Gladstone Institutes

Health Tech: Deepak Srivastava Of Gladstone Institutes On How Their Technology Can Make An… This convergence of AI, stem cell biology, and gene editing means that we no longer have to accept our genetic destiny. For the first time…

Gladstone president Deepak Srivastava is featured in Authority Magazine discussing how technology is transforming the future of medicine.

Portfolio — Hypothesis Fund The Hypothesis Fund enables scientists to take intelligent risks. To defy the predominant expectations in their field. To go after their big ideas.

Gladstone researcher Sukrit Silas is a 2026 Hypothesis Fund awardee. Silas is setting out to solve the longstanding challenge of predicting phage-bacteria compatibility. His project could transform how phages are harnessed to fight against antibiotic resistance.

YouTube video by Gladstone Institutes Discovery Spotlight | Red Blood Cells Soak Up Sugar at High Altitude, Protecting Against Diabetes

A new study, led by @ishahjain.bsky.social, shows red blood cells act as hidden glucose sponges in low-oxygen conditions, explaining why people living at high altitude have lower diabetes rates and pointing toward new treatments.

Cell Signals│Red Blood Cells Soak Up Sugar at High Altitude, Protecting Against Diabetes Plus, learn how Gladstone scientists are creating AI tools to accelerate life-saving discovery.

In our latest issue of Cell Signals, discover how red blood cells absorb glucose at high altitude to offer potential protection against diabetes, learn how Gladstone scientists are creating AI tools to accelerate life-saving discovery, and watch a behind-the-scenes video of a student intern.

Vitamin B2 and B3 nutrigenomics reveals a therapy for NAXD disease A nutrigenomics framework identifies genetic diseases amenable to vitamin B2 and B3 therapies. This approach nominates vitamin B3 as a therapy for NAXD deficiency, a lethal neurodevelopmental disorder...

🚨 🚨 NEW PUBLICATION 🚨 🚨 "Vitamin B2 and B3 nutrigenomics reveals a therapy for NAXD disease"

@arcinstitute.org
@ishahjain.bsky.social
@cp-cell.bsky.social

Vitamin B3 Therapy Offers Hope for Fatal Childhood Disease A new framework that matches vitamins with genetic diseases helped uncover that high-dose vitamin B3 can dramatically extend survival in mice with NAXD deficiency.

A new framework that matches vitamins with genetic diseases helped uncover that high-dose vitamin B3 can dramatically extend survival in mice with NAXD deficiency.

@arcinstitute.org
@ishahjain.bsky.social
@cp-cell.bsky.social

Vitamin B2 and B3 nutrigenomics reveals a therapy for NAXD disease A nutrigenomics framework identifies genetic diseases amenable to vitamin B2 and B3 therapies. This approach nominates vitamin B3 as a therapy for NAXD deficiency, a lethal neurodevelopmental disorder...

vitamins!!!! They cure disease! Amazing work (again!) from @ishahjain.bsky.social's lab here at @gladstoneinst.bsky.social (and @arcinstitute.org) www.cell.com/cell/fulltex...

PUMAS Summer Internship Program | Gladstone Institutes PUMAS is Gladstone's flagship internship program designed to support and mentor community college students, providing them with hands-on research experience and a pathway into the sciences.

Each summer, Gladstone welcomes a cohort of community college students to work in a Gladstone lab, alongside a scientific mentor.

Become an integral part of the team and contribute to projects focused on stem cells, machine learning, and other areas central to understanding and treating disease.

YouTube video by Gladstone Institutes From Hiking Trails to the Lab: Discovering New Retrons

Kazuo Nakamura joined Gladstone as a student intern in the lab of @seth-shipman.bsky.social, where he set out to search for retrons—bacterial defense mechanisms that scientists can harness for genome editing.

What began as a teaching project quickly turned into real discovery.

Congrats, Nadia!

RBCs are not passive bystanders in systems metabolism. We had been saying this for years. This time, in collaboration with Isha Jain @gladstoneinst.bsky.social

By the way, the Jain lab is on a roll, with ever more elegant science at each paper. It was a pleasure to collaborate!

Red Blood Cells Soak Up Sugar at High Altitude, Protecting Against Diabetes New study shows red blood cells act as hidden glucose sponges in low-oxygen conditions, explaining why people living at high altitude have lower diabetes rates and pointing toward new treatments.

People living at high altitude have less diabetes. A new study by @gladstoneinst.bsky.social @ishahjain.bsky.social shows why: In low-oxygen conditions, red blood cells soak up sugar from the bloodstream. A drug mimicking this effect reversed high blood sugar in mice.
gladstone.org/news/red-blo...

Join us for the next Infectious Diseases & Human Health Symposium by @gladstoneinst.bsky.social and QBI: "Sex Differences in Immunity and Diseases" on February 27!

Learn more & register: qbi.ucsf.edu/sex-differen...

The challenges scientists face are so complex that they’re nearly impossible to solve without advanced computational tools. #AI helps uncover hidden patterns in massive datasets—patterns that can spark new hypotheses, reveal insights, and even predict what might happen next.

Red blood cells serve as a primary glucose sink to improve glucose tolerance at altitude Martí-Mateos et al. show that red blood cells explain improved glucose tolerance at high altitude. By manipulating red blood cell number, they determine that these cells are necessary and sufficient f...

🚨 NEW PUBLICATION 🚨 "Red blood cells serve as a primary glucose sink to improve glucose tolerance at altitude"

@ishahjain.bsky.social
@dalessandrolab.bsky.social
@medschool.umaryland.edu
@cp-cellmetabolism.bsky.social
@arcinstitute.org

Getting to the heart of atrial cardiomyocyte identity Cardiomyocytes (CMs) of the heart's atria and ventricles have different functions and developmental origins, and common cardiac defects affect each chamber specifically. However, the gene regulatory networks (GRNs) that govern their identities are uncle...

Check out this research highlight in Development spotlighting new work from @irfankathiriya.bsky.social and @benoitbruneau.bsky.social

Gladstone Scientist Nadia Roan Elected to American Academy of Microbiology Roan has made great strides in understanding how persistent viruses including HIV cause disease and how immunity to viruses shapes human health.

Nadia Roan, a pioneer in the fight against some of the world’s most persistent viruses, has been elected as a 2026 Fellow of the American Academy of Microbiology.

Go behind the scenes of an on-screen interview with Gladstone scientist Julia Kaye. Julia studies neurodegenerative diseases like ALS, Parkinson’s, and Huntington’s—and collaborates with researchers across the country to analyze the genomes of thousands of ALS patients.

Red Blood Cells Soak Up Sugar at High Altitude, Protecting Against Diabetes New study shows red blood cells act as hidden glucose sponges in low-oxygen conditions, explaining why people living at high altitude have lower diabetes rates and pointing toward new treatments.

New study shows red blood cells act as hidden glucose sponges in low-oxygen conditions, explaining why people living at high altitude have lower diabetes rates.

@dalessandrolab.bsky.social
@medschool.umaryland.edu
@cp-cellmetabolism.bsky.social
@arcinstitute.org
@ishahjain.bsky.social

Visit our website to learn how scientists are creating new AI tools: gladstone.org/news/how-ai-...

“AI is a transformative force in biomedical research," says Gladstone President Deepak Srivastava.

At Gladstone, researchers are developing new AI platforms that will pave the way to new treatments and medicines for some of the harshest diseases, from Alzheimer’s to cancer to HIV.

Scientists, too, are using AI to better understand how human bodies work and what goes wrong in disease. Yet, the use of AI in science remains a bit of a mystery for the average person.

Artificial intelligence, or AI, is all around: it can draft emails, control your home thermostat, generate videos, and even drive cars.

Artificial intelligence, or AI, is all around: it can draft emails, control your home thermostat, generate videos, and even drive cars.

#AI is transforming science today.

At Gladstone, our researchers are not only using artificial intelligence—they’re building cutting-edge AI platforms that are helping decode disease, uncover new therapeutic targets, and accelerate discoveries that could lead to life-saving treatments.

Meet Gladstone: Alisa Dietl Alisa Dietl brings her international training and clinical perspective to Gladstone, where she works to engineer more effective cancer immunotherapies for solid tumors.

Check out this profile with Gladstone researcher Alisa Dietl (@alisadietl.bsky.social ).

Alisa brings her clinical perspective to Gladstone, where she focuses on how interactions between cancer and immune cells can be targeted to develop more effective cancer immunotherapies.

📣Announcing our first awardees of 2026🌠, who are setting out to uncover new knowledge about microbes in extreme environments, host-microbiome interactions, & bacterial defenses. bit.ly/HFAwardees
Hear why our #HFScouts recommended these talented scientists👇 in our 🧵:

Our scientists aren’t simply using #AI in their work—they're creating some of the world’s most advanced AI models in biomedical research. Their platforms are significantly accelerating the rate of discovery and paving the way to new treatments and cures for diseases ranging from Alzheimer’s to HIV.

Excited about a future in STEM? Applications are open for Gladstone’s 2026 PUMAS Summer Internship Program!

The PUMAS Program is a unique opportunity for community college students to gain real-world experience in biomedical research.

Learn more on our website ➡️ https://bit.ly/2UVIaST

4/ Awardee Sukrit Silas is setting out to solve the longstanding challenge of predicting phage-bacteria compatibility🦠. His project could transform how phages are harnessed to fight against antibiotic resistance.
🍾 Congrats Dr. Silas! @gladstoneinst.bsky.social
#HFScout Devaki Bhaya