Lindsey Kennedy

We are still accepting applications for Principal Investigator positions in:

🔬Biomedical Discovery Research
➡️ apply.interfolio.com/172703

🧬 Population Health Data Science
➡️ apply.interfolio.com/172529

Join our vibrant scientific community in the ❤️ of Toronto!

🗓️ Apply by October 20, 2025.

Whistle-Blower Complaints Detail Tension Over Vaccines at N.I.H.

Last respiratory virus season 278 children in the US died of influenza, more than any year since 2009.

The majority were previously healthy, but 90% had *not* received a flu vaccine.

Facts are stubborn things

www.nytimes.com/2025/09/04/h...

Opinion | Robert F. Kennedy Jr., the CDC and Me I was fired after 29 days because I held the line and insisted on rigorous scientific review.

"Once trusted experts are removed and advisory bodies are stacked, the results are predetermined. That isn’t reform. It is sabotage."

Susan Monarez WSJ op-ed www.wsj.com/opinion/robe...

"The agency then added layers of political review to the grant-making process that would rule out any research at odds with Mr. Kennedy’s “scientifically unsupported position that vaccines caused harm, including autism in children,” the complaints say. Even as it cut some vaccine research, the complaints said, the health department awarded $500 million in May to a universal vaccine project that many scientists said relied on badly outdated technology. "

NIH whistleblowers say HHS manipulated the grant review process to undermine vaccines. @nytimes.com www.nytimes.com/2025/09/04/h...

Me with my recent writing

Deriving Human Intestinal Organoids with Functional Tissue-Resident Macrophages All From Pluripotent Stem Cells Organs of the gastrointestinal tract contain tissue-resident immune cells that function during tissue development, homeostasis, and disease. However, most published human organoid model systems lack r...

Circling back to this paper in CMGH from earlier this year on the generation & functionality of human intestinal organoids

Very timely read for #GIsky as the NIH & FDA are prioritizing new approach methodologies (NAMs) like this

www.cmghjournal.org/article/S235...

Incredibly upsetting and infuriating

Our biomedical enterprise is being absolutely tanked by this administration

Important info for researchers and grant writers:

New statement from the NIH Director discussing the priorities of the agency - these are unsurprising considering the news from the past few months

www.nih.gov/about-nih/ni...

Did I miss a major NIH announcement? I was working on an R01 for a NOSI and just got word it will expire early Sept 2025 when the original expiration date was Sept 2027. I just checked funding opportunities and it looks like most (if not all) active NOSIs are set to expire this fall?

NIH staff ordered to re-evaluate all grants immediately - Research Professional News Research not aligned with new priorities may be terminated, warns agency chief Jay Bhattacharya

New article in Research Professional News

[Sorry about the paywall]

www.researchprofessionalnews.com/rr-news-usa-...

1/6

RFK Jr. Vowed to Find the Environmental Causes of Autism. Then He Shut Down Research Trying to Do Just That. While touting a $50 million initiative to identify the causes of autism, Robert F. Kennedy Jr. is helping lead an administration that is rolling back protections against pollution and toxic chemicals,...

RFK Jr. Vowed to Find the Environmental Causes of Autism. Then He Shut Down Research Trying to Do Just That. Story by @fastlerner.bsky.social www.propublica.org/article/rfk-...

This year the ASH Bridge Grant is funding 25 scientists with $3.75M, 5X more than last year, to keep hematology research moving forward. Congratulations to the recipients! https://bit.ly/3HJ51Ma

#HemeSky #MedSKy #ASHAwards

I’m an award-winning mathematician. Trump just cut my funding. The “Mozart of Math” tried to stay out of politics. Then it came for his research.

I wrote an op-ed on the world-class STEM research ecosystem in the United States, and how this ecosystem is now under attack on multiple fronts by the current administration: newsletter.ofthebrave.org/p/im-an-awar...

Lactate Facilitates Pancreatic Repair Following Acute Pancreatitis by Promoting Reparative Macrophage Polarization During acute pancreatitis (AP), glycolysis is enhanced. The upregulation of glycolysis increases the level of metabolite lactate. Lactate has been shown to facilitate tissue repair across various path...

During acute pancreatitis, the body produces its own protective molecule - lactate💪

An unlikely protector, lactate encourages anti-inflammatory activity to facilitate pancreatic repair🛡️

🧪

www.cmghjournal.org/article/S235...

Opinion | The Playbook Used to ‘Prove’ Vaccines Cause Autism (Gift Article) Data can easily be manipulated to show causation that doesn’t exist.

How to recognize shoddy studies that claim to link vaccines and autism. Essay by @unbiasedscipod.bsky.social Gift link: nyti.ms/3UUNrIp

Former CDC Director William Foege: How public health can fight back in a time of dangerous nonsense “Kennedy would be less hazardous if he decided to do cardiac surgery. Then he would kill people only one at a time,” writes former CDC Director William Foege.

“Kennedy would be less hazardous if he decided to do cardiac surgery. Then he would kill people only one at a time,” writes former CDC Director William Foege.
www.statnews.com/2025/08/18/r...

Screenshot from the linked Aug. 17, 2025 NY Times' opinion piece by Dr. Rick Bright: "The Department of Health and Human Services recently announced it would wind down 22 mRNA vaccine development projects under the Biomedical Advanced Research and Development Authority, or BARDA, halting nearly $500 million in investments. This decision undercuts one of the most significant medical advances in decades, technology that could protect millions more people from the threats ahead. I know the stakes because I was BARDA’s director when the United States made the decision to invest heavily in mRNA. That investment did not begin with Covid-19. It began in 2016, when we faced the Zika virus outbreak. We needed a way to design a vaccine in days, not years, to protect pregnant women and their babies from devastating birth defects. Older vaccine approaches were too slow. The solution was mRNA: a flexible, rapid-response technology that could be reprogrammed for any pathogen once its genetic sequence was known. That early investment laid the groundwork for the lightning-fast Covid-19 response four years later."

By @rickabright.bsky.social, former Director of BARDA...
🛟medsky 🧪 health policy sociology polisky idsky 😷

Dear #LiverSky #HepatoSky researchers:

PSC Partners grant cycle is now open! The deadline for your LOI is December 1, 2025

Need help crafting your grant? I offer editing services to help strengthen your proposal. Let's work together to make your work stand out!

pscpartners.org/research/res...

The Role of the Hexosamine-Sialic Acid Metabolic Pathway Mediated by GFPT1/NANS in c-Myc-Driven Hepatocellular Carcinoma Hepatocellular carcinoma (HCC) frequently involves metabolic reprogramming, which promotes oncogenesis and metastasis. However, the underlying molecular mechanisms remain insufficiently explored. In t...

❓Shifts in cell metabolism drive liver cancer - but what are the mechanisms?

🎯This study found that a pathway (hexosamine biosynthetic pathway) may play a role in liver cancer progression

www.cmghjournal.org/article/S235...

a cartoon character from south park is holding a puppet that says pay attention ALT: a cartoon character from south park is holding a puppet that says pay attention

Today, Bhattacharya sent a document entitled

"NIH Priorities and Internal Review of Intramural and Extramural Programs"

to Institute and Center Directors and other leaders.

I am trying to get a clean copy.

These "Priorities" will likely be "Agency Priorities" for grant funding and termination.

Please sign and share our petition to remove RFK Jr.

www.change.org/p/rfk-jr-mus...

Histopathologic Evaluation and Single-cell Spatial Transcriptomics of the Colon Reveal Cellular and Molecular Abnormalities Linked to J-Pouch Failure in Patients With Inflammatory Bowel Disease Total abdominal colectomy (TAC) with a staged ileal pouch-anal anastomosis (IPAA) is a common surgical treatment for ulcerative colitis (UC). However,…

🚨23% of ulcerative colitis patients w/ total abdominal colectomy w/ ileal pouch-anal anastomosis have pouch failure
❓Why?
🎯Post-procedure chronic inflammation & immune cell activity may be risk factors

@aga-cmgh.bsky.social #GIsky

www.sciencedirect.com/science/arti...

"NOFOs will no longer be included in the weekly NIH Guide Table of Contents subscription emails. You can use Grants.gov subscription services to receive notifications of new NIH funding opportunities." 🧪

grants.nih.gov/grants/guide...

Both applications are due on September 18th, so about 1 month away! If you need help preparing an application, I am available for very small contract projects, like grant editing :)

$100k over 2 years to an established PI working on novel approaches in gastric cancer

gastro.org/research-and...

New RFPs from AGA:

$40k over 1 yr for an ECI (with a CDA, e.g., NIH K) studying the pathogenesis, prevention, diagnosis, or treatment of digestive cancer

gastro.org/research-and...

AI Eroded Doctors’ Ability to Spot Cancer Within Months in Study Artificial intelligence, touted for its potential to transform medicine, led to some doctors losing skills after just a few months in a new study.

“The AI in the study probably prompted doctors to become over-reliant on its recommendations, ‘leading to clinicians becoming less motivated, less focused, and less responsible when making cognitive decisions without AI assistance,’ the scientists said in the paper.”

I obtained an early copy of the government's new food pyramid

RFK Jr: “We're developing a universal vaccine at NIH which is a vaccine that addresses the entire phylum of viruses.” “It's a vaccine that mimics natural immunity and it is effective against any kind of mutation.” “We believe it's gonna be effective against not only coronaviruses but also flu.” “And it's gonna be a much safer and a much more effective vaccine.”

RFK has announced that he is developing a vaccine against all viruses. Yes, every single one. The whole, uh, "phylum"

Pfizer, American Gastroenterological Association issue RPF for new research areas to improve diagnosis and treatment of inflammatory bowel disease Pfizer, American Gastroenterological Association issue RPF for new research areas to improve diagnosis and treatment of inflammatory bowel disease. Grants of up to $60,000 will be awarded in support o...

#GIsky Pfizer and the AGA are offering a new grant opportunity that will support IBD research

Areas of interest:
🌎Real-world data to model IBD
🧬S1P receptor modulators
🖥️Novel methods of diagnosis & monitoring

philanthropynewsdigest.org/rfps/rfp1813...