New paper out in PRL!
With @artemyte.bsky.social and Sosuke Ito, we combine stochastic thermodynamics with nonequilibrium MaxEnt in large networks to infer entropy dissipation in high-dimensional systems from time series (up to 1000 variables!)
journals.aps.org/prl/abstract...
By capturing the balance between aggregate formation and cellular clearance, our model explains decades of stability before sudden runaway dynamics, and offers a framework to predict disease onset and therapeutic efficacy. Mostly driven by Matthew Cotton and Georg Meisl doi.org/10.1063/5.03...
19.02.2026 09:01 — 👍 7 🔁 3 💬 0 📌 0
🚨PREPRINT
In our new paper, we link RNNs and neural manifolds by introducing the DDM framework.
We can train networks to embed an arbitary dynamical system in a latent subspace. We illustrate this with simple models of input-driven and autonomous associative memory. Enjoy!
arxiv.org/abs/2602.14885
Job alert🚨I am advertising a 2-year postdoctoral position to work on the mathematics of plant morphogenesis @mpipz.bsky.social. Candidates with interests in mathematical modelling, mechanics, or biophysics are strongly encouraged to apply. 🌱Reposts are appreciated!
jobs.mpipz.mpg.de/jobposting/4...
❗🧠 New review in IEEE RBME
How network math models are reshaping how we think about neurodegenerative disease, from brain dynamics to disease progression
"Network models of neurodegeneration: bridging neuronal dynamics and disease progression"
ieeexplore.ieee.org/document/113...
O little town of Oxford,
How still we see thee lie.
But above thy deep and dreamless sleep,
Complex thoughts go by.
Still not convinced? Don't worry, you have all Christmas to 'mull' it over. Closes 12 January.
Full details of the role: www.maths.ox.ac.uk/node/74844
This week, the work we did as part of my research internship at IBM is being presented at the MLxOR workshop at NeurIPS.
We look at uncertainty quantification for GFlowNets using PCEs.
See the poster below:
This new #JRSocInterface Perspective, using #neuroscience as an example, argues for a new paradigm of holistic #mathematical modelling that attempts to incorporate the necessary complexity into models of biological systems: royalsocietypublishing.org/doi/10.1098/... @rnartallo.bsky.social
27.11.2025 17:00 — 👍 5 🔁 3 💬 0 📌 0
🚨Our perspective article of the future of mathematical modelling for complex biological systems has been published in Interface.
royalsocietypublishing.org/doi/10.1098/...
I hope you enjoy it :)
🚨PREPRINT
Coarse-graining diffusions with discrete-state approximations is an easy and effective way to build stochastic models from observed trajectories, but how valid is this approximation?
arxiv.org/pdf/2511.05366
We focus on this problem, with an emphasis on the nonequilibrium steady-state.
My work on uncertainty quantification for GFlowNets, that I did during my research internship at IBM is now out on the arXiv!
arxiv.org/pdf/2510.215...
Our review paper on nonequilibrium physics in the brain is now out in Physics Reports!
doi.org/10.1016/j.ph...
How does the 🧠 process information?
In this review we show how to use the tools of non-equilibrium thermodynamics to understand brain dynamics in discrete and continuous state spaces
Great work led by Ramon as part of his PhD
kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
Last week I gave the ECM Seminar at the
@ima-maths.bsky.social on 'Time's Arrow - Life and Mind out of Equilibrium'.
You can now rewatch the seminar online:
www.youtube.com/watch?v=hXBo...
⭐New preprint: "A multiscale theory for network advection-reaction-diffusion"
with @alaingoriely.bsky.social and Emilia Cozzolino
arxiv.org/abs/2509.06546
This month's @londmathsoc.bsky.social newsletter contains a feature by one of the world's greates living scientists (me)
and also work by Roger Penrose.
I hope you enjoy :)
www.lms.ac.uk/sites/defaul...
Excited to say that I will giving the IMA Early Career Mathematicians seminar on October 9th.
ima.org.uk/27052/ecm-se...
It will be happening online so feel free to join!
I will talking about nonequilibrium steady-states in complex systems - what they are and how to find them
Oxford Mathematician @alaingoriely.bsky.social awarded the 2025 LMS/IMA David Crighton Medal for his deep and influential insights into mechanical and biological processes, support of early career mathematicians, and commitment to the public understanding of maths.
www.maths.ox.ac.uk/node/72714
Our paper just out in Nature Communications!
www.nature.com/articles/s41...
We introduce curved neural networks naturally introducing high-order interactions showing:
• explosive phase transitions
• enhanced memory retrieval via self-annealing
• increased memory capacity through geometric curvature
This year’s Workshop on Stochastic Thermodynamics (WOST VI) talks are now online!
I was very grateful to give a short talk about my work on nonequilibrium brain network dynamics:
youtu.be/-z38f0fVMs4?...
Today, the Tour de France begins 3 gruelling weeks of sun, scenery & summits, but what's the key to winning in this elite world of small margins? How about appetite for risk? @imgoxford.bsky.social & @javichico.bsky.social lead the breakaway.
Read more: www.maths.ox.ac.uk/node/72427
#TDF2025
Tremendously proud of my dear friend Romain Guyon who has just published this amazing paper on the cover of Science Translational Medicine!
He has invented revolutionary new technology for the delivery of booster vaccine doses in a single shot.
www.science.org/doi/10.1126/...
Final shift at @netsciconf.bsky.social presenting my poster on nonequilibrium brain network dynamics.
Also got to see our fearless leader, Renaud Lambiotte, collect his well-deserved Fellowship.
#NetSci2025
Speaking at NetSci2025 about our recent Learning on Graphs paper.
We build up a theoretical and applied approach to use Hodge theory on graphs to study stochastic systems!
arxiv.org/pdf/2409.07479
#NetSci2025
You won't believe your eyes!
02.06.2025 12:27 — 👍 7 🔁 1 💬 0 📌 0
I posted about this paper this a while ago on another website, but figured I'd post it here now that I have a few followers. (Joint with @haharrington.bsky.social, Jacob Leygonie, @uzulim.bsky.social, and Louis Theran).
arxiv.org/abs/2411.08201
1/10
Me and Leonardo recently sat down to talk to Dyrol about our recent project, and more generally about collaboration in the mathematical and applied sciences. We hope you enjoy!
You can read the paper here: www.pnas.org/doi/abs/10.1...
Or the case study on the Maths site
www.maths.ox.ac.uk/node/70955
Last week, I gave the Networks seminar here at Oxford on:
'Nonequilibrium steady-states: from diffusion to digraphs',
talking about some of my recent work on discrete approximations of nonequilibrium diffusions. It is available online:
www.youtube.com/watch?v=ezep...
:)
🚨REVIEW
We have written a review on the emerging topic of nonequilibrium, irreversible dynamics in the brain.
Now out on the arXiv: arxiv.org/abs/2504.12188
We introduce the relevant mathematical frameworks, discuss recent interesting results, and look to the future of this research direction!
