Shivani Dharmadhikari

Cooperation between cortical and cytoplasmic forces shapes planar 4-cell stage embryos - preLights How to make a 4-cell square ascidian embryo? Cytoplasmic pulling rotates centrosomes, cortical forces lock the plane.

How to make a 4-cell square ascidian embryo? Cytoplasmic pulling rotates centrosomes, cortical forces lock the plane.

Corentin Mollier & Shivani Dharmadhikari highlight a #preprint from Silvia Caballero-Mancebo & team @rdumollard.bsky.social

#preLight ⬇️
prelights.biologists.com/highlights/c...

It was only for the 24th and 25th actually (so over the last weekend)!

It’s fills you with childlike wonder and delight to see what you see under the microscope all the time on these magnificent walls and to see it shared with everyone who doesn’t do science(as a profession)☺️ #actin#cytoseleton#cells#protrusions

One the most lovely combinations of science and art I have been to in a long time at Musée d’Orsay☺️✨ by the @manuelthery.bsky.social #cytomorpholab

#LivingArchitectures
We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay.
www.musee-orsay.fr/fr/agenda/ev...
Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night.
-> Two shows on the 24th and 25th of January.

A fun way to recover embryos on a grey Parisian day 🌧️🐭

It was lovely to know you and everyone else from your lab too ☺️

I am sure I am missing to tag so many of them here but hopefully my friends from the course will help me tag them:) with that being said MBL Physiology 2025 will be a lovely memory to cherish! ☺️

With social hours spent doing foldscope duels @prakashlab.bsky.social @yannis-reignier.bsky.social and solving puzzles.. watching whales and late night swims under the stars 🌌🌊🤫 with my cohort @edwardwheeler.bsky.social @vibhaka.bsky.social @rnadavid.bsky.social @michaelcchung.bsky.social ....

And the course manager - @samjlord.bsky.social 💪 and the lovely course assistants Peter Yunker, Pascal Keum-jae, Noah Kohn

Throughout the summer we had the support of very talented microscopists - Joe Brzostowski, @tanner-fadero.bsky.social , Nico Stuurman! 🔬😊

And we finished with collectives of collectives and electrocuting things ⚡ with @djcohen.bsky.social, Isaac Breinyn, Sameeksha Rao, Yubin Lin and Charlie Duclut

Rotation 2 continued with amazing tools to look at organelles inside the cell with @cohenlaboratory.bsky.social, Sherry Hsu, Kajal Kamble, @mczanellati.bsky.social! Had a cool group to troubleshoot with Safal, Greg, Alex, Aaron, @edwardwheeler.bsky.social , Illeana and @lucasphilipp1.bsky.social

Rotation 1 introduced me to the amazing Physarum 😍💛 Amy, Zach, Ameya, @haysconun.bsky.social and Vita from @gladfelterlab.bsky.social were encouraging TA's.

started with skills week with - @tanner-fadero.bsky.social , @jlazzaridean.bsky.social, Deepak Krishnamurthy, @chueschen.bsky.social, Veronica, David and Bob

Spent a memorable summer at Physiology course at @mblscience.bsky.social Very coooool science with some lovely people! Thanks @brangwynnelab.bsky.social and @gladfelterlab.bsky.social for being amazinnnng course coordinators! 🧵

I'll kick off my bsky profile with a great 3D fluorescence microscopy time-lapse. My buddies Joe Brzostowski and Rachel Stadler (NIH) acquired this on their #snoutscope that I helped them build.

Shown is a fluorescent actin marker in Dictyostelium. Joe and Rachel called this "The Mark of Zorro!"

MBL scientists use skates and their embryos to study skeletal development. By shining a light through egg cases, scientists can watch the entire maturation process.

Learn more about skates as a research organism here: bit.ly/3Rmvq3F

📹 Bioquest

The one and only Manu @prakashlab.bsky.social
inspiring @mblscience.bsky.social Physiology students at this morning's lecture.

A great morning with the @mblscience.bsky.social
Physiology students after my talk today.

We may not have really squared the circle — but we came close! 😉 In our @NaturePhysics paper w/ @fakhrilab.bsky.social, light-triggered membrane excitability enables programmable shapes — a step toward engineering living matter.
🔗 www.nature.com/articles/s41...
#biophysics #syntheticcell #softmatter

Is there a pattern of how they arrange in the drop or have I been staring through the microscope for far toooo long? 🧐😁#beautifulembryos

If you're in Europe you can watch it in French here: www.arte.tv/fr/videos/11...

That’s beautiful! What did you use to stain the membrane?

New cell line = New cell morphologies to explore!

This hepatic cell line has fully invested into membrane protrusions!

Actin is shown in 🟦 and DNA in 🟧

#FluorescenceFriday
#SciArt

A woman studies embryos for decades, struggles for funding and respect. She publishes under her husband’s name, until they divorce. A single mother, she moves across an ocean to continue her studies. It all sounds quite modern, until you learn that she also worried she’d be burned as a witch. 🧵 1/15

I think you definitely could☺️

Lovely work on shape evolution! Check out the story below:)

Couldn’t help but hum.. Round like a circle in a spiral, like a wheel within a wheel…🎶the windmills of your mind!

bsky.app/profile/roug...