President of the Lancefield Society and Committee members ! #LISSSD2025 @ispylifenetwork.bsky.social

Evening kick off off at #Lancefield #LISSSD2025 in Brisbane for all #Strep enthusiasts @ispylifenetwork.bsky.social @ispyexplore.bsky.social

Academy Fellow Professor Chris Chiu next to a quote that reads: "The challenge of my research can only be addressed by promoting innovative and collaborative research, a central aspect of the Academy’s mission."

Congratulations to Prof @chrischiulab.bsky.social who has been elected as a new Fellow to the Academy 🎉

Prof Chiu is studying protective immunity in human respiratory viral infections. With an urgent need for improved vaccines, this is a critical area of work 💉

👉 Read more: ow.ly/6ehl50VXSlc

Points to a specific but I think meaningful immunity gap against two of the pathogens tested - strep A and RSV in 3-4 y olds. Age specific increment in anti Strep antibodies as you might hope. Just less in those post 2020. Preprint of interest to many of us in @ispylifenetwork.bsky.social

Pleased to share @chemo_king’s paper explaining why spycep does what it does !
www.sciencedirect.com/science/arti...

Colander pinhole camera projecting eclipse onto pavement

Science engagement in the streets of north London on a (finally!!) sunny day.

The actual list is here -the bbc list isn’t quite right www.gov.uk/government/p...

Vacatures - PhD (x2) in Staphylococcus aureus immune interaction - Amsterdam UMC Do you have ambition to be trained in broad, top-class scientific and professional skills and gain experience in industry and academia? Apply now!

🔔🔔 🔔 Sound the alarm! Not 1 but 2 PhD positions available in my research group at Amsterdam UMC studying the interaction between S. aureus wall teichoic acids and the host immune system. Multidisciplinary projects with experience in academia and industry. werkenbij.amsterdamumc.org/en/vacatures...

Superheroes!!

AI mirrors experimental science to uncover a novel mechanism of gene transfer crucial to bacterial evolution AI models have been proposed for hypothesis generation, but testing their ability to drive high-impact research is challenging, since an AI-generated hypothesis can take decades to validate. Here, we ...

With @jrpenades.bsky.social, we challenged Google AI co-scientist to generate hypotheses. In just 2 days, it recapitulated our unpublished, experimentally confirmed mechanism for how cf-PICIs spread between bacterial species! @imperialcollegeldn.bsky.social
tinyurl.com/3byyaeh2

😳 what will be next… ?

Description Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

📣Research Technician job alert! Needed to support our #iSpyLIFE field work and #strep biobanking. www.imperial.ac.uk/jobs/search-...

A very happy and Gram positive Christmas to everyone! 🎄🎄🎄

Congratulations -good to see this out !!