Darragh O'Brien

Great start to the global AAIC Neuroscience Next 2026 Conference at the UK Hub in-person event in Manchester.

#Lewybodydementia #NeuroscienceNext #AAIC #dementiaresearch #Manchester

How people with brain disorders reveal important insights into our selves
www.waterstones.com/events/our-b...

🧠What an amazing day we had yesterday at the @alzheimersocirl.bsky.social & DRNI event "Brain Health and Dementia: Understanding and Connection"!

👏Thanks so much to all the wonderful attendees for their interest, engagement, and participation, and to all the fantastic speakers!

😱 Only ONE day left to submit your abstract to DRNI ECR Day!

➡️ To submit an abstract or to register to attend, go to: dementianetwork.ie/news-item/dr...

AAIC Neuroscience Next Excellence in Neuroscience Mentoring Award Selina Wray, Ph.D.

Congratulations to the University College London’s Selina Wray, Ph.D., recipient of the #AAICNeuro Excellence in Neuroscience Mentoring Award.

Research Assistant: Neuronal Cell Biologist in Parkinson’s University of Oxford DPAG seeks Research Assistant to work on iPSC models and Parkinson’s cell biology in the Laboratory of Molecular Neurodegeneration.

Research Assistant role at University of Oxford DPAG. Work with iPSC derived neurons and glia to study Parkinson’s molecular and cellular biology. Closing date: 16th March

www.dementiaresearcher.nihr.ac.uk/job/research...

Are you a health or social care professional working with PSP or CBD? Our #free guides offer practical insights to help you provide the best care. Download and share with your colleagues to make a difference!
👉 ow.ly/WjWx50Y4W2a #PSP #CBD #Downloads #Guides

Happy New Year! ✨

Wishing you all a brilliant 2026 🥳🎉

#2026

PhD: Astrocyte-Microglia Crosstalk in Alzheimer’s Fully funded PhD at UK Dementia Research Institute UCL, London, studying astrocyte microglia crosstalk and synaptic loss in Alzheimer disease.

Fully funded PhD at @ukdri.ac.uk UCL, London, studying astrocyte microglia crosstalk and synaptic loss in Alzheimer disease.

www.dementiaresearcher.nihr.ac.uk/job/phd-astr...

The Radcliffe Camera and surrounding Bodleian buildings in Oxford at sunset, with a pink and orange winter sky glowing above the historic stone architecture.

Yesterday's sunset 🌅

📷 Instagram | 12AtOxford

Had a great time representing the Human Brain Proteome Project during the "Friends of HUPO" social at #HUPO2025 last night. If you want to get involved, or simply hear more about the initiative, please get in touch 🧠

Postdoc Researcher: Modelling Alzheimer’s’ with iPSCs & AI Phenotyping Two Postdoctoral Researchers at University of Oxford to study Alzheimer’s disease using AI and iPSC models in the Translational Neuroscience Group.

Two Postdoctoral Researcher Positions at University of Oxford to study Alzheimer’s disease using AI and iPSC models in the Translational Neuroscience Group. Closing date: 6th November

www.dementiaresearcher.nihr.ac.uk/job/postdoc-...

#AAICNeuro

www.dementiaresearcher.nihr.ac.uk/aaic-neurosc...

Aerial view of the University of Oxford, showcasing its historic buildings and spires under a clear sky at sunset. Text overlay states "Oxford named best university in the world for a record tenth consecutive year".

NEW: We’re honoured to be ranked number one in the Times Higher Education World University Rankings for the tenth consecutive year. 👏

Many thanks for the spotlight! "Trasna na dTonnta" (Across the Waves) is a great initiative from @drni.bsky.social for the Irish dementia research diaspora – a global community linking Irish dementia researchers on the island of Ireland to those undertaking research abroad #brainwaves 🧠🌊

Research Associate: Extracellular Vesicle Biomarkers University of Oxford seeks Research Associate to study extracellular vesicles and biomarkers in Parkinson’s disease using blood samples and iPSC based models.

University of Oxford seeks Research Associate to study extracellular vesicles and biomarkers in Parkinson’s disease using blood samples and iPSC based models. Closing date: 3rd October

www.dementiaresearcher.nihr.ac.uk/job/research...

Excited contribute to this year’s lunch hour lecture program! It’s a free event and accessible to a non-specialist audience so please come and join me :)

Trans-synaptic tau propagation in progressive supranuclear palsy Nature Reviews Neurology, Published online: 05 August 2025; doi:10.1038/s41582-025-01129-zNew evidence supports trans-synaptic propagation of tau pathology in the neurodegenerative disease progressive supranuclear palsy.

ICYMI: New online! Trans-synaptic tau propagation in progressive supranuclear palsy

YouTube video by Dementia Researcher Blood Biomarkers & Testing for Alzheimer’s Disease

Blood Biomarkers: Testing for Alzheimer’s Disease

Professor Jonathan Schott @jmschott.bsky.social (UCL) explains how blood tests are reshaping Alzheimer’s diagnosis. Clear, current and clinically relevant.

Recorded at the Wessex Dementia Research Conference

youtu.be/3fLl1Mzwbsk

Tracking tau and cellular responses in human iPSC-microglia from uptake to seedable secretion in extracellular vesicles The templated spread of tau aggregates in tauopathies has been attributed to neuron-to- neuron spread, but microglia have also been implicated through mouse studies. Here we examine in detail the upta...

A great story to be part of! Kudos to Mária, Anna, Anne, Sally and all of the team🧠

Encaenia 2025 @ox.ac.uk with my 🧠 buddy @stephfowler.bsky.social. It was great to see fellow Enniscorthy native Colm Tóibín receive the honorary degree of Doctor of Letters for his contribution to literature and journalism 💜💛

Fantastic start to the day here at the 3rd "Human Proteome and Health" Symposium at Rhodes House where Dr Katerina Gospodinova from the ARUK-ODDI and @cmd.ox.ac.uk discussed proteomic profiling of the #matrisome for use a novel therapeutic modality in #Alzheimers Disease 🧠 @arukthamesv.bsky.social

Driving Therapeutic Innovation in Neurodegenerative Disease with Hydrogen Deuterium eXchange Mass Spectrometry Human neurodegenerative conditions such as Parkinson’s and Alzheimer’s Disease are characterized by the formation and deposition of toxic protein species which exacerbate neuronal dysfunction, impacti...

Our review is out now in Molecular & Cellular Proteomics! We discuss the latest advances in #HDX mass spectrometry to aid neurotherapeutic design & development in #Alzheimers, #Parkinsons and #ALS, providing molecular insights into protein aggregation pathways and therapeutic antibodies 🧠

External link live! Please share widely :-)

WE ARE RECRUITING! 🥳

Are you an epidemiologist with strong quantitative skills and an interest in contributing to exciting research into the genetic architecture of vascular dementia? Come join our friendly and productive team at UCL!

shorturl.at/aZ5Ua

Extracellular vesicles in TDP-43 proteinopathies: pathogenesis and biomarker potential - Molecular Neurodegeneration Extracellular vesicles (EVs) are membrane-enclosed nanoparticles released by most cell types, and from multiple sub-cellular compartments. They carry a range of cargo biomolecules, including protein a...

Very pleased to share our review in @molneurodegen.bsky.social, assessing evidence for #ExtracellularVesicle associated #TDP43. We highlight knowledge gaps relating to its biomarker usage and possible involvement in seeding of templated aggregation in #ALS, #FTD and #LATE.
doi.org/10.1186/s130...

Check out our June issue!

www.nature.com/neuro/volume...

Dementia Researcher: Clinical opportunity for Blood-based Biomarkers In this episode of the Dementia Researcher podcast, host Dr Amanda Heslegrave leads an insightful discussion on one of the most promising developments in dementia diagnostics: blood-based biomarker...

Could blood tests reduce diagnostic delays for dementia? Experts weigh in on our podcast – don’t miss this timely discussion with @ajh1269.bsky.social‬ @ukdri.ac.uk‬ Dr Mark Roskey from Quanterix and Dr Jay Amin, University of Southampton

On the importance of reading (just not too much) The real fun of being a neuroscientist, and maybe the key to asking and answering new questions, is to think big and take intellectual risks.

Keeping up with the literature is essential. But so is devoting time to developing your own scientific ideas, writes Sheena Josselyn.

#neuroskyence

www.thetransmitter.org/craft-and-ca...

UCL – University College London UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

🚨MRC Research Fellow Vacancy:

Studying microglial ageing utilising iPSC-based cell biology, screening, biochemistry, genomics, imaging & bioinformatics

@dervissalih1.bsky.social, UK DRI at UCL

🗓️ Closing 26 June

👉 www.ucl.ac.uk/work-at-ucl/...

Research Fellow: Immune system and Cognitive function Join the UKDRI at UCL in the Salih Lab to explore how glial-specific longevity genes affect ageing & Alzheimer’s using iPSC models, genomics & molecular biology

Join the UKDRI at UCL in the Salih Lab to explore how glial-specific longevity genes affect ageing and Alzheimer’s, using iPSC models, genomics, and molecular biology @ukdri.ac.uk @dervissalih1.bsky.social Closing date: 26th June

www.dementiaresearcher.nihr.ac.uk/job/research...