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Keavney Lab

@keavneylab.bsky.social

Lab group led by Prof Bernard Keavney focussing on cardiovascular genomics, big data & congenital heart disease in the @uom-bhfcre.bsky.social‬ πŸ«€πŸ§¬ Posts by group members 🌐 https://www.keavneylab.com πŸ“ Manchester, UK

236 Followers  |  226 Following  |  20 Posts  |  Joined: 25.11.2024
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Posts by Keavney Lab (@keavneylab.bsky.social)

Great talk today from our postdoc Yingjuan at the DCVS monthly seminar πŸ«€

05.06.2025 16:33 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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British Heart Foundation Centre of Research Excellence Studentships Find out more about the British Heart Foundation Centre of Research Excellence Studentships available for cardiovascular research.

We have some exciting opportunities for aspiring researchers! Fully funded BHF studentships in interdisciplinary cardiovascular research. Deadline to apply is 6th June

#PhD #studentships

www.bmh.manchester.ac.uk/study/resear...

13.05.2025 09:34 β€” πŸ‘ 3    πŸ” 5    πŸ’¬ 1    πŸ“Œ 1
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Through out February and March, we organised a range of activities as part of a fundraising competition between the BHF Centres for Research Excellence and recipients of Accelerator Awards, which included 8 Universities. Ultimately, we raised a total of Β£3144! Here's a summary of what we got up to

16.04.2025 08:03 β€” πŸ‘ 5    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0
A large hall full of CRE members with a projector screen at the front reading "British Heart Foundation Manchester Centre of Research Excellence"

A large hall full of CRE members with a projector screen at the front reading "British Heart Foundation Manchester Centre of Research Excellence"

Since this account is new we'll start with some catch-ups about what's been going on over a busy couple of months in the CRE - starting with our official launch on 27th February at the Whitworth Art Gallery 🧡

02.04.2025 14:36 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

Last chance to donate to our go red fundraiser! Our researchers have been working hard all month raising money

www.justgiving.com/page/uombhfcre

31.03.2025 17:03 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Fantastic turnout at our bake sale today! Raised Β£700 and counting. This was our last event in a series raising money for @thebhf.bsky.social and today has taken us over Β£3000!

To find out more about our cause and donate visit www.justgiving.com/page/uombhfcre

28.03.2025 16:11 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1
The five themes of the Manchester BHF CRE: cardiovascular genomics and development; heart failure; inflammatory drivers of cardio- and cerebro-vascular disease; cardiovascular data science; and computational modelling, simulation, and large language models (CMSL)

The five themes of the Manchester BHF CRE: cardiovascular genomics and development; heart failure; inflammatory drivers of cardio- and cerebro-vascular disease; cardiovascular data science; and computational modelling, simulation, and large language models (CMSL)

The Manchester BHF CRE advances cardiovascular research by driving interdisciplinary collaboration across 5 themes

We focus on innovative strategies for prevention, diagnosis, treatment & care - combining cutting-edge technology & clinical expertise

See more at www.bhf-cre.manchester.ac.uk

28.03.2025 16:15 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

Congrats to our PhD students Claudia & @tachycardio.bsky.social who both passed their first year vivas yesterday πŸŽ‰

21.03.2025 18:13 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

@fbmh-uom.bsky.social @fbmhdocacad.bsky.social @thebhf.bsky.social @frontiersin.bsky.social

19.03.2025 17:32 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Frontiers | Congenital heart disease presentations in the 15q11.2 microdeletion syndrome

‼️ New review from PhD student Claudia on 15q11.2 (BP1-BP2) microdeletion

BP1-BP2 del causes a syndrome including developmental delays and anatomical malformations including congenital heart disease. Variable expressivity and low penetrance make genetic counselling a challenge

#MedSky #CardioSky πŸ§ͺ

19.03.2025 17:30 β€” πŸ‘ 8    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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British Heart Foundation’s Centre of Research Excellence launches at The University of Manchester The University of Manchester has launched the British Heart Foundation (BHF) Manchester Centre of Research Excellence following an award of Β£4 million to support world-class cardiovascular disease fro...

The University of Manchester has launched the @thebhf.bsky.social Manchester Centre of Research Excellence following an award of Β£4 million to support world-class cardiovascular disease from the leading charity.
www.manchester.ac.uk/about/news/b...

27.02.2025 15:24 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
A presentation in a room with high vaulted ceilings. The slides read "British Heart Foundation Manchester Centre of Research Excellence" with BHF & University of Manchester logos.

A presentation in a room with high vaulted ceilings. The slides read "British Heart Foundation Manchester Centre of Research Excellence" with BHF & University of Manchester logos.

A fantastic day last week celebrating the launch of the BHF Manchester Centre of Research Excellence. Excited for all the work to come over the next 5 years

@thebhf.bsky.social @fbmh-uom.bsky.social

03.03.2025 14:46 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1
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Manchester BHF CRE Heart Month Fundraising Help Manchester BHF CRE raise money to support British Heart Foundation

26 researchers from the Manchester BHF Centre of Research Excellence - including our own @tachycardio.bsky.social & Yingjuan Liu - are aiming to cover 2000 miles by foot this month to raise money for @thebhf.bsky.social πŸšΆπŸƒ

Donations would be greatly appreciated ❀️
www.justgiving.com/page/uombhfcre

24.02.2025 14:02 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1
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The fundamental role of mitochondria–endoplasmic reticulum contacts in ageing and declining healthspan | Open Biology This open question research article highlights mitochondria-associated endoplasmic reticulum (ER) membranes (MAMs), which have emerged as crucial cellular structures that challenge our traditional und...

New review out today in Open Biology, a Royal Society publication on mitochondria-ER contacts and their potential use as therapeutic targets. doi.org/10.1098/rsob... @keavneylab.bsky.social @thebhf.bsky.social @official-uom.bsky.social @gensocuk.bsky.social

12.02.2025 09:24 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 1    πŸ“Œ 1
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Most cardiac arrests happen at home, and knowing CPR could save the life of someone you love. All you need is your phone and a cushion to learn CPR in just 15 minutes, for free with RevivR. Be ready for when it matters most. ❀️ Find out more about RevivR here: bit.ly/3E7D0fg:

07.02.2025 09:10 β€” πŸ‘ 11    πŸ” 12    πŸ’¬ 0    πŸ“Œ 5
Fahmida standing next to a presentation titled "Evaluation of the PURE Diet Score on Cardiovascular Disease and Mortality: Proposed Analysis in the UK Biobank"

Fahmida standing next to a presentation titled "Evaluation of the PURE Diet Score on Cardiovascular Disease and Mortality: Proposed Analysis in the UK Biobank"

Great day at the @uomresearchit.bsky.social UK Biobank showcase today including a brilliant talk from our PhD student @tachycardio.bsky.social!

30.01.2025 15:38 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Looking forward to day 2 of @fogenomics.bsky.social

I'm finding Bluesky a great place to discuss #genomics Here is a starter pack for anyone looking for related accounts to follow. Let me know if you want adding or if have any suggestions! #FOG2025

go.bsky.app/FpcXQK7

30.01.2025 09:47 β€” πŸ‘ 11    πŸ” 4    πŸ’¬ 4    πŸ“Œ 0

Thank you!

30.01.2025 15:03 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Packed house for Prof Martin Rutter, Deputy Chief Scientist @ukbiobank.bsky.social - the first talk of the UoM UK Biobank user group showcase. If you're a UoM researcher using the database, get involved! bit.ly/cadirUKB

30.01.2025 13:23 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1

Hi could you add us?

30.01.2025 13:23 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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An in silico analysis of heart rate impact on wall shear stress hemodynamic parameters in aortic coarctation - Scientific Reports Scientific Reports - An in silico analysis of heart rate impact on wall shear stress hemodynamic parameters in aortic coarctation

New paper from our collaborators in the school of Engineering & University of Cape Town #academicsky πŸ§ͺ
www.nature.com/articles/s41...

22.01.2025 15:34 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Merry Christmas from the Keavney lab πŸŽ„

19.12.2024 17:52 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

πŸ“¦ Here’s a starter pack for @official-uom.bsky.social University of Manchester staff and departments.
πŸ’¬ Reply if you wish to be added
go.bsky.app/pDWEN6

10.12.2024 11:10 β€” πŸ‘ 22    πŸ” 10    πŸ’¬ 32    πŸ“Œ 4

Could you add us please?

11.12.2024 13:43 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

1️⃣ A computational project studying the co-morbidities of congenital heart disease in large datasets using AI & machine learning www.findaphd.com/phds/project...

2️⃣ A wet-lab project using cardiac organoids to screen drugs in heart failure www.findaphd.com/phds/project...

#AcademicSky
πŸ§¬πŸ’»πŸ§ͺπŸ«€

03.12.2024 14:02 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

πŸŽ“ Funded PhD opportunites

We have two #UoM200 bicenntenial PhD projects available in the group. Open to students worldwide & based at Uni of Manchester, UK. Deadline 10th Jan

More info on the projects below ⬇️

#AcademicSky πŸ§¬πŸ’»πŸ§ͺπŸ«€

03.12.2024 14:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

πŸŽ“ Funded PhD opportunity

Computational project studying the co-morbidities of congenital heart disease in large datasets using AI & machine learning

Open to students worldwide - based at Uni of Manchester, UK

www.findaphd.com/phds/project...

#AcademicSky #UoM200 πŸ§¬πŸ’»

28.11.2024 17:08 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

πŸŽ“ Funded PhD opportunity

Computational project studying the co-morbidities of congenital heart disease in large datasets using AI & machine learning

Open to students worldwide - based at Uni of Manchester, UK

www.findaphd.com/phds/project...

#AcademicSky #UoM200 πŸ§¬πŸ’»

28.11.2024 17:08 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
A graph showing that CHD cases have a higher risk of both hospitalisation & death pre-vaccination (for COVID-19). Post-vaccination the risks of both are significantly reduced, but still higher in CHD cases than controls

A graph showing that CHD cases have a higher risk of both hospitalisation & death pre-vaccination (for COVID-19). Post-vaccination the risks of both are significantly reduced, but still higher in CHD cases than controls

We showed that vaccination significantly decreased COVID-19 related hospitalisation & mortality in congenital heart disease patients, but even post-vaccine they have a higher risk of severe outcomes. Made possible by @thebhf.bsky.social Data Science Centre

heart.bmj.com/content/110/... πŸ§¬πŸ’»πŸ«€

28.11.2024 15:23 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Keavney Lab | British Heart Foundation | AV Hill Building, Manchester, UK Keavney Lab, a research group led by Professor Bernard Keavney and supported by the British Heart Foundation.

Hi please could you add us - this is our PI's profile research.manchester.ac.uk/en/persons/b...

27.11.2024 17:22 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0