SPMIR Group 🧫🌿🔬 spmir

How does molecular valency shape condensate assembly and function? We used the CO2-fixing organelle in algae—the pyrenoid—to find out… 🧵

Preprint here!:
www.biorxiv.org/content/10.6...

@cellarchlab.com @phaips.vd.st @biologyatyork.bsky.social
#Rubisco #PhaseSeparation #Condensates #Pyrenoid

30.01.2026 15:20 — 👍 78 🔁 37 💬 1 📌 5

ONE WEEK to the deadline! #PlantSciJobs #phd #plantsciphd email me jo.a.hepworth@durham.ac.uk for more information (I'm friendly and keen to meet you!) and tips on application documents. www.needl.org.uk

20.02.2026 21:57 — 👍 7 🔁 10 💬 0 📌 0

Happy New Year from the SPMIR Group. The image shows an illustration of our research topics.

Happy New Year from the SPMIR Group! May this year bring you health, joy, and success.

04.01.2026 19:38 — 👍 11 🔁 3 💬 0 📌 0

The image displays fluorescent bacteria organized into a heart-shaped structure.

The SPMIR group wishes you a lovely end of 2025 and a happy New Year 2026! May the coming year be full of success and joy for all of you 🥂

21.12.2025 11:19 — 👍 7 🔁 2 💬 1 📌 0

It is an illustration of some of our plant transgenic lines imaged during the optimization of our protocol.

Optimizing our plant imaging protocol and having fun along the way 😜

23.11.2025 15:54 — 👍 8 🔁 1 💬 0 📌 0

GitHub - victorgcb1987/GAQET2 Contribute to victorgcb1987/GAQET2 development by creating an account on GitHub.

We have done our first @protocolsio.bsky.social. Are you interested about #genome_annotation quality evaluation? We have developed a tool called #GAQET2 (github.com/victorgcb198...) which runs several tools like #AGAT, #BUSCO, and many other tools. You can find it at www.protocols.io/view/structu...

18.11.2025 14:52 — 👍 12 🔁 6 💬 1 📌 0

Bethel at the 2025 colloquium of the Association Femmes et Sciences

Bethel Dereje attended with curiosity the 2025 colloquium of the Association Femmes et sciences. This organization that advocates for gender equality in science from preschool all the way to higher education. What an inspiring picture of a talented young scientist full of enthusiasm 🥰

16.11.2025 10:46 — 👍 6 🔁 1 💬 0 📌 0

Fluorophore-based Genetically Encoded Biosensors for Ratiometric Fluorescence Imaging in Microbes Investigating small-molecule dynamics within microbes is essential for comprehensive studies of microbial function. Both intra-organism and inter-organism small molecule dynamics play critical roles in microbial physiology, symbiosis, and disease. However, monitoring these dynamics remains highly challenging using most existing techniques. Fluorophore-based genetically encoded biosensors are powerful tools for tracking small-molecule dynamics in vivo and hold high potential for driving new discoveries. These biosensors are most commonly used in fluorescence imaging, often in combination with perfusion devices that allow precise control over environmental conditions. When integrated with advanced imaging techniques, this approach provides high-resolution, spatially and temporally resolved data, enabling insights into single-cell microbial responses. Despite their promise, implementing such biosensors remains technically challenging. Understanding the key steps is crucial for broader adoption. Here, we present a protocol designed to support the effective deployment of newly engineered biosensors into microbes for quantitative ratiometric fluorescence imaging under controlled conditions.

Our new protocol paper is out in JoVE.
“Fluorophore-based Genetically Encoded Biosensors for Ratiometric Fluorescence Imaging in Microbes”
Open access link: udl.hal.science/hal-05206336/

17.10.2025 04:39 — 👍 7 🔁 3 💬 0 📌 0

The pictures show the setup of our research group.

We are currently (re)building ourselves…and making pictures for memories 😉 #NewTeam #NewPI

02.11.2025 11:26 — 👍 6 🔁 2 💬 0 📌 0

The pictures show the setup of our research group.

We are currently (re)building ourselves…and making pictures for memories 😉 #NewTeam #NewPI

02.11.2025 11:26 — 👍 6 🔁 2 💬 0 📌 0

🌱🧪 So thrilled to have contributed to this manifesto for #PlantScience #Education, published in @plantspeopleplanet.bsky.social, and instigated by the visionary and enthusiastic @katharinehubbard.bsky.social and co-led by @apaterlini.bsky.social and @lizalvey.bsky.social 🧶 1/3

29.10.2025 22:56 — 👍 14 🔁 6 💬 2 📌 0

I am thrilled to share the peer reviewed version of our work on how the circadian clock gates In11-induced responses to tightly regulate induced antiherbivore responses in legumes. onlinelibrary.wiley.com/doi/10.1111/pc…

23.10.2025 21:18 — 👍 2 🔁 1 💬 0 📌 0

A worm among bacterial stars ✨️🪱

My picture of bacterial-nematode symbiosis made the cover of AEM with my first thesis paper !!

journals.asm.org/doi/10.1128/...

#SymbioSky

22.10.2025 15:56 — 👍 11 🔁 4 💬 1 📌 0

SPT of DNA repair proteins after cell irradiation by Ashli Kobayashi @asaki-kobayashi.bsky.social and Romane Riou. Setup by Abbelight @abbelight.bsky.social and irradiator by Errol Laser @errol-laser.bsky.social. Look at that recruitment!
#Mifobio2025 @gdrimabio.bsky.social

13.10.2025 14:32 — 👍 15 🔁 6 💬 0 📌 1

Fluorophore-based Genetically Encoded Biosensors for Ratiometric Fluorescence Imaging in Microbes Investigating small-molecule dynamics within microbes is essential for comprehensive studies of microbial function. Both intra-organism and inter-organism small molecule dynamics play critical roles in microbial physiology, symbiosis, and disease. However, monitoring these dynamics remains highly challenging using most existing techniques. Fluorophore-based genetically encoded biosensors are powerful tools for tracking small-molecule dynamics in vivo and hold high potential for driving new discoveries. These biosensors are most commonly used in fluorescence imaging, often in combination with perfusion devices that allow precise control over environmental conditions. When integrated with advanced imaging techniques, this approach provides high-resolution, spatially and temporally resolved data, enabling insights into single-cell microbial responses. Despite their promise, implementing such biosensors remains technically challenging. Understanding the key steps is crucial for broader adoption. Here, we present a protocol designed to support the effective deployment of newly engineered biosensors into microbes for quantitative ratiometric fluorescence imaging under controlled conditions.

Our new protocol paper is out in JoVE.
“Fluorophore-based Genetically Encoded Biosensors for Ratiometric Fluorescence Imaging in Microbes”
Open access link: udl.hal.science/hal-05206336/

17.10.2025 04:39 — 👍 7 🔁 3 💬 0 📌 0

🤯

15.10.2025 12:07 — 👍 5 🔁 3 💬 0 📌 0

SPMIR preview website

Welcome to Théo Perche 🎉 who will be joining us as PhD candidate!
To learn more about Théo, check out 👉 spmir-group.academicwebsite.com/people @spmir.bsky.social
Wishing you the best possible start, Théo 🌟 I’m looking forward to collaborating with you 🤝✨
#PhD #Research #Collaboration #Teamwork

28.09.2025 10:45 — 👍 9 🔁 2 💬 0 📌 0

SPMIR Group Preview Page

Welcome to Bethel Tadesse 🎉 who will be joining us as an Assistant Engineer 🔧✨
Learn more about Bethel here 👉 spmir-group.academicwebsite.com/people @spmir.bsky.social
Wishing you a wonderful start, Bethel 🌟 I’m excited to tackle new challenges together🤝🚀
#Engineering #Research #Teamwork

28.09.2025 10:47 — 👍 7 🔁 2 💬 0 📌 0

Posts by SPMIR Group 🧫🌿🔬 (@spmir.bsky.social)