@challis-group.bsky.social
Group of scientists at the University of Warwick and Monash University interested in the discovery, biosynthesis, bioengineering, mechanism of action, and translational application of microbial natural products and the enzymes that assemble them
Check out the latest version of our preprint on nitrogen deletion in HDAC-targetting anticancer drug biosynthesis. Amazing work by Xinyun Jian @monashuniversity.bsky.social, Jinlian Zhao @uni-of-warwick.bsky.social and colleagues in the Cryle and Fairlie labs.
www.biorxiv.org/content/10.1...
Lona Alkhalaf will speak about the discovery, structure, and mechanism of a cool new family of enzymes discovered by the group at the 29th Enzyme Mechanisms Conference.
www.enzymemechanismsconference.org/speakers
Greg Challis will be presenting the group's latest insights into peptidyl epoxyketone biosynthesis at the 16th Australian Peptide Conference in beautiful Tasmania.
www.peptides2025.org
Interested in natural product producing microorganisms? 🦠 See you in Berlin... 😀
22.05.2025 13:02 — 👍 12 🔁 8 💬 1 📌 0The names of panel members for the criteria-setting phase of REF 2029 have now been announced on our panels pages. 2029.ref.ac.uk/news/expert-...
04.09.2025 12:12 — 👍 11 🔁 9 💬 0 📌 5
Excited to announce our latest preprint, exploring the stereochemistry & antiviral properties of natural product MM46115 (pellemicin) against influenza. 🦠 💊 Big thanks to all co authors, including @afifahtasnim.bsky.social @craigpthomp.bsky.social and others. www.biorxiv.org/content/10.1...
19.09.2025 12:11 — 👍 14 🔁 9 💬 0 📌 0
