Timothy Gottschalk

Tetraspanin CD53 Promotes Inflammation but Restrains Mucus Production in a Mouse Model of Allergic Airway Inflammation Click on the article title to read more.

If you have a minute why not take a look at this study I am very proud to be a part of out today in Allergy, demonstrating how CD53 drives immune cell infiltration and inflammation but controls mucus production in allergic airway asthma-like disease. doi.org/10.1111/all....

Divergent roles of RIPK3 and MLKL in high-fat diet–induced obesity and MAFLD in mice Cell death frequently occurs in the pathogenesis of obesity and metabolic dysfunction–associated fatty liver disease (MAFLD). However, the exact contribution of core cell death machinery to disease ma...

Hi bluesky, just wanted to share our most recent paper from the
@katelawlorlab.bsky.social showing distinct roles for #necroptosis effectors RIPK3 (+ Caspase-8) that drives inflammation, and MLKL which regulates lipid handling in obesity-induced #MAFLD. www.life-science-alliance.org/content/8/1/...