Mike Yassa

Mnemonic Similarity Task: A Tool for Assessing Hippocampal Integrity

How do brains manage it? For a long while, the hippocampus has been known to be involved (thanks to @brockkirwan.com, @mikeyassa.bsky.social and others) - eg individuals with hippocampal damage are impaired at tasks like the Brady task.

doi.org/10.1016/j.ti...
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06.12.2025 16:38 — 👍 6    🔁 1    💬 1    📌 0

Landed at #SfN and we have lots of fun new results to share. See below for Yassalab poster presentations. If you want to talk #Alzheimers or #mentalhealth come chat with us.

#SfN25 #neurosky #neuroskyence #academicchatter

15.11.2025 14:45 — 👍 32    🔁 7    💬 0    📌 0

New paper in Imaging Neuroscience by Dana M. Parker, Michael A. Yassa, et al:

NODDI-derived measures of microstructural integrity in medial temporal lobe white matter pathways are associated with Alzheimer’s disease pathology and cognition

doi.org/10.1162/IMAG...

24.10.2025 07:20 — 👍 8    🔁 1    💬 0    📌 0

A Combined Neuroanatomy, Ex Vivo Imaging, and Immunohistochemistry Defined MRI Mask for the Human Paraventricular Nucleus of the Thalamus Existing definitions of the human paraventricular nucleus of the thalamus (PVT) differ between histological and MRI atlases; this study addresses this conflict by leveraging MRI and histology in the ...

Published! to NAIL human paraventricular thalamus, we imaged & aligned postmortem human thalamus labeled c calretinin. Finally a gold standard allowing mouse, rat human comparisons onlinelibrary.wiley.com/doi/10.1002/... @ted-satterthwaite.bsky.social @flagel-lab.bsky.social @mikeyassa.bsky.social l

25.09.2025 16:37 — 👍 11    🔁 5    💬 0    📌 1

Is the brain uncontrollable, like the weather? The brain may be chaotic. Does that mean our efforts to control it are doomed?

Thank you Nicole. I was definitely channeling your thinking as I was writing it. Loved your weather analogy for this. www.thetransmitter.org/the-big-pict...

16.06.2025 20:12 — 👍 1    🔁 0    💬 1    📌 0

Curing Alzheimer’s disease requires a radically different approach. Read my latest piece in @thetransmitter.bsky.social

16.06.2025 14:14 — 👍 9    🔁 2    💬 1    📌 1

He's right. "Nothing short of devastating"
By @holdenthorp.bsky.social @science.org
www.science.org/doi/10.1126/...

05.06.2025 20:41 — 👍 685    🔁 241    💬 12    📌 26

Gary lynch rocking a huge crowd talking about th 50 years of LTP @cnlm.bsky.social @serenadudette.bsky.social @ucirvine.bsky.social
@mikeyassa.bsky.social 🧪🧠 #memory @franklandlab.bsky.social

09.05.2025 22:44 — 👍 11    🔁 3    💬 0    📌 0

UC Irvine CNLM spring meeting fully in session! Celebrating decades of work on synaptic plasticity: From Molecules to Memory @ucirvine.bsky.social

08.05.2025 17:55 — 👍 1    🔁 0    💬 0    📌 0

The brilliant artwork by @neurobatool.bsky.social

06.05.2025 23:13 — 👍 4    🔁 0    💬 0    📌 0

Confessions of a Reformed DEI Officer (opinion) We need to distinguish between good DEI and bad DEI, Michael A. Yassa writes.

DEI is under fire… but may be we need something better. I spent five years as a diversity officer in academia and this is what I’ve learned. Read my take at @insidehighered.com www.insidehighered.com/opinion/view...

06.05.2025 22:22 — 👍 6    🔁 1    💬 0    📌 0

Ecstatic to receive my PhD today!! So incredibly thankful to my PI @mikeyassa.bsky.social for all his encouragement in growing my scientific career and endeavors. Also thankful to family, friends, and other mentors/collaborators! 😍🧠🎉
@elizabethhead.bsky.social
@chrastil.bsky.social

07.12.2024 04:56 — 👍 49    🔁 4    💬 10    📌 1