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Christian Webb, PhD

@christianwebb.bsky.social

Associate Professor | Harvard Medical School Co-Director | Center for Depression, Anxiety, & Stress Research Director | Treatment & Etiology of Depression in Youth Lab | McLean Hospital | www.WebbsLab.com McGill & UPenn alum | Canadian in Boston

2,368 Followers  |  741 Following  |  108 Posts  |  Joined: 21.09.2023  |  2.5374

Latest posts by christianwebb.bsky.social on Bluesky

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Join us at the Technology in Psychiatry Summit (TIPS) #TIPS2025! Dec 11โ€“12 | Virtual | 11 AMโ€“5 PM ET

๐Ÿ’ก Topics:
โ€ข AI-driven mental health apps
โ€ข LLMs in dementia caregiving
โ€ข Digital Navigators bridging tech + care
โ€ข AI for eating-disorder treatment
...& much more

๐Ÿ”— tips.societyconference.com/v2/

07.11.2025 21:23 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Check out this write-up of a recent DPN article from @bbrfoundation.bsky.social highlighting BBRF awardees @christianwebb.bsky.social, @erika-forbes.bsky.social, and @diegopizzagalli.bsky.social. Congrats!

bbrfoundation.org/content/smar...

27.10.2025 14:13 โ€” ๐Ÿ‘ 4    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Smartphone Sensors + ChatGPT Successfully Tracked & Predicted Symptoms in Adolescents with Anhedonia | Brain & Behavior Research Foundation The ubiquity of smartphones and the rapid advance and widespread public adoption of โ€œAIโ€ tools like ChatGPT (especially among the young) have raised hopes among some researchers that such technologies...

Thanks to @bbrfoundation.bsky.social for highlighting our lab's study (led by @hadarfisher.bsky.social & @nigeljaffe.bsky.social) using๐Ÿ“ฑsmartphone sensors + LLM-derived text ratings to track behavioral activation and symptom change in teens with anhedonia.
bbrfoundation.org/content/smar...

24.10.2025 20:11 โ€” ๐Ÿ‘ 11    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿ“ข New large study of ~1.5 million patients in NHS Talking Therapies finds that teens/young adults (ages 16-24) had 17-26% *lower* odds of reliably improving vs 25-65 year-olds. Time to rethink youth-centred mental-health delivery?
๐Ÿ”— tinyurl.com/532y6v67

22.10.2025 14:07 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Great work Hadar!

17.10.2025 21:08 โ€” ๐Ÿ‘ 6    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Now out in NPP โ€“ Digital Psychiatry and Neuroscience! ๐Ÿ“ฑ๐Ÿง 

Can LLMs and smartphone sensing help us track therapy progress in real time?

17.10.2025 21:07 โ€” ๐Ÿ‘ 8    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
Client Challenge

๐Ÿ†• study by @hadarfisher.bsky.social @nigeljaffe.bsky.social @diegopizzagalli.bsky.social @christianwebb.bsky.social tested whether smartphone mobility sensing & LLM ratings of text can track behavioral activation in teens to boost engagement in rewarding activities

www.nature.com/articles/s44...

14.10.2025 14:45 โ€” ๐Ÿ‘ 8    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
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Grateful to @willemkuyken.bsky.social for being such a gracious host and insightful guide at Oxford โ€” and to Jamie Delgadillo for the same at Kingโ€™s College London. Inspiring conversations, wonderful campuses, and a fantastic trip all around. ๐Ÿ‡ฌ๐Ÿ‡ง๐ŸŽ“

12.10.2025 10:12 โ€” ๐Ÿ‘ 8    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Balfour Mount, who revolutionized end-of-life care, died at palliative unit named in his honour | CBC News Mount devoted his life to caring for others and alleviating suffering. In interviews, his family and colleagues remembered him as both deeply compassionate and as a fierce advocate for the humanity of...

"Dr. Balfour Mount, who coined the term 'palliative care' and whose profound empathy helped revolutionize health-care in North America, died peacefully on Sept. 25 at the palliative care unit that bears his name." www.cbc.ca/news/canada/...

07.10.2025 17:33 โ€” ๐Ÿ‘ 105    ๐Ÿ” 29    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 3

@mcleanhospital.bsky.social Technology in Psychiatry Summit #TIPS returns this year Dec 11-12. We have exciting keynotes lined up, including Drs. Pattie Maes (MIT Media Lab), Isaac Galatzer-Levy (Google DeepMind), and Derrick Hull (Slingshot AI). Submissions are now open. See below for info.

16.09.2025 13:48 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

collab w/ the wonderful @sgoldbergphd.bsky.social @lorihilt.bsky.social @hadarfisher.bsky.social @carolineswords.bsky.social and Dan Bolt

12.09.2025 20:34 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Conventional self-report and EMA measures of rumination provide distinct and clinically meaningful information. When deciding to use EMA in intervention studies, researchers should carefully consider the psychometric properties of their measures and the precise construct they intend to capture

12.09.2025 20:31 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

We found larger changes in rumination for the conventional self-report measures relative to EMA. Notably, change in both self-report and EMA rumination accounted for unique variance in overall depressive symptom improvement, demonstrating incremental predictive validity. 5/n

12.09.2025 20:31 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Conventional self-report and EMA rumination were only modestly correlated, particularly w/ regards to change over time, which may be due to the lower reliability of change scores and that they tap different โ€œselvesโ€ (e.g., experiencing vs. remembering self) 4/n

12.09.2025 20:30 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

While the reliability of both conventional self-report rumination (at baseline and post-intervention) and mean EMA rumination scores were high, we found a substantial decline in reliability when assessing change over time, especially for EMA. 3/n

12.09.2025 20:28 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

We analyzed data from 4 app-based meditation trials (N=412) to assess the reliability, validity, and sensitivity to change of conventional retrospective self-report vs. EMA measures of improvement in rumination. 2/n

12.09.2025 20:27 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Ecological Momentary Assessment as a Measure of Intervention Change: Evaluation in 4 Digital Mental Health Trials Background: Ecological momentary assessment (EMA) is increasingly being incorporated into intervention studies to acquire a more fine-grained and ecologically valid assessment of change. The added uti...

๐Ÿ“ฑEMA is increasingly used in intervention studies to acquire a more fine-grained and ecologically valid assessment of change. But EMA is relatively burdensome. What's the added value? We tried to address this question in our new paper now out @jmirpub.bsky.social www.jmir.org/2025/1/e69297 1/n

12.09.2025 20:26 โ€” ๐Ÿ‘ 43    ๐Ÿ” 14    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Technology in Psychiatry Summit | Supporting Mental Health in the Digital Age

There is still time to submit your symposium, workshop, or poster for the 2025 Technology in Psychiatry Summit (TIPS). Submission deadline is Oct 9. TIPS is taking place virtually as a 2-day meeting Dec 11th and 12th, 2025. #TIPS #technologyinpsychiatry

Link: techinpsych.org

12.09.2025 00:23 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Thanks, Charly. in general it was teens with lower levels of symptoms (e.g., fewer emotional difficulties (SDQ), lower depressive symptoms (CESD), and less executive function difficulties (BRIEF)). Details in the paper

24.08.2025 12:39 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
OSF

Preprint now available here: osf.io/preprints/ps...

24.08.2025 12:35 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿšจ New research alert

We applied machine learning to the large MYRIAD trial (84 schools and 8,376 UK teens) to ask:

๐Ÿ‘‰ Which adolescents benefit most from mindfulness delivered in schools?

Bottom line: One-size-fits-all doesnโ€™t work.

Paper link: tinyurl.com/vvpvfunh

1/n

22.08.2025 20:11 โ€” ๐Ÿ‘ 17    ๐Ÿ” 8    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Coauthors @willemkuyken.bsky.social @hinzeverena.bsky.social and bluesky-less Drs. Ren, Dalgeish, Ford, Greenberg, and Montero-Marin (hope not missing any bluesky accounts)

22.08.2025 20:16 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Focusing only on individual-level interventions risks overlooking broader influences. Future precision prevention should integrate multilevel dataโ€”capturing both individual and contextual drivers of outcomes.
6/n

22.08.2025 20:14 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Youth mental health โ‰  just individual factors.
School climate, poverty & inequities matter too.
Prevention must move beyond one-size-fits-all to integrate both personal + systemic influences.
5/n

22.08.2025 20:14 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Machine learning can identify which adolescents are more likely to benefit from SBMT vs. TAU.

This may point to a path toward precision prevention in schools. Next step: prospective trials testing whether algorithm-guided intervention assignment improves outcomes. 4/n

22.08.2025 20:13 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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We used ML on baseline student + school characteristics to predict change in depression in SBMT vs. TAU.

Results:
โ€ข 19% of students fared better with SBMT (d = 0.22)
โ€ข 37% fared better with TAU (d = 0.22)
โ€ข Compared to negligible average between-group effects in the trial (d = 0.03)
3/n

22.08.2025 20:13 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Are We Talking Too Much About Mental Health? (Published 2024)

The MYRIAD trial compared school-based mindfulness training (SBMT) vs. teaching as usual (TAU) in > 8,000 teens in 84 UK schools. SBMT did *not* outperform TAU in the overall trial. Background via NYT: www.nytimes.com/2024/05/06/h... 2/n

22.08.2025 20:12 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

๐Ÿšจ New research alert

We applied machine learning to the large MYRIAD trial (84 schools and 8,376 UK teens) to ask:

๐Ÿ‘‰ Which adolescents benefit most from mindfulness delivered in schools?

Bottom line: One-size-fits-all doesnโ€™t work.

Paper link: tinyurl.com/vvpvfunh

1/n

22.08.2025 20:11 โ€” ๐Ÿ‘ 17    ๐Ÿ” 8    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Postdoctoral Research Scholar, The Cognition, Affect, and Temperament Lab, College of the Liberal Arts, Department of Psychology-2 APPLICATION INSTRUCTIONS: CURRENT PENN STATE EMPLOYEE (faculty, staff, technical service, or student), please login to Workday to complete the internal application process. Please do not apply here, a...

My lab has an open post-doc position!

We will begin reviewing applications as they come in.

The post-doc will work with a vibrant research team at Penn State in the Department of Psychology and the Child Study Center.

psu.wd1.myworkdayjobs.com/PSU_Academic...

1/3

22.08.2025 20:06 โ€” ๐Ÿ‘ 48    ๐Ÿ” 45    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 3
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Large Language Models are Advanced Anonymizers Recent privacy research on large language models (LLMs) has shown that they achieve near-human-level performance at inferring personal data from online texts. With ever-increasing model capabilities, ...

Does your uni have any firewalled LLMs (contained in your institution and doesn't share data with the web/AI companies). Maybe some LLM solution like arxiv.org/abs/2402.13846
Hadar may have more ideas (she's traveling). Julian Rubel or Justin Baker may have thoughts too. Happy to reach out to them

19.08.2025 16:29 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

@christianwebb is following 20 prominent accounts