JACC Journals

Exciting science is live! 🚀 #JACCJournals are publishing top research from #AHA25 Scientific Sessions, with new papers across multiple journals showcasing some of the hottest trials and breakthroughs in cardiovascular medicine.

Dive into the latest discoveries now: https://bit.ly/4o1EMkg #CardioSky

New ACC Concise Clinical Guidance updates best practices for diagnosing and managing transthyretin amyloid #cardiomyopathy, highlighting disease-modifying and HF therapies plus future directions. https://bit.ly/49nYX7m

#JACC #Amyloidosis #ATTRCM #HeartFailure #CardioSky

🚨 #AI-based #ECG analysis significantly improved #STEMI detection, reduced false activations, and enhanced recognition of non-conventional presentations. This supports integration of AI-based ECG analysis into acute chest pain pathways. https://bit.ly/4hopPpT

#TCT2025 #JACCINT #CardioSky

In the randomized PROCTOR trial, SVG #PCI was assoc with improved 1-yr clinical outcomes compared with native vessel PCI, primarily driven by lower rates of PCI-related MI & clinically driven target coronary territory #revascularization https://bit.ly/4ogyuxh

#TCT2025 #JACC #cvMI #cvCABG #CardioSky

The STRIVE trial shows intracoronary low-dose alteplase doesn’t improve outcomes in #STEMI with large thrombus and may raise arrhythmic risk—closing the door on this adjunctive fibrinolysis strategy during primary #PCI. https://bit.ly/4oSfzc7

#TCT2025 #JACC #MACE #CardioSky

Despite Class I guideline indications, most patients with severe aortic regurgitation remain untreated. This #JACC review outlines advances in diagnosis, surgical refinements, and emerging transcatheter options to bridge this gap. https://bit.ly/3WPcVHM

#TCT2025 #vhdAR #CardioSky

In patients with de novo coronary artery disease, #DCB angioplasty with rescue stenting was associated with a higher rate of Device-oriented Composite Endpoint compared to intended DES implantation regarding DoCE at 3 years. https://bit.ly/4nePRNp

#TCT2025 #JACC #cvCAD #CardioSky

Findings from SUMMIT-MAC show that #TMVR using the Tendyne system significantly improved #heartfailure symptoms and QoL in patients with severe mitral annular calcification. Read the highlights: https://bit.ly/4qCxF3t

#TCT2025 #JACC #CardioSky #MedSky @jaccjournals.bsky.social

In this first report of the primary outcomes of the SUMMIT-MAC clinical trial, #TMVR with Tendyne led to successful treatment of mitral valve disease due to MAC and significant improvements in #heartfailure symptoms and #QoL. https://bit.ly/4ovW0pz

#TCT2025 #JACC #SUMMIT #CardioSky

🩸 New #JACCBTS study reveals estrogen’s dual effects on microvascular health differ by sex

⚖️ A balanced ceramide: S1P ratio is 🔑 to endothelial health
🧬 May explain why long-term hormone exposure can 📈 CV risk

🔗 https://bit.ly/43Ct5In

#APSSexDiff2025 #CardioSky #MedSky

The DOSE Trial: In a multicenter RCT (n=1,001), operator radiation exposure was compared between left distal radial vs right transradial access at left wrist, head, and chest. No significant differences. https://bit.ly/43zuP59

#TCT2025 #JACC #CardioSky

FFR-guided #PCI using zotarolimus DES provides significantly better long-term value than CABG for treatment of patients with multivessel CAD, with equivalent clinical outcomes at substantially lower cost. https://bit.ly/47vJgJS

#TCT2025 #JACC #cvCABG #cvCAD #CardioSky

Big ideas. Breakthrough science. Real-world impact 💡

The #JACCJournals family brings interventional innovation to #TCT2025, from late-breaking trials to transformative device advances 👉 https://bit.ly/3LhtZ6I

#JACC #JACCINT #JACCCaseReports #JACCAdvances #CardioSky @crfheart.bsky.social

Even small changes in #alcohol intake can impact #BP. 🍷➡️📉 Reducing or stopping drinking may lead to meaningful BP improvements and better management. https://bit.ly/43rOmEA

#JACC #Hypertension #BloodPressure #CardioSky #MedSky

Big news for #JACCJournals! #JACCAsia and #JACCAdvances are approved for #ImpactFactor, with first rankings being issued in June. Launched in 2021 and 2022, respectively, both journals are shaping the future of #Cardiology. https://bit.ly/49d912U

#CardioSky #MedSky @csilvers.bsky.social

#JACCCardioOnc continues to rise, with a new Impact Factor of 13.4 and a top 10 ranking. The journal’s growing influence highlights its role as a leading platform for cutting-edge #CardioOnc research. https://bit.ly/43nTHwF #CardioSky #MedSky

#JACCCaseReports is in Denver for #ACCQuality25! Don’t miss the latest case studies released alongside the conference, showcasing innovative approaches to improving cardiovascular care: https://bit.ly/46SH9Qh #CardioEd #CardioSky

The latest issue of #JACC features Dr. Milton Packer’s exploration of the “#adipokine hypothesis,” linking adipocyte biology to #HFpEF. Along with commentaries, it also debuts an interactive tool for exploring molecular roles in HFpEF.

Explore the issue: https://bit.ly/4obvBx0 #CardioSky #MedSky

In the sotalol-eligible patients, ablation led to lower risk of the primary composite endpoint. In the amiodarone-eligible group, efficacy outcomes were comparable between ablation and amiodarone. Adverse events were more marked among patients randomized to amiodarone. https://bit.ly/4mXfS3O #JACC

Explore #JACCCardioOnc’s new expert content hub featuring reviews, primers, societal statements, & How To manuscripts. These provide practical guidance for diagnosing & managing clinical scenarios in cancer care & survivorship. https://bit.ly/46SMQMM

#CardioOnc #CardioSky #MedSky

#DAPT after valve-in-valve #TAVI may be associated with a lower one-year incidence of stroke, while no significant difference was observed for other major ischemic and bleeding outcomes or for premature valve deterioration. https://bit.ly/46zU4Gx

#GISE46 #JACCINT #CardioSky

We're seeking a visionary leader in CV research to serve as the next Editor-in-Chief of #JACCAdvances. Applicants should have an academic appointment, a strong scholarly record, leadership experience, & knowledge of open access publishing.

Apply: https://t.co/u69ewQHR6G

🎥 Dr. Fred Kusumoto shares the importance of clinical guidance beyond traditional #ClinicalGuidelines, & shares takeaways from 🆕 expert consensus decision pathway on tricuspid regurgitation (TR).

📖 Read: https://bit.ly/4ncVbSp

#JACC #ACCClinicalDoc #CardioSky #vhdTR @jaccjournals.bsky.social

More than 99% of heart disease cases have a risk factor you can address before you get sick, study shows | CNN In almost all cases, there are signs leading up to cardiovascular disease. You can start treating the risk factors now, experts say.

A recent #JACC study found that 4️⃣ CV risk factors – BP, blood sugar, #Cholesterol, & smoking – could serve as warning signs before cases of #CVD, #HeartFailure, or #Stroke occur. www.cnn.com/2025/09/29/h... @cnn.com

New 2025 ACC scientific statement reviews the role of inflammation in #CVD, covering #atherosclerosis, #heartfailure & #pericarditis. It highlights residual risk, screening, management & new therapies.

Get the details in #JACC: https://bit.ly/46ORETq #CardioSky

Selective in vitro enhancement of cardiac myosin motor function and myofilament force generation by danicamtiv prompted clinical evaluation. A short course of danicamtiv was generally well tolerated in participants with #DCM https://bit.ly/4mE3vcM

#HFSA2025 #JACC #cvGenetics @jimjanuzzi.bsky.social

Acoramidis 📉 cumulative CV outcomes in #ATTRCM vs placebo, w/ numerical differences by month 1 & 📈 through month 30 (53 events avoided/100 pts). Nearly 1/4 of events occurred in the first 6 months, underscoring the need for timely Tx https://bit.ly/4gLv5DG

#HFSA2025 #JACC #CardioSky

Between 2021-2025, relatively few AHFTC fellowship programs matched most applicants. Applicants prioritize markers of hospital reputation & #Hearttx volumes over regional disease burden or geographical considerations. https://bit.ly/4nHnWXP

#HFSA2025 #JACCHF #ACCHFT @eirangorodeski.bsky.social

📢 New in #JACC: ACC/AHA methodology statements on:
🔹 Core Principles & Development
🔹 Cost/Value (update)
🔹 FDA Processes

Together with Circulation, they provide the framework to keep guidelines rigorous, transparent & responsive.

🔗 Explore the statements: https://bit.ly/3IE4EDc #CardioSky #MedSky

At #UNGA80, experts shared the 2023 #GBDstudy, tracking #CVD trends in 204 countries since 1990. Full insights: https://bit.ly/4pxeDe6

🗨️ Dr. Krumholz: “Data should be a compass, not a mirror. We must focus efforts where they’re needed most. AI can transform care.”

#JACC #NHLBI @ihmeuw.bsky.social