Just saw a review about using transcranial NIR (no optogenetics here) to treat Rett syndrome. Excuse my ignorance but apart from suggesting that photons will hit the mitochondria (and more), I see only wishful thinking here. Anyone here to tell if this is real ?

journals.sagepub.com/doi/10.1177/...

Huge congratulations, Nico, on this fantastic work published in Science Signaling! A truly impressive achievement!!!!

Subcellular depletion of importin β1 impairs presynaptic local translation and spatial memory Axonal localization of importin β1 is required for presynaptic functions that support spatial memory tasks.

Very happy to share our new paper in #ScienceSignaling revealing that importin β1 isn’t just important for nuclear transport or neuronal growth.

We now show it is key for presynaptic plasticity in the hippocampus, local translation, and memory!

www.science.org/doi/10.1126/...