UC Davis Center for Neuroscience

The psychoplastogen tabernanthalog induces neuroplasticity without proximate immediate early gene activation - Nature Neuroscience Aarrestad et al. show that, in contrast to psychedelics, the nonhallucinogenic psychoplastogen tabernanthalog promotes neuroplasticity through 5-HT2AR activation without immediately increasing extrace...

The field of psychedelic science is finally closer to an answer on how non-hallucinogenic psychedelic analogues induce neuroplasticity.  Read the new publication from the #UCDavisIPN in @natureportfolio.nature.com Neuroscience about how the team uncovered this using TBG, lasers, and genetic tools.

04.08.2025 15:21 — 👍 7    🔁 3    💬 0    📌 1

Super cool to see this replayed! @nprfreshair.bsky.social

20.06.2025 10:39 — 👍 7    🔁 2    💬 0    📌 0

The keynote presentation of #TAMeG2025 10th Anniversary 🌟 was by Dr. Charan Ranganath on “Why (and how) we remember🧠 Thank you Dr. Ranganath for an *incredible* presentation on the organization of narrative recall @charan-neuro.bsky.social @brianlevine.bsky.social

🔑 takeaways below⬇️

28.05.2025 00:54 — 👍 8    🔁 3    💬 1    📌 1

Six young adults stand in a line outdoors, smiling in casual attire, with trees and sunlight in the background.

Congratulations to the 2025–2026 NIMH 𝗟𝗮𝗠𝗣 T32 trainees @ucdavis.bsky.social! 🎉

Nam Nguyen (Boorman Lab)
Stephanie Norris (Yonelinas Lab)
Teresina Berni (DeBello Lab)
Zachary Oakland (Trainor Lab)
Alessandra Miller (Gareau Lab)
Ruben Berumen (Hell Lab)

Excited to see the amazing science ahead! 🧠🔬

15.05.2025 18:59 — 👍 16    🔁 3    💬 0    📌 0

🧠✨Congratulations to the awesome undergraduates who work in CNS labs and showcased their research at the 𝟯𝟲𝘁𝗵 𝗔𝗻𝗻𝘂𝗮𝗹 𝗨𝗻𝗱𝗲𝗿𝗴𝗿𝗮𝗱𝘂𝗮𝘁𝗲 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵, 𝗦𝗰𝗵𝗼𝗹𝗮𝗿𝘀𝗵𝗶𝗽 𝗮𝗻𝗱 𝗖𝗿𝗲𝗮𝘁𝗶𝘃𝗲 𝗔𝗰𝘁𝗶𝘃𝗶𝘁𝗶𝗲𝘀 𝗖𝗼𝗻𝗳𝗲𝗿𝗲𝗻𝗰𝗲.

We are incredibly proud of their hard work and curiosity — the future of neuroscience is bright!! 🧬🔬

28.04.2025 18:52 — 👍 10    🔁 0    💬 0    📌 0

Modifying LSD to Minimize Hallucinogenic Properties Results in a Potential New Drug Candidate for Schizophrenia | Brain & Behavior Research Foundation Some psychedelic compounds have been shown to be powerful promoters of growth in atrophied cortical neurons, a fact that has intrigued researchers interested in addressing one of the hallmark patholog...

Check out this write-up on JRT, an LSD analogue created at the #UCDavisIPN published last week in @pnas.org. Thanks to BBRF for highlighting our research on how swapping just two atoms could change how schizophrenia is treated. Read more about our latest study here:

24.04.2025 22:43 — 👍 4    🔁 1    💬 0    📌 0

From Labs to Lives UC Davis researchers describe the impact of their work and the life-altering consequences if federal funding for medical research were reduced or eliminated.

www.ucdavis.edu/research/lab...
@ucdavis.bsky.social
@ucdavishealth.bsky.social
@ucdavisplants.bsky.social
@ucdaviscns.bsky.social
@ucdavispsych.bsky.social

19.04.2025 16:51 — 👍 6    🔁 2    💬 0    📌 0

Thank you, Greg Watry, for this write-up on JRT, our non-hallucinogenic LSD analog from the #UCDavisIPN. This compound has the potential to treat patients affected by schizophrenia! @ucdavismedschool.bsky.social @ucdlands.bsky.social @ucdaviscns.bsky.social

15.04.2025 15:38 — 👍 6    🔁 2    💬 0    📌 0

Dynamic Memory Lab_Jr Specialist_Ranganath University of California, Davis is hiring. Apply now!

I'm looking for a new full-time research assistant ("junior specialist"). It's not quite "lab manager" because I have someone who takes care of the administrative tasks, and here I'm looking for someone to help us get research done! Info is below, please pass on to any talented candidates, thanks!

08.04.2025 23:29 — 👍 56    🔁 63    💬 2    📌 1

The Oehrn Lab @carinaoehrn.bsky.social at CNS is hiring two postdocs in human intracranial neurophysiology and neuromodulation—studying cognitive and emotional processing in the cerebellum and basal ganglia. Learn more: oehrnlab.ucdavis.edu/open-positions

28.03.2025 13:40 — 👍 3    🔁 0    💬 0    📌 1

What’s at stake if federal #NIH research funding is cut? Here’s just one example of a life-changing breakthrough made possible by NIH grants. Tell Congress to #saveNIHresearch at ucal.us/saveNIHresearch

#ALS #stroke @ucdavis.bsky.social @ucdavishealth.bsky.social

13.03.2025 22:00 — 👍 49    🔁 18    💬 0    📌 1

Flyer for NeuroFest 10th Anniversary event hosted by the UC Davis Center for Neuroscience. The flyer features a digital brain design made of golden circuit lines against a dark background with molecular and neural network patterns. Event details: Saturday, March 8, 12:30 PM – 4:30 PM at UC Davis Conference Center, 550 Alumni Lane. Space is limited; registration deadline is February 28. Website: neuroscience.ucdavis.edu/neurofest.

Join us @ucdavis.bsky.social on March 8 for the 10th anniversary of NeuroFest, featuring talks by Drs. Alex Nord, Martine Therrien, Jochen Ditterich and Carina Oehrn;
interactive booths; NeuroArt Contest 2025; and NeuroPoster presentations by trainees! Learn more: neuroscience.ucdavis.edu/neurofest

10.02.2025 19:56 — 👍 3    🔁 1    💬 0    📌 0

Flyer for NeuroFest 10th Anniversary event hosted by the UC Davis Center for Neuroscience. The flyer features a digital brain design made of golden circuit lines against a dark background with molecular and neural network patterns. Event details: Saturday, March 8, 12:30 PM – 4:30 PM at UC Davis Conference Center, 550 Alumni Lane. Space is limited; registration deadline is February 28. Website: neuroscience.ucdavis.edu/neurofest.

Join us @ucdavis.bsky.social on March 8 for the 10th anniversary of NeuroFest, featuring talks by Drs. Alex Nord, Martine Therrien, Jochen Ditterich and Carina Oehrn;
interactive booths; NeuroArt Contest 2025; and NeuroPoster presentations by trainees! Learn more: neuroscience.ucdavis.edu/neurofest

10.02.2025 19:56 — 👍 3    🔁 1    💬 0    📌 0

How memories are transferred between brain regions during consolidation How are memories transformed and moved over time between brain regions? We propose a simple organizing principle for how long-term memories are moved from an initial to a final site of storage, a process known as "memory consolidation." We show that successful transfer occurs when the late site of memory storage is endowed with synaptic plasticity rules that stably accumulate changes in activity occurring at the early site of memory storage. We instantiate this principle in a simple computational model that is representative of brain circuits underlying a variety of behaviors. The model suggests how a neural circuit can store new memories while preserving core features of older ones and proposes functional roles for core elements of the cerebellar circuit.

How are memories transformed and moved over time between brain regions? Read paper in @pnas.org by Brandon J. Bhasin, Dr. Jennifer L. Raymond & Dr. Mark S. Goldman. Stanford Wu Tsai Neuroscience Institute @stanford.edu & UC Davis Center for Neuroscience collaboration.: link.growkudos.com/1ozs0mh0av4

03.02.2025 20:49 — 👍 6    🔁 1    💬 0    📌 0

Frontiers | Abnormal c-Fos expression in TetTag mice containing fos-EGFP

If you're using TetTag mice to label "engram cells" you might be interested in our recent paper. We discovered an issue with a popular strain from Jackson that contains fos-shEGFP. Endogenous levels of c-Fos expression appear to be massively increased when performing IHC.

doi.org/10.3389/fnbe...

18.12.2024 19:07 — 👍 6    🔁 1    💬 0    📌 0

Recurrent Inhibitory Dynamics in the Entorhinal Cortex Support Pattern Separation The entorhinal cortex (EC) provides the major input to the hippocampus (HPC). Numerous computational models on the EC propose that its grid cells serve as a spatial metric, supporting path integration...

Super-psyched to share this preprint from my student Yicong (Alan) Zheng: "Recurrent Inhibitory Dynamics in the Entorhinal Cortex Support Pattern Separation" www.biorxiv.org/content/10.1... It's a new biologicaly-based computational model of the entorhinal-hippocampal system. Thread (1/?)

18.11.2024 22:46 — 👍 79    🔁 26    💬 3    📌 1