Ian Duguid

Fantastic to see this collaborative work with Hopi Hoekstra out in Nature (tinyurl.com/3at3zvby). Lead by @felixbaier.bsky.social and @katjareinhard.bsky.social. Not possible without @bramnuttin.bsky.social , Chen Liu and @arnausd.bsky.social.

Excited to see where this work leads.

Barcoded Rabies In Situ Connectomics for high-throughput reconstruction of neural circuits Sequencing of oligonucleotide barcodes holds promise as a high-throughput approach for reconstructing synaptic connectivity at scale. Rabies viruses can act as a vehicle for barcode transmission, than...

1/ Mapping synaptic connectivity between individual neurons is extremely laborious. We developed BRISC, a new method that makes it possible to map inputs onto 100s of neurons in the same animal in a matter of weeks! Led by Alex Becalick and @antblot.bsky.social. 🧵

www.biorxiv.org/content/10.1...

📢Fabulous new paper from @tspiresjones.bsky.social, @clairedurrant1.bsky.social & team describes new mechanisms in Progressive Supranuclear Palsy, suggesting that targeting tau in synapses is a promising approach for future treatments.

Full paper➡️www.nature.com/articles/s41593-025-01992-5 🧠

Don't miss this upcoming informal gathering on the theme of SEARCHING FOR PRINCIPLES IN MOTOR CONTROL on Sept 23-24, 25 in Sorbonne University. It will enable you to present your work to the French motor community. Registration is free! motorconference.sciencesconf.org

🎉 Congrats to @cristina-mtz-glz.bsky.social for winning 1st prize in the BNA Photo Competition!

Her image of a whole mouse brain labelled for tyrosine hydroxylase, captured with light-sheet microscopy, will feature in the BNA 2025/26 calendar

@britishneuro.bsky.social
@edinunineuro.bsky.social

🚨PhD position opening on a project aimed at defining the role of different sources of sensory information on locomotor control. 📢 ⬇️
www.mdc-berlin.de/zampieri#t-j...

Is it true you use only 10 bits / s of your brain?
@andpru.bsky.social and I provide a motor systems perspective on a proposed speed limit for human information processing. Out today in
@natneuro.nature.com:
www.nature.com/articles/s41...

Two postdoc positions in the lab within the ERC Synergy project "Chronology" in collaboration with S. Ostojic, M. Jazayeri and V. van Wassenhove @virginievanw.bsky.social . Two focuses: sound sequences representations across the brain & novel all-optical technology. Contact: brice.bathellier@cnrs.fr

Sounding the alarm on pseudoreplication: Q&A with Constantinos Eleftheriou and Peter Kind Most studies of neurological disorders in mice erroneously treat multiple samples from a single animal as independent replicates, according to a new analysis. But scientists and journals can take…

A statistical error known as pseudoreplication appears in more than half of recent mouse studies on neurological disorders, according to a new study. Peter Kind and Constantino Elfetheriou tell Lauren Schenkman why researchers should pay attention.

www.thetransmitter.org/pseudoreplic...

Motor learning refines thalamic influence on motor cortex - Nature Imaging and optogenetics in mice provide insight into the interplay between the primary motor cortex and the motor thalamus during learning, showing that thalamic inputs have a key role in the executi...

Our paper is out in Nature.

By examining various inputs to the motor cortex during learning, we found that thalamic inputs learn to activate the cortical neurons encoding the movement being learned.

Tour de force by Assaf in collab with Felix and Marcus. Congrats!

www.nature.com/articles/s41...

Illuminating the dark. Tavakoli, Lyudchik, and Danzl discuss a close-up image of the hippocampus—a brain region responsible for memory formation and spatial navigation—in the microscopy room at ISTA. © ISTA

Manual reconstruction of 658 neuronal structures, revealing their complex shapes and interwoven arrangement. © Tavakoli, Lyudchik et al./Nature

Deep learning techniques from Google Research predicting neuronal structures and their positions within the brain tissue. © Tavakoli, Lyudchik et al./Nature

Authors from the Danzl group. From left to right: Mojtaba R. Tavakoli, Julia Lyudchik and Johann Danzl. © ISTA

ISTA scientists and Google Research unveil LICONN: a new expansion microscopy method that can reconstruct mammalian brain tissue with full synaptic detail using light microscopes. This method could transform how we study the brain’s networks.

@nature.com

Read more: https://bit.ly/44f0euV

Cellpose3 uses deep learning to enhance degraded images for more accurate segmentation.

www.nature.com/articles/s41...

🖥️ A new version of #Cellpose – the popular tool developed by @computingnature.bsky.social & @marius10p.bsky.social that maps the boundaries of diverse cells in microscopy images – now works on less-than-perfect pictures that are noisy, blurry, or undersampled.
🔗 www.janelia.org/news/newest-...

We are pleased to be partnering with The UKRI AI CDT in Biomedical Innovation at the School of Informatics (University of Edinburgh). These PhD projects have a strong translational focus and seek to develop & apply AI approaches to biomedical domains ✨.
Apply by 20 Jan www.ai4biomed.io/how-to-apply/

There’s just under 2 weeks to apply for our PhD studentships! Join our dynamic community where we provide an annual stipend of £25K, plus tuition fees (inc. international) 🧠.

Apply by 26 January and start your journey with us: sidb.org.uk/phds/

@edinburghmedschool.bsky.social

Interested in how #cortex contributes to motor control and how this process is altered in #Parkinsons ?

The Jaeger lab at #Emory is hiring!

Job IDs 140544 and 140545 here: staff-emory.icims.com/jobs/

#neuroscience #HigherEdJobs #AcademicJobs #ScienceJobs #ParkinsonsResearch #postdoc

There's still time to apply to the Paris NeuroCourse.
This year we'll have two 2-photons, miniscopes, neuropixels, voltage imaging, patch-clamp, and of course an amazing list of lecturers: parisneuro.ovh
2 weeks of neuroscience lectures and techniques in Paris!

The Annual Meeting of the Japan Neuroscience Society (July 24-27, 2025) and organizers are inviting scientist from abroad. They give travel awards to enthusiastic, leading, non-Japanese neuroscientists coming to present their work- information below:

neuroscience2025.jnss.org/en/internati...

Yay - superb, well done you!

Superb - many congratulations. Well deserved.

Are you interested in pursuing a PhD at the interface between Ai and Systems Neuroscience. If so: www.ai4biomed.io/research/pro... - a collaborative venture between UKRI Ai CDT in Biomedical Innovation and Simons Initiative for the Developing Brain (www.sidb.org.uk ) at The University of Edinburgh.

Could I be added? Many thanks.

Yes please.

Yes please.

Hidden state inference requires abstract contextual representations in the ventral hippocampus The ability to use subjective, latent contextual representations to influence decision-making is crucial for everyday life. The hippocampus is hypothesized to bind together otherwise abstract combinat...

Huge congrats to @karyna-mi.bsky.social for her paper published today in Science! She found that the hippocampus is really important for a key strategy we use to make decisions called hidden state inference! 🧪 🧠https://www.science.org/doi/10.1126/science.adq5874 1/7

🚨 PhD opportunity alert! 🚨

Join our lab @sidb-edinburgh.bsky.social in beautiful Edinburgh! We study the neural mechanisms underlying flexible decision-making using cutting-edge experimental and computational approaches.

We’re recruiting for two fully funded PhD positions. Details below 👇

Fantastic news, congrats!

Does brain activity cause consciousness? A thought experiment The authors of this Essay examine whether action potentials cause consciousness in a three-step thought experiment that assumes technology is advanced enough to fully manipulate our brains.

The craziest paper I have ever done is this thought experiment with Albert Gidon and Matt Larkum.

In the first journal, reviewer 1 recommended that we should not try to publish this; reviewer 2 called it "wacky". Thanks for the motivation: A sequel is coming up!

journals.plos.org/plosbiology/...