Dr. Fiona

jesus fucking christ

.... should i do another best amino acid but on bluesky??? i dont have as many followers here on bluesky though so it might not get hyped as much

Silvia's simulations showed that while all epitopes expose Sia for binding, Siglec-6 recognises and binds only GM1 because of a key interaction with the membrane through W127 and K126, which orientates the V-set domain to bind the Sia through Arg122 and the terminal Gal to the C-C' loop 😎

Wee thread 🧵⬇️ on our new #glycotime with @siglecdude.bsky.social John Klassen and @glycocode.bsky.social 🥳 where we show Siglecs as molecular precision tools, able to recognise sialylated glycans with surgical precision in their natural environment, not bad for a lectin! 😎

doi.org/10.1038/s420...

"FIFA Peace Prize – Football Unites the World" 👍🏼

its crazy how evil these people look juxtaposed next to the word peace

The Minneapolis Trials has a nice ring to it.

To be clear: I believe everyone in this video should be held on trial for Treason and violating the Constitution. I suggest Minneapolis MN as the ideal site for said trial.

I just wish Virginia Giuffre was here to see Andrew Mountbatton-whateverthehell in handcuffs

lets see how well his "i cant sweat" defense holds up in court

Sucks to live in the era of a lot of people learning that it takes a lot less time and effort to destroy stuff than to build (or re-build) it.

UK: Prince Andrew arrested.

South Korea: Former President Yoon sentenced for life.

Brazil: Former President Bolsonaro serving a 27-year sentence.

USA: President Trump demands $10 billion payout from taxpayers.

this tops the list for completely unsurprising headlines.

Tweet from Former President Barack Obama which reads "I was trying to stick with the spirit of the speed round, but since its gotten attention let me clarify. Statistically, the universe is so vast that the odds are good that there's life out there. But the distances between solar systems are so great that the chances we've been visited by aliens is love, and I saw no evidence during my presidency that extraterrestrials have made contact with us. Really!"

Screenshot of a quote from Trump which reads "China was going to hit us with rare-earth. Now, everybody says, “Oh, what does that mean?” Magnets. If China refused to give magnets, ’cause they have a monopoly on magnets ’cause they’re allowed to happen over a 32-year period, there wouldn’t be a car made in the entire world. There wouldn’t be a radio. There wouldn’t be a television. There wouldn’t be internet. There wouldn’t be anything because magnets are such a part. Now, nobody knows what magnets are. And not overly sophisticated, but to build magnet system would take two years. So if I weren’t able to say to China, “Look, if you’re gonna do that to us, we’re gonna charge you a 158% tariff.” It was 100% on top of 58%. And China called up immediately and, “Listen, we will make peace.” And we made peace. We made a great deal. We made an unbelievable deal. China’s paying tariffs to the United States. Not the United States paying tariffs to China, which has always been the way it was. Nobody can believe these deals."

I miss having an articulate president.

My heights have officially been wuthered.

Absolutely phenomenal and beautiful rendition of the classic novel, in my opinion, I think the tone of classism was exceptionally clear, the racism was missing (if not inverted) but overall the tortured love plot was powerful.

My family still keeps a "Help Wanted. No Irish Need Apply" sign hung in our house

so M*sk can take this racist dog whistle and shove it right up where the sun dont shine.

Cutaway and close-up views of a Martini coarse-grained whole-cell model of JCVI-syn3A, showing the densely packed cytoplasm with proteins, RNA, metabolites, and chromosome inside a lipid membrane with embedded membrane proteins

Our paper on [Bentopy](doi.org/10.1002/pro....) is out in Protein Science! We developed Bentopy to make assembling large-scale MD models more accessible, building on what we learned from trying to simulate whole-cell models. Here's our updated Martini JCVI-syn3A cell model👇

OMFG!~!!!!!!

GENAU.

i mean isnt morning joe on msnbc? i cant imagine msnbc would have an ice ad thats insane?! or is it not on msnbc anymore?

Continually absolutely disgusted with the many ways in which this administration is actively and directly harming children. Party of "family values" my ass.

SAVE Act:
Asks for naturalization papers which US birth citizens do not have.
Or
REAL ID which requires your last name match that of your birth certificate, which disqualifies married women who are US citizens.
Or
passport which poor rural Americans usually don’t have.

SAVE Act is anti American

what will i do with all the random 4 letter codes i have stuck in my head?!

Do you love building AI/ML models across a wide range of research topics? TU Wien is hiring two senior scientists/postdocs for a university-wide AI/ML service center (www.tuwien.at/datatudiscovery).

Computer science: jobs.tuwien.ac.at/Job/263874
Science/engineering: jobs.tuwien.ac.at/Job/263875

on msnbc!?

onion honestly might just have to shut themselves down

oh? was it the lack of mention of blue jeans, beer, pickup trucks? or maybe they didnt like being directly confronted with the many was in which the US has mistreated PR (and hawaii)? or maybe they just didnt like that it was in spanish?

On my way to Aachen for the 5th German workshop on structural predictions of membrane proteins: from ion channels to G protein-coupled receptors.
I will talk about drug transporters and Toll-like receptors tomorrow.
#compchem

YouTube video by NFL Bad Bunny's Apple Music Super Bowl Halftime Show

This made me cry! What a powerful show!
youtu.be/G6FuWd4wNd8?...