Tanmay Bharat's Avatar

Tanmay Bharat

@tbharat-lab.bsky.social

MRC-LMB #cryoET #biofilms #S-layers #antibiotics https://www2.mrc-lmb.cam.ac.uk/groups/bharat/

1,299 Followers  |  534 Following  |  40 Posts  |  Joined: 17.11.2024
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Posts by Tanmay Bharat (@tbharat-lab.bsky.social)

We are excited to be recruiting a new tenure track group leader in the Structural Studies Division at MRC LMB! It is an amazing place to start your own lab.
@mrclmb.bsky.social

Please get in touch if you have any questions.
www.nature.com/naturecareer...

25.02.2026 22:25 β€” πŸ‘ 50    πŸ” 53    πŸ’¬ 1    πŸ“Œ 0
Job opening for Research Group Leader in Structural Studies at MRC Laboratory of Molecular Biology, focusing on macromolecular structures.

Job opening for Research Group Leader in Structural Studies at MRC Laboratory of Molecular Biology, focusing on macromolecular structures.

Are you a structural biologist pushing the boundaries of molecular science with an ambitious research programme?
Join our Structural Studies Division as a tenure-track Group Leader, with core funding, world-leading facilities & enthusiastic colleagues.
Apply by 16 MAR
www.nature.com/naturecareer...

24.02.2026 09:45 β€” πŸ‘ 36    πŸ” 48    πŸ’¬ 0    πŸ“Œ 2
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Our latest preprint: Together with the team of Jan LΓΆwe, @danieltamarit.bsky.social and many others we discovered and characterized several Asgard tubulin genes and propose that microtubule architecture and dynamics evolved in Asgard archaea prior to eukaryogenesis
www.biorxiv.org/content/10.6...

16.02.2026 16:43 β€” πŸ‘ 134    πŸ” 61    πŸ’¬ 3    πŸ“Œ 4
Research Group Leader Tenure Track - Structural Studies - LMB 2775 - Medical Research Council Location: Cambridge. Vacancy: Research Group Leader Tenure Track - Structural Studies - LMB 2775. Closing Date: 16/03/2026, 23:55

Please spread the word: the Structural Studies Division @mrclmb.bsky.social is looking for a new tenure-track, independent group leader with an exciting plan in any area of Structural (Molecular & Cell) biology, in discovery biology and/or methods development. πŸ₯³

mrc.tal.net/vx/mobile-0/...

16.02.2026 12:09 β€” πŸ‘ 83    πŸ” 102    πŸ’¬ 1    πŸ“Œ 2
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How did life arise from simple chemical building blocks?

New #LMBResearch led by @edogia.bsky.social in @philholliger.bsky.social group has identified a small self-replicating ribozyme that could be the answer.

Read more: mrclmb.ac.uk/news-events/...

13.02.2026 10:20 β€” πŸ‘ 52    πŸ” 31    πŸ’¬ 0    πŸ“Œ 2

congrats Kelly, so well deserved!

10.02.2026 10:58 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Research Group Leader Do you want to lead groundbreaking research in computational biology? Join us at EMBL-EBI! EMBL's European Bioinformatics Institute (EMBL-EBI) is seeking talented and highly-motivated scientists to jo...

We are hiring for group leaders again β€” EBI is a great place to start your research group!

embl.wd103.myworkdayjobs.com/EMBL/job/Hin...

30.01.2026 09:02 β€” πŸ‘ 66    πŸ” 89    πŸ’¬ 0    πŸ“Œ 2
Molecular Biology of Archaea: Life Through the Prism of Archaea In 1977, Woese and colleagues revealed Archaea as a distinct domain of life. Building on this insight, the discovery of Asgard archaea has strengthened the view that many hallmarks of eukaryotic cell…

A reminder to sign up for the 2026 EMBO archaeal meeting im Cambridge: meetings.embo.org/event/26-arc.... Registration is open. We are looking forward to hosting you!

23.01.2026 08:15 β€” πŸ‘ 40    πŸ” 35    πŸ’¬ 0    πŸ“Œ 1
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Sign up now for the EMBO Workshop "#MolecularBiology of #Archaea: Life Through the Prism of Archaea" in Cambridge, UK, 6–10 July 2026.

Deadline: 15 April

https://meetings.embo.org/event/26-archaea
#EMBOArchaeaBiology #EMBOevents #CellBiology #StructuralBiology #ecology #evolution #biophysics πŸ§ͺ

17.12.2025 07:10 β€” πŸ‘ 20    πŸ” 5    πŸ’¬ 0    πŸ“Œ 1

We have an opening for a research support officer. Come and join us! Please share.

22.12.2025 12:09 β€” πŸ‘ 17    πŸ” 22    πŸ’¬ 0    πŸ“Œ 0
Molecular Biology of Archaea: Life Through the Prism of Archaea In 1977, Woese and colleagues revealed Archaea as a distinct domain of life. Building on this insight, the discovery of Asgard archaea has strengthened the view that many hallmarks of eukaryotic cell…

Are you a long-time fan of Archaea, an extremophile-phile, or are you simply curious?

Either way, we have good news.
We’re delighted to announce the 2026 EMBO Workshop on Archaea, 6–10 July.

Sign up: meetings.embo.org/event/26-arc...

We look forward to seeing you in Cambridge, UK.

Please repost!

16.12.2025 12:00 β€” πŸ‘ 78    πŸ” 51    πŸ’¬ 2    πŸ“Œ 1
Postdoctoral Scientist - Neurobiology - Dr Michel Goedert - LMB 2752 - Medical Research Council Location: Cambridge. Vacancy: Postdoctoral Scientist - Neurobiology - Dr Michel Goedert - LMB 2752. Closing Date: 04/01/2026, 23:55

Postdoc opportunity with Michel Goedert and myself to work on #cryoEM/#cryoET structures of #amyloids. Feel free to email me with any questions you might have.

mrc.tal.net/vx/mobile-0/...

10.12.2025 14:28 β€” πŸ‘ 21    πŸ” 23    πŸ’¬ 1    πŸ“Œ 0
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Top UK scientist says research visa restrictions endanger economy Prof Sir Paul Nurse says the UK is "shooting itself in the foot" with its visa system for researchers.

BBC News - Top UK scientist says research visa restrictions endanger economy
www.bbc.com/news/article...

05.12.2025 06:35 β€” πŸ‘ 33    πŸ” 22    πŸ’¬ 0    πŸ“Œ 2
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Anthony A. Hyman will become EMBL’s next Director General.

He joins EMBL from @mpi-cbg.de in Dresden. He is also Professor of Molecular Biology @tudresden.bsky.social, and was a group leader at EMBL Heidelberg from 1993 to 1999.

www.embl.org/news/people-...

27.11.2025 13:02 β€” πŸ‘ 253    πŸ” 67    πŸ’¬ 11    πŸ“Œ 11
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Apply now to attend the next EMBO Bacterial Networks meeting #EMBOBacNet

πŸ—“οΈ13-18 September 2026
πŸ“Sant Feliu de Guixols, Spain

πŸ“Program and registration info: meetings.embo.org/event/26-bac...

πŸ‘©β€πŸ”¬Organised with co-chair @s-lab.bsky.social and ECR @coralietesseur.bsky.social

#MicroSky

20.11.2025 10:16 β€” πŸ‘ 41    πŸ” 26    πŸ’¬ 1    πŸ“Œ 0
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Deaths linked to antibiotic-resistant superbugs rose 17% in England in 2024 Data also shows an average of nearly 400 newly reported cases of antibiotic-resistant infections a week last year

β€˜The latest surveillance data found that the number of antibiotic-resistant infections in 2024 equated to an average of nearly 400 newly reported cases a week.’
www.theguardian.com/society/2025...

13.11.2025 23:27 β€” πŸ‘ 18    πŸ” 12    πŸ’¬ 0    πŸ“Œ 1

Pleased to share our review on S-layers with @bupbuse.bsky.social, Andriko von KΓΌgelgen, and @tbharat-lab.bsky.social, where we explore recent advances and argue that deeper insight into S-layers is key to deciphering microbial interactions and community organization. @mpi-bio-fml.bsky.social

13.11.2025 21:16 β€” πŸ‘ 15    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0
Introduction to microbial surface layers (S-layers)
YouTube video by MRC Laboratory of Molecular Biology Introduction to microbial surface layers (S-layers)

Also see the associated primer video on S-layers made by the @mrclmb.bsky.social Visual Aids department Konstantinos Alexandrou and Shraddha Nayak!

www.youtube.com/watch?v=fgSf...

13.11.2025 20:13 β€” πŸ‘ 9    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
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Assembly, architecture and functional roles of microbial surface layers - Nature Reviews Microbiology Surface layers (S-layers) are ubiquitous protein assemblies that coat prokaryotic cells, with their functional roles increasingly coming into focus. In this Review, Isbilir and colleagues discuss rece...

Assembly, architecture and functional roles of microbial surface layers

Review article published in @natrevmicro.nature.com with @bupbuse.bsky.social, Andriko von KΓΌgelgen and @vikramalva.bsky.social.

S-layers are everywhere!

www.nature.com/articles/s41...

13.11.2025 20:13 β€” πŸ‘ 87    πŸ” 32    πŸ’¬ 3    πŸ“Œ 6

Grows quite slowly over months, maybe that’s why? Lots to study and much to learn…

10.11.2025 14:57 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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An Asgard archaeon with internal membrane compartments

Brilliant study led by @fmacleod.bsky.social and Andriko von KΓΌgelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!

www.biorxiv.org/content/10.1...

07.11.2025 10:44 β€” πŸ‘ 387    πŸ” 169    πŸ’¬ 10    πŸ“Œ 22

It’s 3-fold…

02.11.2025 16:07 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Be our neighbour, please apply!

29.10.2025 18:29 β€” πŸ‘ 8    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Cool!

15.10.2025 11:14 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com

15.10.2025 06:33 β€” πŸ‘ 464    πŸ” 146    πŸ’¬ 17    πŸ“Œ 39

We have an open post-doc position in my group to study mRNA cleavage and polyadenylation using biochemical reconstitution and cryoEM.

Please get in touch if you are interested in joining this amazing team! πŸ”¬πŸ§¬πŸ€©
#RNA #cryoEM

27.09.2025 11:06 β€” πŸ‘ 59    πŸ” 52    πŸ’¬ 0    πŸ“Œ 1

It's deep when the GPU starts making a loud noise

16.09.2025 17:51 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

The final version of our multispectral microscopy manuscript is now online at Nature Photonics: www.nature.com/articles/s41...

The main additions are some further comparisons to yet more unmixing algorithms, in which we find that our algorithm is still the most accurate.

16.09.2025 07:43 β€” πŸ‘ 35    πŸ” 16    πŸ’¬ 1    πŸ“Œ 0
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Excited about our most recent collaboration with the Wong lab, lead by William Schmidt, describing a T4P and CdrA-mediated mechanism of sensing surface EPS. Fun stuff and great work William and team.
www.nature.com/articles/s41...

05.09.2025 12:21 β€” πŸ‘ 24    πŸ” 9    πŸ’¬ 1    πŸ“Œ 0
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Sub-cellular chemical mapping in bacteria using correlated cryogenic electron and mass spectrometry imaging

Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social

www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social

31.08.2025 18:44 β€” πŸ‘ 142    πŸ” 62    πŸ’¬ 3    πŸ“Œ 4