GitHub - pogorely/TIRTL: Code for paired TCR data analysis from TIRTL-seq experiments
Code for paired TCR data analysis from TIRTL-seq experiments - pogorely/TIRTL
Code is on the Github github.com/pogorely/TIRTL, and there is a new R package with more TIRTL-seq data analysis and visualization functions (actively developed by @nick-clark-bioinfo.bsky.social), early version is ready for testing github.com/NicholasClar...! Congrats to TIRTL team!(4/4)
25.11.2025 22:38 β π 0 π 0 π¬ 0 π 0
Bring structure to your research - protocols.io
A secure platform for developing and sharing reproducible methods.
Fully manual 96-well protocol is also at protocols.io: www.protocols.io/view/tirtl-s.... Requires only manual multichannel pipettes, no specialised equipment! (3/4)
25.11.2025 22:38 β π 0 π 0 π¬ 1 π 0
TIRTL-seq: deep, quantitative and affordable paired TCR repertoire sequencing - Nature Methods
TIRTL-seq is a high-throughput method for paired T cell receptor sequencing at the cohort scale.
Two complementary studies from our group out today: a therapeutic peptide vaccine trial for fibrolamellar carcinoma (FLC) & TIRTL-Seq, our robust method for deep quantitative paired TCR sequencing aπ§΅w/ @markyarchoan.bsky.social & @pogorely.bsky.social www.nature.com/articles/s41...
24.11.2025 21:36 β π 30 π 13 π¬ 4 π 0
MS Neurologist, T cell immunologist, UCSF Dept of Neurology, Weill Institute for Neurosciences.
All posts are my own and not on behalf of UCSF
π¬π§ immunulogist in πΊπΈ | instructor @ MGH/HMS | TCRs and pMHC
Technically a James | Κ€eΙͺmi hΙΓ°ΙΛ | he/him
@jamimmunology in the old place
papers, tools, & 3d printed labware here: https://jamieheather.github.io/
Biophysicist interested in immunology.
Professor at Goethe University Frankfurt | Frankfurt Cancer Institute.
https://agimkeller.github.io
Computational immunologist @Genentech | B cells > T cells | PhD @DKFZ
postdoc at UW Genome Sciences with βͺ@wsdewitt.github.io β¬ | previous: PhD student with @matsen.bsky.social at Fred Hutch β¬ |
β‘ computational biology, immunology
Structural and molecular immunology and protein biophysics at the University of Notre Dame. T cell receptors, MHC proteins, specificity, and cross-reactivity. Plus drums, odd time signatures, Iron Maiden, and much Rush. Opinions mine alone.
bmblab.nd.edu
Computational immunologist @CHUV.
scRNA, TCR and BCR
Immunologist exploring TCRs & the immune system in immune-compromised patients. Background in molecular biology & computer science. Expert in R & Python. Emerging Research Data Management enthusiast. Team lead of immune-diagnostic lab.
Research Associate at Imperial College London & Honorary Research Fellow at UCL | Immunology | TCR repertoire
American/Swedish Biomedical Scientist studying immunology and cancer. My favorite cell atlases say βhere be dragonsβ on the UMAPs. @karolinska institute
https://scholar.google.com/citations?hl=en&user=_owb98cAAAAJ&view_op=list_works&sortby=pubdate
Immunologist and Professor at the Doherty Institute and University of Melbourne
Postdoc in Westra lab, University of Exeter, Cornwall, UK
Interested in host-MGE and MGE-MGE interactions.
πTemperate phages!
Lab studying molecular evolution of proteins and viruses. Affiliated with Fred Hutch & HHMI.
Opinions are my own and do not reflect those of my employer.
https://jbloomlab.org/
MD Microbiology & Virology. Understanding & Engineering Human T Cell Immunity in Erlangen, Germany (www.schoberlab.de). Cycling. BVB. Cinema. Family.
We are the members of the Diamond lab at WUSM: cutting edge virology, immunology and microbiome research, and antiviral vaccine and therapeutics development.
Wild immunologist who never forgets the parasites. Advocate for justice. Mate of cryptozoologist. Daughter, sister, niece, aunt, wicked stepmother, & worldβs first Grandrea. Marching for the ERA since age 6. True.
Immunologist. T cell exhaustion, immunotherapy, Immune Health.
Pediatrician &
Professor of Pediatric Immunology
Human Systems Immunology
MRC LMS, Imperial College London
& Karolinska Institutet
Focused on innate immune mechanisms governing pathogenesis of disease and on NK-cell based therapies for disease. Opinions expressed are Dr. Waggoner's alone and not on behalf of lab staff or employer.
