Helldesk person "the meter reading stays the same, 1251. Meter is working fine, are your other appliances functional?"
AAAAARGH.
@infinitescream.bsky.social
02.03.2026 17:03 —
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I'm in helpdesk hell. Trying to show Thames Water there is a leak before the water enters my home, internal stop valve closed and the water meter keeps on increasing, but not gushingly, so only the digits after the whole m3 increasing (1251.177 to 1251.289 in less than 3h)
02.03.2026 17:03 —
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Had to go via a Thames Water Whatsapp AI chatbot today. I wanted to rip it a new arsehole within 2 minutes.
Utterly useless. Now waiting for the assigned human to respond...
02.03.2026 12:03 —
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"US says Iran’s ‘reckless’ attacks threaten regional stability"
Eh... no. US and Israel's reckless attacks threaten regional stability. I have no sympathy for the Iranian government, but it is the US and Israel that are the aggressors.
02.03.2026 11:57 —
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Manual device
02.03.2026 09:22 —
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My students may be helped by it as well...
01.03.2026 22:00 —
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The quickest way to stop any Iranian retaliation would be to stop bombing them.
Arresting the Trumpist idiots and Nethanayu clan for war crimes would help.
#duh
01.03.2026 21:59 —
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Corner of a lap mat padded mat with a fabric of red chilli's repeating all over the fabric.
Now available to buy, red chilli's lap mats.. craftysharp.etsy.com/listing/4360...
01.03.2026 20:04 —
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I switched the channelto Indycar,so bored.
01.03.2026 21:06 —
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Rapid and reliable diagnosis of mucormycosis using colorimetric loop-mediated isothermal amplification
ABSTRACTCurrent diagnostic approaches for mucormycosis are often limited by low sensitivity and prolonged turnaround times, which result in delayed treatment and poor clinical outcomes. We developed a novel diagnostic method utilizing a colorimetric loop-mediated isothermal amplification (LAMP) assay for the rapid and sensitive detection of mucormycosis. The assay incorporates specifically designed primers capable of detecting as low as 0.001 picograms (pg) of spiked genomic DNA from Mucorales fungi. This LAMP assay demonstrated a high sensitivity of 98% and a 100% specificity of detecting fungal ribosomal DNA (rDNA) in bronchoalveolar lavage (BAL) samples collected from mice infected with Mucorales fungi (n = 48) or from an uninfected control group (n = 15). To align the assay with clinical antifungal therapy, a subset of infected mice was treated with either liposomal amphotericin B (LAMB) or a combination of LAMB and a humanized monoclonal antibody (VX-01) targeting the Mucorales-specific surface protein CotH3. Consistent with the treatment efficacy, the LAMP assay detected significantly lower fungal burdens in BAL samples from mice receiving the combination therapy compared to those treated with LAMB alone or placebo. Further validation was conducted using BAL samples from patients diagnosed with mucormycosis (n = 24) or aspergillosis (n = 17). The assay demonstrated a sensitivity of 79% and a specificity of 94%. These findings highlight the diagnostic potential of this LAMP-based assay as a point-of-care. Its high sensitivity, specificity, and rapid turnaround time position this assay as a promising tool for early and accurate detection of mucormycosis, with the potential to improve patient management and clinical outcomes.IMPORTANCEMucormycosis is a rapidly progressive and fatal fungal infection. Timely diagnosis is critical for effective treatment, yet current diagnostic tools are slow, insensitive, or require complex laboratory procedures. In this study, we developed and validated a colorimetric loop-mediated isothermal amplification (LAMP) assay that enables rapid and reliable detection of Mucorales DNA directly from bronchoalveolar lavage (BAL) specimens. The assay demonstrated high sensitivity and specificity in both experimental mouse models and clinical samples, producing results within 1 h without the need for sophisticated equipment. This simple, robust, and cost-effective molecular diagnostic tool holds great potential for early detection of mucormycosis, facilitating prompt antifungal therapy and improving patient survival.
New LAMP assay detects mucormycosis with 98% sensitivity (mice) 🐭, 79% (patients) 🧑⚕️ & 94-100% specificity 🎯 in ≤1h, aiding early treatment & better outcomes.⏱️💉
27.02.2026 05:30 —
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Whole genome analysis of azole-resistant Candida tropicalis candidemia outbreak in a haematology ward: a single centre experience https://pubmed.ncbi.nlm.nih.gov/41758109/
01.03.2026 11:21 —
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One word: Windrush. Yes, they would be deported under the fascists.
01.03.2026 11:57 —
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Did you let that bat bite you? You are foaming at the mouth.
01.03.2026 11:10 —
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Why John isn't working for the Daily Sturmer or Daily Fail, it's just amazing what kind of fascist claptrap he keeps on printing.
More Shabana Mahmoods is like saying his house needs more rabid Bully XLs.
01.03.2026 11:08 —
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Another example that Laurie Magnus has zero integrity and less spine of a wet spaghetti. He would have exonerated Mandelson if he would have been an minister.
28.02.2026 20:22 —
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That ethics advisor has less spine than soft spaghetti...
28.02.2026 20:08 —
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Releases · artic-network/peartree
Contribute to artic-network/peartree development by creating an account on GitHub.
Whilst web apps are quite handy as they don’t need installing, they can be annoying (e.g., when you accidentally close the window). So you can also download desktop apps here: github.com/artic-networ...
28.02.2026 19:01 —
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Nice. As a frequent user of Figtree, I will certainly try this 🙂
28.02.2026 19:25 —
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YouTube video by jacarbo77
Blackadder - Directions in Wales
www.youtube.com/watch?v=hnl3...
They gather it is a ghastly place 😇
28.02.2026 15:36 —
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McSweeney has just been pushed uit with a parachute, Lammy and other cabin personnel are running around like headless chickens shouting "AI will save us".
Such a self-inflicted mess.
28.02.2026 12:04 —
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I'm just watching a recording of Air Crash Investigations, where a plane flies into a mountain.
I can foresee the Labour cockpit recording, with captain Starmer ignoring any warning signs from the ACAS system, co-pilot Mahmood shrieking "there are foreigners among the passengers, kill kill kill"..
28.02.2026 12:04 —
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A very bad joke. The entitlement is just nauseating.
28.02.2026 10:42 —
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A toaster still can be useful. Mahmood is not.
28.02.2026 10:39 —
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She is dumber than RFK Jr, who at least has a brain worm and toilet seat coke sniffing as "excuse".
27.02.2026 23:04 —
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McSweeneh is gone, but his team is still there? So many clueless people.
27.02.2026 21:54 —
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Hope you are enjoying yourself!
27.02.2026 20:06 —
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