Immune Sex Differences

Our second annual meeting - please save the date and distribute

See you in less than two hours!

Join us this Friday!

Epidermal growth factor receptor controls sex differences in lung type 2 responses to inhaled allergen Female mice have exacerbated, EGFR-dependent lung type 2 immunity when exposed to inhaled house dust mite throughout sexual maturation.

Epidermal growth factor receptor controls sex differences in lung type 2 responses to inhaled allergen | Science Immunology www.science.org/doi/10.1126/...

Sex Bias in IL-10 Production by Type I Regulatory T Cells Regulated by PI3K/mTOR Signaling | Neurology Neuroimmunology & Neuroinflammation Background and ObjectivesMultiple sclerosis (MS) is more prevalent in women, with a female-to-male ratio of 3:1. The molecular mechanisms driving this sex difference are still mostly unknown. MS resul...

In this study, we highlight a sex difference in Type I regulatory T cells, with potential translational application in MS to be further explored.

www.neurology.org/doi/pdf/10.1...

@saniya-kari.bsky.social @sexdiffimmunity.bsky.social

Sex differences in health and disease

Some of us may be interested to meet sooner, so #EESSexDifferences @EMBLEvents may be of interest. It goes beyond the immune system, but still www.embl.org/about/info/c...

Thanks to all for participating in the first EFIS sex differences in the immune system meeting, and thank you @darraghduffy.bsky.social @milieuinterieur.bsky.social for the generous hospitality and for inviting us to your fascinating annual meeting.

Today we meet face to face for the first time!

Surprisingly, it is not yet obvious to all researchers and funding agencies that sex and gender matter in research, and should be recorded and addressed properly. So we wrote it authors.elsevier.com/c/1lxSmbah1w...

Decoding sex differences in human immunity through systems immunology Abstract. Immune function varies widely across humans. Biological sex is a key factor underlying human immune variability, with men presenting with more se

‼️Our first review is out‼️

Decoding sex differences in human immunity through systems immunology shorturl.at/EsAkE

We discuss how #SystemsImmunology decodes #SexDifferences in #HumanImmunity, paving the way for tailored, sex-informed treatments.

Excellent work by @resabut.bsky.social & Tianze Cao!

Join us for today's seminar!

Come join our next seminar! Register at forms.gle/XYuwtNjqa2hP...

Cell Line-Specific Estrogen Responses Uncover Functional Sex Differences in Murine Macrophages - PubMed Background RAW 264.7 (male-derived) and J774A.1 (female-derived), are widely used in immunology research, yet their responses to gonadal hormones remain poorly understood. Gonadal hormones, particular...

Even in cell lines, sex matters pubmed.ncbi.nlm.nih.gov/40630528/

In 40 minutes!

Join our next online seminar

🗓️ Date: Friday, June 27th 2025
🕑 Time: 14:00 CET
💻 Location: Online (forms.gle/XYuwtNjqa2hP...)

Presenters
Jamie Sugrue (Darragh Duffy group) "Sex differences in diverse type I interferon responses"

Léa Ferrayé (Jean-Charles Guéry group) "Defect of X Chromosome Inactivation increase Tlr7 expression and underlies systemic autoimmunity"

Join our next online seminar

🗓️ Date: Friday, June 27th 2025
🕑 Time: 14:00 CET
💻 Location: Online (forms.gle/XYuwtNjqa2hP...)

Sex and Gender This open access book provides an interdisciplinary perspective on the study of sex and gender and suggests directions for future research in this field.

Sex and gender - a free book of possible interest link.springer.com/book/10.1007...

Our first meeting is in Paris on October! Do not forget to register - Registration ends June 1st.

Come join us this fall in Paris

Sex related differences in immunology researchers

💥 Inspired by the incredible energy of #DayofImmunology2025 yesterday?
Now it’s your turn!
🏆Apply now for the Day of Immunology Awards to showcase the powerful events you’ve organized to celebrate #immunology and this year’s theme: #BrainandImmunity🧠 🔬

@iuis-online.bsky.social @dgfi-org.bsky.social

Better late than never - happy #dayofimmunology yesterday, and let's mark our calendar for April 29 2026. If you wish to meet us before, we meet in October in acrobat.adobe.com/id/urn:aaid:...

In just three hours...

EFIS-IL immune sex differences charter Sex and gender differences in the immune system have gained increased attention over the past years, and are fundamental for the understanding of immune variation. The European Federation of Immunolog...

If you already registered and did not get the reminder email, please add "efis.isd@gmail.com" to your contacts.

If you have not registered yet, register at forms.gle/XYuwtNjqa2hP...

Second presenter

Joan Escrivà Font, Ph.D. candidate (Camila Consiglio group, Sweden)
"Disentangling estradiol's effects on immunity: a systems-level approach in rhesus macaques

First presenter

Sneha Kanungo, Ph.D. candidate (Tal Pecht group, Germany)
"Immune sex differences in blood transcriptome are shaped by environmental factors in healthy Tanzanians"

Our second online seminar will take place next week:

🗓 Date: Friday, April 25th 2025
🕒 Time: 14:00 CET
💻 Location: Online

Amazing study showing protective effect of herpes zoster vaccination against dementia with interesting sex differences @sexdiffimmunity.bsky.social
#vaccines work! #immunosky #medsky

EFIS-IL immune sex differences charter Sex and gender differences in the immune system have gained increased attention over the past years, and are fundamental for the understanding of immune variation. The European Federation of Immunolog...

The second great talk was given by @stefaniadelprete.bsky.social from @odom_lab. To join our next seminars, go to forms.gle/XYuwtNjqa2hP...