Enrique de-Madaria's Avatar

Enrique de-Madaria

@demadaria.bsky.social

Passionate about clinical research. Gastroenterologist, pancreatologist. Alicante, Spain

669 Followers  |  895 Following  |  62 Posts  |  Joined: 20.11.2024  |  1.9857

Latest posts by demadaria.bsky.social on Bluesky

Preview
He is still there, in Brazil Γ‰l aun estΓ‘ allΓ­, en Brasil

Don't miss the latest entry on my blog

He is still there, in Brazil

How a French doctor influenced several generations of Brazilian colleagues

demadaria.substack.com/p/he-is-stil...

30.11.2025 09:06 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
9 years in 7 minutes 9 aΓ±os en 7 minutos

9 years in 7 minutes

How does it feel when, after 9 years of work, a clinical trial like SIMBA is presented for 7 minutes at a conference?
#UEGweek #Berlin

Don't miss the latest post on my blog #DeMadariaVsPlacebo

demadaria.substack.com/p/9-years-in...

12.10.2025 07:01 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
ein Mann mit verschrΓ€nkten Armen

ein Mann mit verschrΓ€nkten Armen

eine Gruppe von Menschen steht in einem Flur

eine Gruppe von Menschen steht in einem Flur

Congratulations to our newly elected council members:

Silvio Danese, Vice President
@iagorlago.bsky.social​, Chair Elect Education Committee

ChloΓ© Melchior, Research Committee Chair
@demadaria.bsky.social​​, Independent Councillor

We are looking forward to working with you! ​

04.10.2025 16:45 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Preview
The Difficult Decision of the Daruma’s Eye La difΓ­cil decisiΓ³n del ojo del Daruma

Don't miss the latest post on my clinical research blog #DeMadariaVsPlacebo

The Difficult Decision of the Daruma's Eye

When you have to decide which exciting project to focus on

demadaria.substack.com/p/the-diffic...

14.09.2025 05:56 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Post image

Best of @myueg.bsky.social session during the Panamerican Gastroenterology week in Lima, Peru #SPED2025 @maloehr.bsky.social

31.08.2025 15:45 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 1    πŸ“Œ 1
Preview
How to make your collaborative clinical study fail Como conseguir que tu estudio clΓ­nico colaborativo fracase

Don't miss the new post on my blog DeMadaria Vs Placebo.

Following the success of How to Get Your Article Rejected and 10 Tricks to Be a Terrible Mentor, here comes How to Fail in Your Collaborative Study.

demadaria.substack.com/p/how-to-mak...

10.08.2025 07:34 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Should GI bleeding/altered mental status be considered organ failure in acute pancreatitis? Pancreatology

Our latest publication: This study evaluates the independent associations of GIB and IMS with morbidity and mortality in AP

authors.elsevier.com/a/1lYrs53tct...

07.08.2025 08:12 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Bring Harvard to your CV! Last days for early bird registration Lleva a Harvard a tu CV

Final days for Early Bird Registration!

Join the Harvard postgraduate course on pancreatic diseases and bring Harvard to your CV

Learn the best and discover brand-new lectures not included in previous editions

open.substack.com/pub/demadari...

03.08.2025 08:58 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Bile from polar bears La bilis de los osos polares

There is a drug called ursodeoxycholic acid that dissolves gallstones. Urso means β€œbear” in Latin. Why is it called that?

Why does our OSOPOLAR (POLAR BEAR) clinical trial have that name?

Read my latest blog post
πŸ‘‡πŸ»πŸ‘‡πŸ»πŸ‘‡πŸ»
demadaria.substack.com/p/bile-from-...

27.07.2025 07:46 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Nice abdominal X-ray

06.06.2025 18:28 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

πŸ₯³πŸ‘‰Very happy to share our latest paper published in Endoscopy

πŸ™ŒGreat team effort from 17 πŸ‡ͺπŸ‡Ίcenters

PPI πŸ’Š intake lead to ↗️ LAMS occlusion and ↗️ necrosectomy rates addressing WONs but 🩸complication same as No PPI

What is your practice?

tinyurl.com/2ubsu5u4

10.05.2025 21:06 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 1    πŸ“Œ 2
Post image

I particularly love the corn-pancreas

04.05.2025 07:52 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
How and when do we become infected with Helicobacter pylori? H. pylori: The Most Common Chronic Infection in Humans β€” But How Do We Catch It?

How and when do we become infected with Helicobacter pylori?

From my blog for patients "The Pitch of The Stomach"

thepitofthestomach.substack.com/p/how-and-wh...

04.05.2025 06:51 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
Preview
How to Survive and Succeed in the Design and Execution of a Collaborative Randomized Controlled Trial This article guides the design and execution of successful collaborative randomized controlled trials (RCTs). Aimed at researchers looking to impact clinical practice, it highlights the advantages of....

Just published in @UEGJournal : β€œHow to Survive and Succeed in the Design and Execution of a Collaborative Randomized Controlled Trial”

There you have all the tricks I've learned over the last 15 years about how to conduct a multicenter RCT

All🦾

onlinelibrary.wiley.com/doi/10.1002/...

27.04.2025 09:18 β€” πŸ‘ 8    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

3/3
This is a very special study for me, as I received the @myueg.bsky.social Research Prize for this project.

Many thanks to all the contributors who have worked so efficiently and passionately!

24.04.2025 14:21 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

2/3
With a total of 792 patients from 43 centers across 18 countries from the 5 continents were included in the WATERLAND trial, making it the largest and most globally representative randomized clinical trial conducted in acute pancreatitis to date.

24.04.2025 14:21 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Post image

1/3
The abstract with the results of WATERLAND, an RCT comparing lactated Ringer's solution vs. normal saline in fluid therapy for acute pancreatitis, has just been submitted to the UEG Week Berlin October 25 @myueg.bsky.social

24.04.2025 14:20 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

3/3

We have worked hard on this new edition, we will deal with new topics on September 26th and 27th, all online and with 3 months to watch the talks, soon we will give you more information.

18.04.2025 18:27 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

2/3

The first edition was a success, almost 500 people registered from 50 countries, with talks by 34 international experts in pancreatology with the aim of improving your clinical practice

18.04.2025 18:26 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Post image Post image

1/3

Very good news: the second edition of the course "Management of Pancreatic Disorders for the Practicing Clinician" co-directed by Yasmin Hernandez-Barco and myself has just been approved by @harvard.edu

18.04.2025 18:25 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Preview
Direct Stimulation of Gastric Smooth Muscle Cells via Gq Proteins With Light Optogenetic stimulation enables direct and selective stimulation of smooth muscle cells and thus provides a new opportunity to restore gastric contractility in cases of gastroparesis. Herein, we demo...

ΒΏSerΓ‘ iluminar el estΓ³mago una buena estrategia para tratar la gastroparesia?
Resumimos los resultados de un estudio al respecto y su traslaciΓ³n a la prΓ‘ctica clΓ­nica
πŸ‘‡πŸ‘‡πŸ‘‡πŸ‘‡
doi.org/10.1111/nmo....

14.04.2025 17:12 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
Post image Post image Post image

Participating in Chronicity Forlì 2025 invited by my friend Carlo Fabbri #EmiliaRomagna

Great talks on promotion of research, basic research in pancreatic cancer.

Sharing a nice experience with Carlo's team Chiara, Cecilia, Stefano, Andrea...

09.04.2025 12:34 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

In Seoul they give fluid resuscitation to pine trees, I wonder if it is aggressive or moderate

06.04.2025 07:45 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Proud to receive the prize for the best oral presentation of the International Biliary Pancreatic Meeting 2025 in Seoul, validation of PAN-PROMISE score for its application in RCTs in acute pancreatitis
Thanks to the scientific committee!

05.04.2025 08:49 β€” πŸ‘ 14    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
Post image

… and so the story continues @demadaria.bsky.social presenting the #Waterfinder study in #acutepancreatitis as a follow-up to the #Waterfall trial to find the optimal fluid resuscitation

05.04.2025 06:53 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
a green screen with white text

a green screen with white text

Submit your abstract to UEG Week 2025!

Present your research at one of Europe’s largest and most influential congresses in gastroenterology – where science meets a truly multidisciplinary and diverse audience from around the world.

πŸ“ Submit your abstract by April 25!
https://bit.ly/3WODJci

04.04.2025 07:01 β€” πŸ‘ 2    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
Post image Post image

Special session on the benefits of joining @myueg.bsky.social and attending UEG week, and presentation of the new guidelines on exocrine pancreatic insufficiency during the Seoul 2025 IPBM meeting @maloehr.bsky.social

05.04.2025 03:57 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1

Finally also showing the results from the #MITIGATE study in #IgG4RD #igg4ward
#inebilizumab being approved by @fda.gov now for #IgG4RD !

05.04.2025 03:17 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Post image

Excellent talk by @maloehr.bsky.social on advances in autoimmune pancreatitis during Seoul IPBM 2025!

@myueg.bsky.social

05.04.2025 03:05 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1
Post image

@demadaria.bsky.social presenting πŸ§‘β€πŸ« #PROM for #acutepancreatitis ie the PAN-PROMISE symptom Score during the #IPBM2025 πŸ‡°πŸ‡· as used for the #Waterfall study πŸ“š . Appears to be very useful! πŸ“‰

05.04.2025 02:18 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

@demadaria is following 20 prominent accounts