Enrique de-Madaria

Thrilled to be part of the UEG Council Meeting today! UEG is an incredibly vibrant community bringing together experts from across all fields of gastroenterology. Really excited for the opportunities ahead!
@myueg.bsky.social

In this new episode of the UEG Podcast, Pradeep Mundre​ and Jeroen Dekervel dive into how immunotherapy is changing patient outcomes and the role it plays in cancer management.

🔗 https://bit.ly/44R97K3

Gracias bro!

Simvastatin in the prevention of recurrent pancreatitis: a triple-blinded randomised clinical trial (the SIMBA trial) Background Recurrent acute pancreatitis (RAP) or acute-on-chronic flares in chronic pancreatitis (CP) have limited preventive options beyond addressing the underlying aetiology. Statins, due to their ...

Es un placer ver publicado el estudio SIMBA de mi amigo @demadaria.bsky.social Mucho trabajo detras de este estudio.
gut.bmj.com/content/earl...

Thanks for sharing Daniel!

Simvastatin in the prevention of recurrent pancreatitis: a triple-blinded randomised clinical trial (the SIMBA trial) Background Recurrent acute pancreatitis (RAP) or acute-on-chronic flares in chronic pancreatitis (CP) have limited preventive options beyond addressing the underlying aetiology. Statins, due to their ...

Despite the heralded anti-inflammatory actions of statins, simvastatin had no effect on recurrences of acute or acute on chronic flares of #pancreatitis gut.bmj.com/content/earl...

My strange neighbors Mis extraños vecinos

Don't miss the latest post on my blog #DeMadariaVsPlacebo

My strange neighbours

To get to my office, I have to walk through an area with strange people who do weird things: BioFab

And that has been an opportunity!

demadaria.substack.com/p/my-strange...

He is still there, in Brazil Él aun está allí, en Brasil

Don't miss the latest entry on my blog

He is still there, in Brazil

How a French doctor influenced several generations of Brazilian colleagues

demadaria.substack.com/p/he-is-stil...

9 years in 7 minutes 9 años en 7 minutos

9 years in 7 minutes

How does it feel when, after 9 years of work, a clinical trial like SIMBA is presented for 7 minutes at a conference?
#UEGweek #Berlin

Don't miss the latest post on my blog #DeMadariaVsPlacebo

demadaria.substack.com/p/9-years-in...

ein Mann mit verschränkten Armen

eine Gruppe von Menschen steht in einem Flur

Congratulations to our newly elected council members:

Silvio Danese, Vice President
@iagorlago.bsky.social​, Chair Elect Education Committee

Chloé Melchior, Research Committee Chair
@demadaria.bsky.social​​, Independent Councillor

We are looking forward to working with you! ​

The Difficult Decision of the Daruma’s Eye La difícil decisión del ojo del Daruma

Don't miss the latest post on my clinical research blog #DeMadariaVsPlacebo

The Difficult Decision of the Daruma's Eye

When you have to decide which exciting project to focus on

demadaria.substack.com/p/the-diffic...

Best of @myueg.bsky.social session during the Panamerican Gastroenterology week in Lima, Peru #SPED2025 @maloehr.bsky.social

How to make your collaborative clinical study fail Como conseguir que tu estudio clínico colaborativo fracase

Don't miss the new post on my blog DeMadaria Vs Placebo.

Following the success of How to Get Your Article Rejected and 10 Tricks to Be a Terrible Mentor, here comes How to Fail in Your Collaborative Study.

demadaria.substack.com/p/how-to-mak...

Should GI bleeding/altered mental status be considered organ failure in acute pancreatitis? Pancreatology

Our latest publication: This study evaluates the independent associations of GIB and IMS with morbidity and mortality in AP

authors.elsevier.com/a/1lYrs53tct...

Bring Harvard to your CV! Last days for early bird registration Lleva a Harvard a tu CV

Final days for Early Bird Registration!

Join the Harvard postgraduate course on pancreatic diseases and bring Harvard to your CV

Learn the best and discover brand-new lectures not included in previous editions

open.substack.com/pub/demadari...

Bile from polar bears La bilis de los osos polares

There is a drug called ursodeoxycholic acid that dissolves gallstones. Urso means “bear” in Latin. Why is it called that?

Why does our OSOPOLAR (POLAR BEAR) clinical trial have that name?

Read my latest blog post
👇🏻👇🏻👇🏻
demadaria.substack.com/p/bile-from-...

Nice abdominal X-ray

🥳👉Very happy to share our latest paper published in Endoscopy

🙌Great team effort from 17 🇪🇺centers

PPI 💊 intake lead to ↗️ LAMS occlusion and ↗️ necrosectomy rates addressing WONs but 🩸complication same as No PPI

What is your practice?

tinyurl.com/2ubsu5u4

I particularly love the corn-pancreas

How and when do we become infected with Helicobacter pylori? H. pylori: The Most Common Chronic Infection in Humans — But How Do We Catch It?

How and when do we become infected with Helicobacter pylori?

From my blog for patients "The Pitch of The Stomach"

thepitofthestomach.substack.com/p/how-and-wh...

How to Survive and Succeed in the Design and Execution of a Collaborative Randomized Controlled Trial This article guides the design and execution of successful collaborative randomized controlled trials (RCTs). Aimed at researchers looking to impact clinical practice, it highlights the advantages of....

Just published in @UEGJournal : “How to Survive and Succeed in the Design and Execution of a Collaborative Randomized Controlled Trial”

There you have all the tricks I've learned over the last 15 years about how to conduct a multicenter RCT

All🦾

onlinelibrary.wiley.com/doi/10.1002/...

3/3
This is a very special study for me, as I received the @myueg.bsky.social Research Prize for this project.

Many thanks to all the contributors who have worked so efficiently and passionately!

2/3
With a total of 792 patients from 43 centers across 18 countries from the 5 continents were included in the WATERLAND trial, making it the largest and most globally representative randomized clinical trial conducted in acute pancreatitis to date.

1/3
The abstract with the results of WATERLAND, an RCT comparing lactated Ringer's solution vs. normal saline in fluid therapy for acute pancreatitis, has just been submitted to the UEG Week Berlin October 25 @myueg.bsky.social

3/3

We have worked hard on this new edition, we will deal with new topics on September 26th and 27th, all online and with 3 months to watch the talks, soon we will give you more information.

2/3

The first edition was a success, almost 500 people registered from 50 countries, with talks by 34 international experts in pancreatology with the aim of improving your clinical practice

1/3

Very good news: the second edition of the course "Management of Pancreatic Disorders for the Practicing Clinician" co-directed by Yasmin Hernandez-Barco and myself has just been approved by @harvard.edu

Direct Stimulation of Gastric Smooth Muscle Cells via Gq Proteins With Light Optogenetic stimulation enables direct and selective stimulation of smooth muscle cells and thus provides a new opportunity to restore gastric contractility in cases of gastroparesis. Herein, we demo...

¿Será iluminar el estómago una buena estrategia para tratar la gastroparesia?
Resumimos los resultados de un estudio al respecto y su traslación a la práctica clínica
👇👇👇👇
doi.org/10.1111/nmo....

Participating in Chronicity Forlì 2025 invited by my friend Carlo Fabbri #EmiliaRomagna

Great talks on promotion of research, basic research in pancreatic cancer.

Sharing a nice experience with Carlo's team Chiara, Cecilia, Stefano, Andrea...

In Seoul they give fluid resuscitation to pine trees, I wonder if it is aggressive or moderate