Bertrand Benazeraf

📣Our project, “Mechanometabolic Control of Vertebrate Limb Elongation,” has been funded by Wellcome!
Over the next 8 years, we’ll collaborate with @manningresearch.bsky.social and Nathalie Agar’s group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!🎉

Congratulations Ale :) I am glad to read that!

Show time for paper #2 !!!

And another great gut epithelium story from our cool neighbors !!!😎 @cbitoulouse.bsky.social

Robust pan-junctional reinforcement preserves the gut epithelial barrier under mechanical stress Epithelia are specialized tissue barriers that safeguard the organism's internal milieu from the hostile external environment, a function critically dependent on intercellular junctions. In the colon,...

Ever wondered how adult organs preserve epithelial barrier integrity while continuously exposed to mechanical stress? We tackled this question in our new preprint – led by our brilliant PhD student Vishnu Krishnakumar! (1/11)
🔗 www.biorxiv.org/content/10.1...

Congratulations @mtrani.bsky.social and @campaslab.bsky.social @jesseveenvliet.bsky.social labs !!! Looks great 🤩, impressive measurements !!! Looking forward to digging into it! I am curious: Where is the actin cap located in the mouse embryo, surrounding the whole PSM?

Great news! Congratulations !!!

Dear colleagues, positions at CNRS (and INRIA) will (in all probability) be announced this winter. By then it will however be too late to properly prepare an application. Recent PhDs, postdocs etc interested in such positions should get right now in contact with teams who would like to recruit them.

Preprint alert!
We combined microfluidics, proteomics, and RNA-seq to map spatiotemporal protein expression during mouse somitogenesis and found a novel regulatory strategy: dynamic antagonistic gradients fine-tune signalling strength.

doi.org/10.1101/2025...

#JobOffer

💼 Cell and Molecular Biology Research Engineer (M/F)
📆 November 17th
📍Institut Jacques Monod / @spinalorga.bsky.social

Apply on the CNRS job portal before September 29th 🔗 emploi.cnrs.fr/Offres/CDD/U...

A microscope image showing a developing eye in a quail embryo. Actin is labelled in orange and nuclei are in cyan.

Bird’s eye view, literally. 🐦👁️ Glowing quail embryo eye for #FluorescenceFriday, #DevBio 🧪🔬

Hi bsky!

Do embryonic tissues have backup plans🔀? Gastruloids (model of body elongation) can build an axis through different cellular mechanisms when on adherent substrates instead of free floating. A case of developmental plasticity!

w/ A. Delahaye & ‪@bensteventon.bsky.social‬

shorturl.at/v01DO

An active torque dipole across tissue layers drives avian left-right symmetry breaking Unlike in mice, frogs, and fish, left-right (L/R) body axis formation in avian embryos does not arise from the chiral beat of cilia. Instead, a counter-clockwise tissue rotation around Hensen′ node, t...

(1/10)
I am excited to finally share our work on avian left/right symmetry breaking with you. We reveal a tissue-scale active torque dipole generated at the Hensen’s node, thanks to crazy experiments by Julia @juliapfanzelter.bsky.social and some analysis by me.
doi.org/10.1101/2025...

What started with many quail eggs and put me on stage in a chicken suit has now resulted in a preprint www.biorxiv.org/content/10.1...
Microsurgery with human eye-lashes, laser ablations, great analysis and insightful theory from @neipel.bsky.social told us more about avian L/R symmetry breaking.

Two new preprints from the @arjunraj.bsky.social‬ on #gastruloids. Both excellent. Exploring the relationship between macroscopic reproducibility v microscopic heterogeneity. Stunning experiments and much to think about
biorxiv.org/content/earl...
biorxiv.org/content/earl...

FDA-NIH Workshop: Reducing Animal Testing The FDA is hosting a workshop on reducing animal testing. The workshop is open to current FDA and NIH employees.

Birth defects kill twice as many children as cancer. Animal model are crucial; no stem-cell or computer models can yet recapitulate the embryo's complexity. If you support birth defects research tell NIH that animal models are important! Click & scroll below to comment.

tinyurl.com/mr3he6bx

Research Organisms in Flight: Revealing the Roots of Vertebrate Form… Organized by Tatjana Sauka-Spengler, Ph.D., and Ruth Williams, Ph.D.

12th Avian Model Systems Meeting bit.ly/3ZBw2qS @stowersinstitute.bsky.social. We will be joined by Marianne Bronner, Olivier Pourquié, Megan Davey, Julie Elie, @jeromegros.bsky.social, Carols Lois, Peter Lwigale, Alan Rodrigues, Marcos Simoes-Costa, @melaniedwhite.bsky.social and YOU!

🇫🇷 Nous recrutons un IE en biologie cellulaire, sur un modèle d'étude fascinant : le blob ! N'hésitez pas à partager !
🇬🇧 We are recruiting a research engineer in cell biology, working on an exciting model: the blob! Feel free to share!
👉 emploi.cnrs.fr/Offres/CDD/U...

Great book !

Congratulations! I'm really looking forward to seeing the work that will come out of your lab.

I would like to be added , thanks !

I would like to be added !! Thanks

Enjoying great science and stunning alpine views at the GRC on Cell Contact & Adhesion in Les Diablerets 🇨🇭⛰️ Proud of our PhD students Dhriti and Vishnu for their terrific work - posters and talks full of exciting insights! #CellContactAndAdhesionGRC #CellBiology #PhDLife #LesDiablerets

Great use of the transgenic quail model to answer very basic and important question in developmental biology !

Live imaging and functional characterization of the avian hypoblast redefine the mechanisms of primitive streak induction In birds and mammals, the formation of the primitive streak, the hallmark of the primary axis and site of gastrulation, is thought to occur when an anterior displacement of the hypoblast (visceral end...

🚨New preprint
Glad to share my postdoc work on the role of the hypoblast in primitive streak induction! Discover how live imaging observations led us to revisit the molecular mechanisms governing embryonic axis induction
Thanks to @jeromegros.bsky.social and all co-authors!
doi.org/10.1101/2025...

Great work from Arthur Michaut again ! Very cool study on biophysical properties of the very young avian embryo. Congrats to Arthur, and to the teams of Francis and Jérôme !

This time-lapse captures 17 hours of axonal growth from a chicken dorsal root ganglion explant, visualized through the actin cytoskeleton using live confocal imaging.
I just submitted this video to the Nikon Small World in Motion competition. Today is the last day to upload yours! 😉
🧪

#JobOffer

💼 Ingénieur d’étude (H/F) en cellules souches et biologie cellulaire
📍 @spinalorga.bsky.social Lab
📅 1e juillet 2025
🔗 emploi.cnrs.fr/Offres/CDD/U...

Candidatez avant le 15 mai 2025

Thank you, and congrats on this fascinating preprint! Tissue fluidity and cell sorting are such fundamental and captivating processes!

Congratulations !