Somatic mutations can drive disease, but hard to distinguish from technical error. Rhys Gillman introduces SCARCE: Single-Cell Analysis of Rare Clonal Events which blends scDNA seq with surface markers to find clonal variants in specific cell types www.biorxiv.org/content/10.1101/2025.10.30.685685v1
16.02.2026 02:06 β
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Expanded T cell clones with lymphoma driver somatic mutations accumulate in refractory celiac disease
Dysregulated T cells and progenitors with lymphoma driver mutations are enriched in duodenal biopsies from patients with refractory celiac disease.
New paper from the Goodnow lab showing how refractory celiac disease (no response to GF diet) often driven by the accumulation of somatic mutations in expanded T-cell populations in the gut.
@garvaninstitute.bsky.social @andrewcalcino.bsky.social
www.science.org/doi/10.1126/...
16.05.2025 01:25 β
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Postdoctoral Research Fellow, Bioinformatics - Cairns, QLD, Australia
James Cook University (JCU) is creating a brighter future for life in the Tropics and beyond, through education and research that makes a difference locally and globally.Β
We now have an opportunity a...
An opportunity exists for an exceptional early career bioinformatician to join the Field lab in tropical Cairns Australia, home of the Great Barrier Reef. Job offered until Dec 2026 however extension possible. Internationals welcome to apply. Closes Mar 26th!
careers.jcu.edu.au/jobs/postdoc...
26.02.2025 01:59 β
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Harnessing genomic technologies for one health solutions in the tropics - Globalization and Health
Background The targeted application of cutting-edge high-throughput molecular data technologies provides an enormous opportunity to address key health, economic and environmental issues in the tropics...
π Genomic Technologies for #OneHealth Solutions in the Tropics tinyurl.com/bdnfye2y
π The tropics: home to 50% of the worldβs population and 80% of it's biodiversity face unique challenges.
#SustainableFuture #Biodiversity
@andrewcalcino.bsky.social @iracooke.bsky.social @mattfield100.bsky.social
08.12.2024 23:59 β
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